Top-Tier Supplement Brands for Optimal Health Boosts

In the ever-expanding world of health and wellness, choosing the right supplement brand can make a notable difference in achieving your health goals. With numerous companies vying for attention, it’s essential to focus on brands that prioritize quality ingredients, transparency, and scientific backing. Factors such as third-party testing, sourcing practices, and customer reviews play a critical role in distinguishing the best from the rest. To help you navigate this landscape, here's a curated list of top supplement brands that have consistently stood out for their commitment to excellence. Explore the selections and find out which brand aligns with your health needs below.

Illustration of supplements

Best brands of supplements in 2025

Optimum Nutrition

Optimum Nutrition, a flagship brand of Glanbia, stands as the world's #1 sports nutrition brand, renowned for its uncompromising quality and global presence. It has achieved remarkable growth, with its sales doubling in the US from 2017 to 2022, and it is the #1 sports nutrition protein powder in both retail and e-commerce channels. The brand's consumer base is affluent and highly engaged, with consumers spending 28% more on sports nutrition products and working out 80% more often than average users. Optimum Nutrition's global revenue has reached $1 billion, driven by its strong brand reputation and innovative product offerings. The brand is consistently ranked high in consumer trust, with strong NPS scores in various markets. For more information about their innovative product offerings, visit the Optimum Nutrition website.

Garden of Life

Garden of Life is a leading brand in the supplements industry, known for its high-quality, organic products. Since joining Nestle Health Science in 2017, the company has maintained a 10% market share in the US and has experienced double-digit growth over the past decade. Garden of Life is the number one brand in vitamins, probiotics, plant-based protein, and sports nutrition, with its products being category leaders at retailers like Whole Foods, Sprouts, and Amazon.com. The company's revenue has grown at a 30% CAGR over the past five years, reaching nearly $250 million. Garden of Life's commitment to using Certified USDA Organic plants and non-GMO verified ingredients has earned it a trusted reputation among consumers. For more details on their products, visit Garden of Life's official website.

Nature's Bounty

Nature's Bounty is a leading brand in the supplement industry, renowned for its commitment to quality, consistency, and scientific research. With a market share of more than 5.0% in the US vitamin and supplement manufacturing sector, Nature's Bounty stands out for its diverse product lines and stringent quality assurance standards, including GMP compliance and audits by the United States Pharmacopeia. The company's products, which include vitamins, minerals, and herbal supplements, are trusted by health-conscious consumers for decades. Nature's Bounty's dedication to excellence has resulted in supplements of unrivaled quality, making it a significant player in the global market projected to grow at a CAGR of 7.6% from 2024 to 2034. For more information, explore Nature's Bounty's offerings on their official website.

NOW Foods

NOW Foods is a leading producer in the supplement industry, renowned for its high-quality products and commitment to health and wellness. The company is a key player in both the natural health supplement market, which is projected to reach $121.76 billion by 2034 with a 7.6% CAGR, and the vitamin supplement market, expected to grow to $115.5 billion by 2034 at a 7.5% CAGR. NOW Foods offers a diverse range of supplements, including heart health and vitamin supplements, catering to the increasing demand for preventive healthcare. The company's products are widely distributed, with pharmacies holding a significant market share of 23.78% in the natural health supplement market. NOW Foods' presence in the market is further strengthened by its inclusion among prominent vendors in both the natural health and vitamin supplement sectors.

Jarrow Formulas

Jarrow Formulas is a renowned brand in the dietary supplement industry, celebrated for its high-quality and science-backed products. In 2019, it was chosen as the #1 Probiotics Brand for customer satisfaction by ConsumerLab.com, with the highest percentage of "Very Satisfied" responses from 10,931 survey participants. The company has been a pioneer in probiotics for over 30 years, introducing innovative multi-strain formulas and combining shelf stability with enteric coating. Jarrow Formulas' products are carefully crafted using superior science and quality ingredients, earning trust from customers for over 50 years. Their commitment to quality is further validated by numerous approvals from ConsumerLab.com. For more information about their products, visit their official website.

Pure Encapsulations

Pure Encapsulations is a highly reputable brand in the dietary supplement industry, known for its hypoallergenic and high-quality products that are free from unnecessary additives and common allergens. With over 30 years of research and innovation, the brand offers a comprehensive line of more than 400 supplements, many of which are certified gluten-free and non-GMO. Their products are rigorously tested by independent labs to ensure safety, purity, and potency, exceeding standards set by USP and CGMPs. Customer reviews highlight the efficacy and quality of products like the magnesium glycinate supplement, which has a 4.7 out of 5-star rating on Amazon based on over 29,000 reviews. Pure Encapsulations' commitment to quality and customer satisfaction has earned it a positive reputation among healthcare professionals and consumers alike. For more information, visit their official website.

Thorne Research

Thorne Research, a leading brand in the health and wellness industry, has demonstrated remarkable growth and innovation in the supplement market. In 2022, Thorne HealthTech reported a 27.7% year-over-year increase in net sales to $63.0 million, with direct-to-consumer sales growing by 46.1%. The company's full-year growth rates for 2021 included a 34% increase in both net sales and adjusted EBITDA, driven by an expanding consumer base and health professionals trusting their integrated platform. Thorne's commitment to science-backed solutions and personalized health approaches has earned it recognition, such as being named one of Fast Company's Top 10 Most Innovative Companies in Wellness for 2023. Their products, including supplements and health tests, are designed to enhance overall wellness and performance. For more information, visit their official website.

Life Extension

Life Extension is a renowned brand in the supplement industry, known for its clinically-studied and premium vitamins and supplements. With over 40 years of experience in promoting healthy living, Life Extension offers a wide range of products, including the popular Neuro-Mag® Magnesium L-Threonate, which supports memory, quick thinking, and cognitive health. The brand's commitment to science-backed products has made it a trusted name among consumers. Life Extension's products are available through various distribution channels, including online platforms, contributing to the growth of the global vitamin supplements market, which is expected to reach USD 87.25 billion by 2031 with a CAGR of 7.5% from 2024 to 2031. The brand's focus on preventive healthcare aligns with the increasing health consciousness among consumers, particularly in regions like North America, which dominates the market with a 38.6% share in 2024. For more information, visit the Life Extension website.

MegaFood

MegaFood, founded in 1973, is a renowned brand in the supplement industry, celebrated for its 50th anniversary in 2023. As a Certified B Corporation, MegaFood prioritizes environmental performance, transparency, and legal accountability, adhering to high standards such as testing for 150+ pesticides and being Non-GMO Project Verified and Certified Glyphosate Residue Free. The brand is committed to regenerative agriculture and has been a member of 1% for the Planet since its certification in 2018. MegaFood's products are clinically tested and contain real food, ensuring they are highly efficacious and meet the recommended daily value of 20% or more per serving. Their dedication to sustainability and quality has made them a trusted name in the health and wellness sector. For more information, visit their official website.

Solgar

Solgar, a brand under Nestle Health Science, is renowned for its commitment to quality, health, and well-being, with over 70 years of experience in creating the finest nutritional supplements. Known as "The Gold Standard," Solgar focuses on science-backed formulas, responsibly sourced ingredients, and avoids artificial ingredients or fillers. Their products are manufactured in small batches with high-quality standards, including USP water filtration and HEPA air filtration, and are packaged in recyclable amber glass bottles. Solgar's supplements, such as their Ester-C Vitamin C, are highly regarded for their purity and effectiveness, making them a preferred choice among health-conscious consumers. The brand's dedication to innovation and community commitment further solidifies its position as a leading producer in the supplement market. For more information about their products, visit Solgar's official page.