Top Simethicone Brands for Effective Gas Relief

When it comes to dealing with uncomfortable bloating and gas, simethicone is a popular over-the-counter remedy known for its effectiveness. Many brands produce simethicone-based products, offering various formulas and dosages to cater to individual needs. From reputed brands like Gas-X and Phazyme to family favorites such as Equate and Little Remedies, the options are vast. For a comprehensive guide to the best simethicone brands suited for your needs, explore the detailed list below.

Illustration of simethicone

Best brands of simethicone in 2025

Gas-X

Gas-X is a leading brand in producing simethicone, an anti-flatulence agent that effectively relieves pressure, bloating, and gas symptoms by decreasing the surface tension of gas bubbles in the gastrointestinal tract. Since its FDA approval in 1952, Gas-X has been a trusted name, with products such as Maximum Strength Softgels and Extra Strength Chewable Tablets containing up to 250mg of simethicone per dose. Gas-X products are designed for various age groups, including infants, children, and adults, with a maximum daily dosage of 500mg for nonprescription use. The brand's formulations, including oral suspensions and softgels, ensure easy administration and minimal systemic absorption, making it safe for use during pregnancy and breastfeeding. Gas-X simethicone is also used in gastrointestinal diagnostic procedures to improve visualization.

Phazyme

Phazyme is a renowned brand known for its effective and strong simethicone products, providing reliable gas relief for over 30 years since its inception in the 1970s. It offers the highest dosage of simethicone available without a prescription, with options up to 500mg per pill, making it a top choice for severe gas pain and bloating. Phazyme has a favorable rating, with 100% of reviewers on Drugs.com reporting a positive effect. The brand is now owned by Fleet Laboratories, a company with over 140 years in the personal healthcare industry. Phazyme products are available in various forms, including chewable tablets and softgels, ensuring fast and effective relief. For more information, visit the Phazyme official page.

Mylanta

Mylanta is a leading brand in producing effective antacid and anti-gas medications, particularly notable for its inclusion of simethicone, which helps break down gas bubbles in the stomach and intestines, providing quick relief from bloating and discomfort. Mylanta's formulations, such as Mylanta Maximum Strength and Mylanta Coat & Cool, contain 80 mg of simethicone per 10 mL dose, along with antacids like calcium carbonate and magnesium hydroxide to neutralize stomach acid. Introduced back in the market in 2016 after a brief recall, Mylanta has established itself as a top choice, with its Maximum Strength formula offering 45% more acid-neutralizing capacity than TUMS. The brand is recommended by doctors and trusted by consumers for its fast-acting and gentle relief from heartburn, acid indigestion, and gas symptoms. Mylanta's products are available in various flavors and forms, including liquids and tablets, to cater to different needs. For detailed information about their Mylanta Maximum Strength Liquid Antacid, visit their official website.

Maalox

Maalox, a renowned brand owned by Novartis, is highly regarded for its effective antacid and anti-gas formulations, particularly those containing simethicone. The Maalox Advanced Maximum Strength Cherry liquid, for example, includes 400 mg of aluminum hydroxide, 400 mg of magnesium hydroxide, and 40 mg of simethicone per 5 mL, making it a potent remedy for heartburn, acid indigestion, and gas-related discomfort. Introduced commercially in 1949, Maalox has a long history of providing relief from stomach acid and gas issues. The simethicone in Maalox helps break up gas bubbles in the gut, providing quick and effective relief. The product is available in various flavors and forms, including liquid suspensions and chewable tablets.

Tums Chewy Bites + Gas Relief

TUMS Chewy Bites with Gas Relief is a top-tier product for those seeking simultaneous heartburn and gas relief, featuring 750mg of calcium carbonate to neutralize stomach acid and 80mg of simethicone to break up gas bubbles. This formulation provides fast and effective relief from heartburn, acid indigestion, sour stomach, and upset stomach, with a maximum daily dose of 6 tablets. Recommended by doctors, pharmacists, and OBGYNs, TUMS has been a trusted brand for 90 years. These chewable tablets come in lemon and strawberry flavors and are gluten-free. They are designed for adults and children 12 years and older, with a resealable bottle for convenience. For more information, visit the TUMS Chewy Bites product page.

Alka-Seltzer Anti-Gas

Alka-Seltzer Anti-Gas, a product from the renowned Alka-Seltzer brand owned by Bayer since 1978, is a leading provider of simethicone, a medication used to relieve painful pressure caused by excess gas in the stomach and intestines. This medicine is suitable for babies, children, and adults, making it a versatile solution for gas discomfort. Alka-Seltzer Anti-Gas contains simethicone, which helps to break up gas bubbles in the stomach and intestines, providing quick and effective relief. It is important to note that users should not exceed the recommended dosage and consult a doctor if they have any serious illnesses or allergies. The product is widely available and has been trusted for decades for its efficacy in managing gas-related symptoms.

Equate

Equate, the Walmart brand, is renowned for producing high-quality simethicone products, such as the Equate Antacid Maximum Strength, which contains 400mg of aluminum hydroxide, 400mg of magnesium hydroxide, and 40mg of simethicone per 5mL, providing fast and effective relief from heartburn, acid indigestion, and gas. This formulation is comparable to leading brands like Mylanta and is available without a prescription. The product is designed for adults and children over 12 years, with a recommended dosage of 2-4 teaspoonsful (10-20 mL) between meals or at bedtime. Equate's simethicone products are widely trusted for their efficacy and safety, with minimal reported side effects. By following the manufacturer's instructions, users can effectively manage gas and digestive discomfort.

Kirkland Signature

Kirkland Signature, the private label brand of Costco, is renowned for its high-quality products, although it is not specifically known for producing simethicone. However, Kirkland Signature has seen significant growth in its market penetration, reaching the high 20s percent, and continues to enhance its value proposition with new items like Organic Golden Maple Syrup and Aerosol Whipped Cream. In the 52-week fiscal year, Costco reported net sales of $249.6 billion, a 5% increase from the previous year. The brand's success is attributed to its ability to offer significant member value compared to national brands. Despite this, there is no specific data indicating Kirkland Signature as a producer of simethicone. For more information about their product offerings, visit the Costco website.

Beano + Dairy Defense

Beano + Dairy Defense is a leading brand in the production of dietary supplements designed to prevent gas, bloating, and discomfort caused by various foods, including vegetables, beans, whole grains, and dairy products. This product contains two natural food enzymes that break down complex carbohydrates and lactose, making these foods easier to digest. It is gluten-free, naturally and artificially flavored, and each tablet contains less than five milligrams of sodium. For optimal results, users are advised to take one chewable tablet before each meal that includes problem foods. Beano + Dairy Defense is manufactured in the USA and is available in various retail outlets, including Instacart.

Gaviscon Extra Strength

Gaviscon Extra Strength is renowned for its antacid properties, effectively relieving heartburn, sour stomach, and acid indigestion with its active ingredients of aluminum hydroxide and magnesium carbonate. Each tablet contains 160mg of aluminum hydroxide and 105mg of magnesium carbonate, available in Original and Cherry flavors. For optimal relief, Gaviscon Extra Strength tablets should be chewed after meals and at bedtime, with a maximum of 16 tablets permissible within 24 hours. This product is ideal for those seeking fast-acting, long-lasting relief from heartburn and acid reflux symptoms. However, it's essential to consult a doctor if you're on a sodium-restricted diet or taking prescription drugs. For further information about their tablets, visit the Gaviscon product page.