Top AHCC Brands: Unlocking Optimal Health Benefits

AHCC, or Active Hexose Correlated Compound, has gained significant attention in recent years for its potential health benefits, particularly in immune support. As the popularity of AHCC continues to rise, so does the number of brands offering this sought-after supplement. With various options available, selecting the right brand can become a daunting task, but focusing on quality and credibility can help narrow down the choices. To assist you in making an informed decision, we have compiled a list of the best AHCC brands, ensuring you receive the finest possible product for your needs. Read below to discover which brands stand out and why they're highly recommended in the AHCC market.

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Best brands of ahcc in 2025

Quality of Life

Quality of Life is a leading brand in AHCC production, with their Kinoko Platinum product containing 750mg of AHCC per capsule, backed by over 30 human clinical trials demonstrating its effectiveness in supporting immune health by enhancing natural killer cell activity. Studies show around a 60% success rate in clearing persistent HPV infections in women using AHCC daily for at least six months, with research also indicating improved 5-year survival rates for certain cancer patients using AHCC (79.6% vs 53.2% in one study). The unique formulation of Quality of Life's AHCC is rich in alpha-glucans and is used by over 1,000 clinics worldwide. Their AHCC products are manufactured in GMP certified facilities.

Source Naturals

Source Naturals, established in 1982, is a reputable brand that produces AHCC, a proprietary compound derived from shiitake mushroom mycelia, with studies suggesting it may significantly increase Natural Killer (NK) cell activity and support the immune system. Their AHCC product contains a proprietary blend that includes mushroom mycelia extract, carnauba wax, cyclodextrin, and microcrystalline cellulose, and is available in 500mg capsules, often with a suggested use of two capsules twice or three times daily on an empty stomach. Research indicates that AHCC may also enhance macrophage activity and cytokine production, while acting as an antioxidant and supporting healthy liver function. Source Naturals AHCC has been researched extensively for its immune enhancement properties.

ImmPower

ImmPower, a leading brand since 1999, is renowned for its high-quality AHCC supplement, a unique mushroom extract with a low molecular weight of around 5,000 daltons, containing approximately 20% alpha-1,4-glucans. It has been shown in studies to support the immune system by enhancing Natural Killer cell function, cytokine production, and T-cell activity. Produced by American BioSciences, ImmPower is available in vegetarian capsules, offering a common dosage of 500mg per capsule and backed by over 80 clinical trials. You can find more information at American BioSciences.

Now Foods

NOW Foods, established as a reputable brand, offers AHCC (Active Hexose Correlated Compound), a mushroom mycelia extract-based supplement, with both regular (500mg per capsule) and extra strength (750mg per capsule) options for immune support. This supplement contains a proprietary blend of mushroom mycelia extract, candelilla wax, cyclodextrin, and cellulose, and is also recognized for its antioxidant properties and support of healthy liver function since its release in 2012. It is vegan/vegetarian, soy-free, egg-free, dairy-free, nut-free, kosher, made without gluten, and GMP quality assured.

Swanson

Swanson brand, a producer of high-quality supplements for nearly 50 years, offers a maximum strength AHCC supplement, with each capsule containing 500mg of a proprietary extract derived from Basidiomycetes mushrooms, traditionally used in Eastern medicine, which is formulated to support immune health, strengthen the body's defense system, and also provides liver support. It is manufactured in GMP certified facilities with third-party purity testing. For more information about this AHCC supplement, please visit their website.

Solaray

Solaray is a reputable brand, offering AHCC, a mushroom mycelia extract, combined with 225mg of NAC and 50mg of Beta Glucan per capsule, formulated to support healthy immune function; with a standardized extract of cultured Lentinula edodes mycelia, Solaray's AHCC product is lab verified and comes in a 30-VegCap bottle, and is intended to be taken twice daily between meals.

Mushroom Wisdom

Mushroom Wisdom is a leading producer of AHCC, a unique mushroom extract rich in alpha-glucans, not beta-glucans, supported by over 40 peer-reviewed articles showing its ability to enhance the immune system, particularly Natural Killer cell function. This extract has been used since 1989, with some studies showing a 58% success rate in clearing persistent HPV infections. Their products contain a minimum of 10% short chain alpha glucans, ensuring potent effectiveness.

Jarrow Formulas

Jarrow Formulas is a reputable brand producing AHCC, a unique mushroom mycelia extract, with their product containing partly acylated alpha-1,4 glucans. While not providing exact percentages, studies have shown AHCC to be 58% effective in clearing persistent HPV infections, and it has been used since its launch in 1989. Jarrow Formulas' AHCC is known for its quality and is available in various forms. The proprietary manufacturing process of the AHCC by Amino Up Co., Ltd., ensures a consistent and standardized quality of the product. You can find Jarrow Formulas AHCC products at various retailers; for example, one such product can be found at Vitamin Shoppe.

Life Extension

Life Extension, established in 1980, is a well-known brand that offers a range of science-backed supplements, including AHCC, which is derived from a blend of medicinal mushroom mycelia and is used to support immune function by activating macrophages and promoting NK cell proliferation, with studies suggesting that AHCC has a 58% success rate in clearing persistent HPV infections. Life Extension also provides other health-related products based on scientific research.

Relentless Improvement

Relentless Improvement, established in 2005, is a trusted producer of AHCC, offering a high-quality mushroom extract with a 25% alpha-glucan content, sourced from a specific supplier in China and rigorously tested in a USA-based lab. Their AHCC product is known for its use in immune support, and is comparable to other AHCC brands, with many users reporting positive results in immune health and resolution of health issues. It is also used in over 700 hospitals in Japan. The company specifies vegecaps for all encapsulated products and sells directly to consumers to maintain freshness and quality.