Top Magnesium Orotate Brands for Optimal Health

Magnesium orotate is a popular supplement for those looking to support heart health, improve endurance, or simply boost their overall magnesium levels. Known for its high bioavailability, magnesium orotate is absorbed more efficiently by the body compared to other forms of magnesium supplements. When choosing a brand, it's important to consider factors such as purity, potency, and value for money. To help you make an informed choice, we've carefully curated a list of the best brands offering magnesium orotate supplements below.

Illustration of magnesium orotate

Best brands of magnesium orotate in 2025

Klaire Labs

Klaire Labs is renowned for its high-quality magnesium supplements, including the Magnesium Glycinate Complex, which offers a highly bioavailable form of magnesium bound with the amino acid glycine. This formulation is designed for optimal absorption and is well-tolerated, even by sensitive individuals. Magnesium from Klaire Labs plays a vital role in energy production, enzymatic processes, vascular tone regulation, and the regulation of calcium and potassium metabolism. The product upholds rigorous standards of purity and potency, making it a trusted choice among health professionals. Each capsule provides a significant amount of magnesium, supporting overall health and well-being.

Advanced Research

Advanced Research, founded on the principles of Dr. Hans Nieper, is a renowned brand for producing high-quality magnesium orotate supplements. Dr. Nieper's research emphasized the use of orotates as mineral transporters to enhance bioavailability, and his formulas support various bodily systems, including cardiovascular, lymphatic, and muscular systems. Magnesium orotate from Advanced Research contains 500 mg per tablet, with each serving providing 63 mg of elemental magnesium, which is 15% of the Daily Value (DV) for individuals under 50 years old. This supplement is used to treat magnesium deficiency and support over 300 biochemical reactions in the body. Advanced Research ensures meticulous manufacturing and scientific formulation to meet Dr. Nieper's standards of excellence.

Cardiovascular Research Ltd.

Cardiovascular Research Ltd., through brands like AOR Inc., stands out as a top producer of magnesium orotate, offering high-quality supplements like Cardio Mag 2.0. This product is designed to support heart health by enhancing cardiac muscle function, boosting cellular energy production, and minimizing cardiovascular risks. Clinical evidence suggests that magnesium orotate can reduce symptoms of chronic heart failure by up to 30%, improve physical performance, and decrease the frequency of angina episodes. This form of magnesium is well-tolerated, causing fewer gastrointestinal side effects compared to other magnesium salts, and it offers superior bioavailability, ensuring higher intracellular magnesium levels. The recommended daily dose ranges from 200 to 400 mg, and it is often recommended to start with the lower end of this range and adjust as needed under professional guidance. Magnesium orotate's unique combination with orotic acid supports ATP production, protein biosynthesis, and the production of pyrimidine nucleotides, making it a superior choice for cardiovascular support.

Pure Encapsulations

Pure Encapsulations is renowned for its high-quality magnesium supplements, including magnesium glycinate and magnesium citrate, which are highly bioavailable and minimally likely to cause gastrointestinal distress. Their products are rigorously tested by third-party laboratories and are certified gluten-free, non-GMO, and vegan, ensuring purity and safety. For instance, their Magnesium Glycinate contains 120 mg of elemental magnesium per capsule and is available in various serving sizes, making it a versatile option for different needs. Pure Encapsulations' commitment to quality is evident in their NSF-registered facility and strict testing protocols for identity, potency, contaminants, and heavy metals. This brand is a trusted choice for those seeking effective and reliable magnesium supplementation.

Life Extension

Life Extension is a renowned brand that stands out for its high-quality magnesium supplements, including magnesium orotate, which is crucial for addressing the widespread magnesium deficiency affecting 68% of Americans. Their supplements are designed to support over 300 biochemical reactions in the body, including maintaining normal muscle and nerve function, heart rhythm, and bone health. Magnesium orotate from Life Extension is particularly valued for its solubility and bioavailability, making it an effective choice for therapeutic purposes. Studies have shown that magnesium supplementation can lead to significant health benefits, such as a 41% reduction in stroke risk and improved cognitive function. Life Extension's commitment to providing evidence-based supplements has made it a trusted source for those seeking to optimize their magnesium intake.

Thorne Research

Thorne Research is a highly regarded brand in the health and wellness industry, known for its rigorous quality standards and collaborations with prestigious institutions like the Mayo Clinic and Johns Hopkins. While Thorne Research does not specifically offer magnesium orotate, they do provide a range of highly bioavailable magnesium forms, such as magnesium glycinate, citrate, and malate, which are well-tolerated and effective. Established in 1984, Thorne Research has a long history of commitment to quality and transparency, as evidenced by their 100% Clean Policy and NSF Certified for Sport products. Their supplements are free from harmful ingredients and are trusted by top athletes and teams, including 11 U.S. Olympic National Teams. Thorne's products undergo stringent testing to ensure purity and bioavailability. For more information, visit the Thorne Research website.

Source Naturals

Source Naturals is renowned for its high-quality magnesium supplements, including magnesium bis-glycinate, though it does not specifically offer magnesium orotate. However, their magnesium bis-glycinate is highly effective, with each serving of two tablets providing 200 mg of magnesium, which is 48% of the Daily Value (DV). This formulation, chelated to the amino acid glycine, enhances absorption and usability by the body. Approximately 75% of Americans are estimated to be magnesium deficient, making supplements like those from Source Naturals crucial for maintaining optimal health. Their products are free from common allergens and additives, ensuring a safe and effective supplement option.

NutriCology

NutriCology is recognized as one of the top producers of magnesium orotate due to its commitment to quality and purity. This supplement is formulated to provide optimal bioavailability, with magnesium orotate being a highly absorbable form of magnesium, essential for over 300 enzyme systems in the body. Studies have shown that approximately 30% to 40% of dietary magnesium is typically absorbed, and magnesium orotate enhances this absorption rate. NutriCology ensures that their products meet stringent standards, making them a trusted choice among health professionals and consumers. With a focus on using high-quality ingredients, NutriCology's magnesium orotate supplements are designed to support heart health, muscle function, and overall well-being.

Douglas Laboratories

Douglas Laboratories is renowned for its high-quality magnesium supplements, including magnesium orotate, which is formulated to support various bodily systems such as the cardiovascular, muscular, and nervous systems. Magnesium orotate, as part of Dr. Hans Nieper's formulas, provides 1,000 mg of magnesium orotate per serving for individuals under 50 years old, translating to 63 mg of elemental magnesium, which is 15% of the Daily Value (DV). This supplement is highly absorbable and may help in carbohydrate metabolism and insulin response. Douglas Laboratories ensures that their products are made with bioavailable forms of magnesium, such as magnesium aspartate and chelated magnesium, which are well-tolerated and highly absorbed by the body. Their commitment to quality and scientific research makes them a trusted brand in the nutritional supplement industry.

Solaray

Solaray is a renowned brand for producing high-quality magnesium supplements, including magnesium orotate, which is highly valued for its heart health benefits and enhanced bioavailability. Their Magnesium Asporotate(tm) formula combines magnesium orotate with aspartate and citrate, ensuring 95% of the Daily Value per serving, which is 400 mg of magnesium. This blend supports strong bones, healthy muscles, and heart function, making it a comprehensive choice. Solaray's products are triple tested for purity and potency, ensuring reliability. With over 50% of the population not meeting daily magnesium requirements, Solaray's supplements are a significant aid in maintaining optimal health.