Top Picks for Knee Replacement Brands in 2023

Knee replacement surgery has become a crucial procedure for many individuals suffering from joint issues, offering a new lease on life. The efficacy of the surgery heavily depends on the quality of the prosthetics used, making the choice of brand quite vital. Renowned companies like Zimmer Biomet, Stryker, and DePuy Synthes are often celebrated for their innovation and reliability in producing high-quality knee replacement implants. To discover a curated list of some of the best knee replacement brands available today, see below.

Illustration of knee replacement

Best brands of knee replacement in 2025

Zimmer Biomet

Zimmer Biomet is a leading producer in the knee replacement market, dominating approximately 80% of the market share along with other major players like Stryker and DePuy Synthes. The company has seen a 10% increase in revenue in Q1 2023, with a 15% increase in knee implant sales, and is expected to achieve cementless knee market penetration of 50% or higher. Zimmer Biomet offers a comprehensive range of knee systems, including total, partial, and revision knee systems, as well as innovative products like the Persona Knee and the ROSA Knee System. Their Persona Knee system is designed for optimal fit and function, with features like anatomically accurate components and advanced materials such as Vivacit-E Vitamin-E Highly Crosslinked Polyethylene. The company's strong performance and innovative products position it as a key driver in the growing knee replacement market. For more detailed insights into their offerings, explore Zimmer Biomet's official product page.

DePuy Synthes

DePuy Synthes, a leading brand in orthopedic solutions, is renowned for its innovative knee replacement products, offering high-quality implants with a success rate of over 90% in long-term outcomes. Introduced in the 1960s, DePuy Synthes has continuously evolved its technology, such as the ATTUNE Knee System, which has been used in millions of procedures worldwide. Studies have shown that patients who receive DePuy Synthes knee replacements experience significant improvements in mobility and pain reduction, with some reports indicating up to 95% patient satisfaction. The brand's commitment to research and development has led to advancements like personalized knee implants, enhancing the precision and effectiveness of surgical procedures. With a global presence and a history spanning over six decades, DePuy Synthes remains a trusted name in orthopedic care.

Stryker

Stryker is a leading manufacturer of knee replacement implants, offering a comprehensive portfolio for primary and revision knee arthroplasty. Their flagship Triathlon Knee System has helped restore function and relieve pain for over 1 million patients since its launch in 2004. In 2023, Stryker's sales of knee-related products amounted to around $2.2 billion, highlighting their significant market presence. The company holds a 20% market share in the knee replacement market, which is expected to grow at a CAGR of 4.6% from 2024 to 2031. Stryker's commitment to innovation and quality has made it a trusted name in orthopedic surgery.

Smith & Nephew

Smith & Nephew is a leading manufacturer in the global knee replacement market, holding a significant 10% market share of hip and knee implants in 2023. The company, based in the UK, specializes in advanced medical equipment, including arthroscopy products and wound management solutions. In 2020, Smith & Nephew accounted for 11% of the global market share for hip and/or knee implants, demonstrating its strong presence in the orthopedic industry. With revenues of $5,212 million in 2021, the company continues to innovate and expand its offerings. Smith & Nephew's products are widely recognized for their quality and effectiveness in orthopedic surgeries. For more detailed information on the market share of worldwide hip and knee implants, you can visit this source.

Arthrex

Arthrex is a notable player in the knee replacement market, known for its innovative and reliable implant solutions. The company has issued recalls for its iBalance knee replacement line, including the iBalance Total Knee Arthroplasty System and the iBalance Unicondylar Knee Arthroplasty System, highlighting their commitment to quality and safety. Despite these recalls, Arthrex continues to innovate, responding to the demand for durable implants that can withstand higher levels of physical activity, particularly among younger patients undergoing knee replacement surgeries. However, the market dominance is largely held by other major players like Zimmer Biomet, Stryker, and DePuy Synthes, which collectively hold around 80% of the total market share. Arthrex's focus on developing advanced implants aligns with the growing need for long-term reliability in knee replacements.

Conformis

Conformis is a pioneering medical technology company renowned for its customized knee replacement implants, which are individually sized and shaped to fit each patient's unique anatomy. Since its inception, Conformis has sold over 50,000 of these personalized implants, leveraging its proprietary iFit Image-to-Implant technology to ensure superior clinical outcomes, including better function and greater patient satisfaction compared to traditional off-the-shelf implants. A clinical study published in 2022 found that 72.3% of patients preferred their Conformis personalized knee replacements over competitive off-the-shelf implants. This innovative approach has positioned Conformis as a leader in the orthopedic industry, offering a broad line of customized knee implants that restore the natural shape of a patient's knee. With a strong portfolio of approximately 500 issued patents and pending patent applications, Conformis continues to drive advancements in joint replacement technology.

B. Braun

B. Braun is a leading producer in the knee replacement market, renowned for its innovative and flexible implant options, such as the e.motion® knee endoprosthesis system, which offers high congruency and advantages in wear and kinematics. This system is compatible with various soft-tissue conditions and bone defects, enhancing operative efficiency and ergonomics. B. Braun's products, including those integrated with computer-aided operating techniques like OrthoPilot®, have been improving implant alignment for over 20 years. The company's contributions are significant in a market expected to grow at a CAGR of 5.1% from 2024 to 2032, with the global knee replacement market valued at USD 9.4 billion in 2023. B. Braun's products are part of a market dominated by a few key players, with market leaders holding approximately 80% of the total market share.

DJO Global

DJO Global is a leading provider of high-quality medical devices, particularly in the knee replacement market, with its EMPOWR Knee Platform offering a comprehensive suite of solutions including primary, cementless primary, complex primary, and tibial revision systems. The EMPOWR Porous(tm) Knee System and EMPOWR(tm) Complex Primary Knee System, launched in 2018, have significantly expanded the company's capabilities in treating a wide variety of patients. These systems utilize advanced technologies such as highly porous metals to enhance implant fixation and patient outcomes. DJO Global's products are widely used by orthopedic specialists and have contributed to the company's strong growth over the past few years. The efficiency of their instrument trays and streamlined instrumentation allows for up to 12 knee replacements in a single day, making them well-suited for both hospital and ambulatory surgery center environments.

Aesculap

Aesculap, a renowned brand under the B. Braun Company, is a significant player in the knee replacement market, known for its high-quality orthopedic products. Although as of April 1, 2024, Aesculap Implant Systems stopped sales of its orthopedic products in the United States, it continues to support existing patients with necessary components. The brand has been involved in various knee replacement technologies, including the E-motion knee, which has been frequently used in computer-navigated total knee replacement surgeries. Aesculap's products have contributed to the global knee replacement market, which is expected to grow at a CAGR of 5% from 2023 to 2032, reaching a market size of USD 16.6 billion by 2032. Despite the recent changes, Aesculap remains a key name in the industry due to its historical contributions and ongoing support. For more information, visit the Aesculap Implant Systems website.

Exactech

Exactech, a renowned leader in the orthopedic industry, is distinguished for its innovative and high-quality knee replacement solutions. The company's products, such as its Optetrak and Truliant knee systems, have garnered significant market attention due to their advanced materials and design, contributing to the global knee replacement market valued at USD 9.4 billion in 2023 and projected to grow at a CAGR of 5.1% from 2024 to 2032. Exactech's commitment to improving patient outcomes and its extensive range of orthopedic implants have made it a preferred choice among healthcare providers. The company's focus on research and development ensures continuous innovation, aligning with the increasing demand driven by rising obesity rates and the prevalence of osteoarthritis. As the market expands, Exactech is poised to maintain its strong position.