Top-Rated Saccharomyces Boulardii Brands for Optimal Gut Health

Saccharomyces boulardii, a beneficial yeast often used as a probiotic supplement, has gained popularity for its ability to support digestive health and balance gut flora. With an increasing demand for this probiotic, several brands have emerged, offering high-quality formulations that cater to different preferences and needs. From well-established names in the probiotic industry to newer companies focusing on innovative delivery methods, there's a wide array of options available for consumers looking to incorporate saccharomyces boulardii into their wellness routine. To explore the top-rated brands and find the best options for your health goals, we invite you to check out our comprehensive list below.

Illustration of saccharomyces boulardii

Best brands of saccharomyces boulardii in 2025

Florastor

Florastor is a leading brand in the saccharomyces boulardii market, known for its proprietary probiotic strain, Saccharomyces boulardii CNCM I-745, which has been clinically tested for over 60 years. This yeast-based probiotic actively stimulates immunity, survives antibiotics, and withstands the low pH environment of the stomach, making it highly effective in maintaining gut health. Florastor increases the production of Immunoglobulin A (IgA) and enhances digestive enzyme production, improving nutrient absorption. It is resistant to 16 common oral antibiotics and increases short-chain fatty acid levels by 60%, contributing to better energy levels. With its strong intestinal coverage and protection, Florastor is a preferred choice for those seeking a reliable probiotic supplement. For more information, visit the Florastor website.

Nature's Way

Nature's Way is a renowned brand for producing high-quality Saccharomyces boulardii supplements, known for their expert formulation that includes good gut bacteria and prebiotics. Their product combines Saccharomyces boulardii with five strains of Lactobacilli and Bifidobacteria, along with the unique Prebiotic FS2-60, enhancing the colonization of friendly flora and reducing unfriendly species. This formulation is crucial for maintaining a balanced gut microbiome, which is essential for overall health. The supplement is available in 30 capsules, each providing a 5 billion synbiotic daily blend of good bacteria. This comprehensive approach makes Nature's Way a trusted choice for those seeking probiotic therapy.

Jarrow Formulas

Jarrow Formulas is a renowned brand in the saccharomyces boulardii market, known for its high-quality probiotic and prebiotic products. Founded in 1977, Jarrow Formulas has established itself as a leader through innovative formulations and rigorous scientific research, earning numerous awards such as the Consumer Lab #1 Probiotics for Customer Satisfaction in 2019 and 2021. Their Saccharomyces Boulardii + MOS product combines probiotic yeast with prebiotics to support digestive health, featuring 5 billion CFU per serving. The company adheres to strict quality standards, including Current Good Manufacturing Practices (cGMP) and USDA Organic certifications. Jarrow Formulas' commitment to quality and innovation has made it a trusted name in the health supplement industry.

NOW Foods

NOW Foods is a renowned brand for producing high-quality Saccharomyces boulardii probiotics, known for their efficacy in supporting intestinal health and balancing gut flora. Their Saccharomyces boulardii supplements contain 5 billion CFU per capsule, which has been shown to reduce the duration of diarrhea by about 1 day and is recommended by the European Society of Paediatric Infectious Diseases and European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).

Garden of Life

Garden of Life is a renowned brand in the health food industry, particularly recognized for its high-quality probiotic formulas that include *Saccharomyces boulardii*. Their Primal Defense Ultra product is a broad-spectrum probiotic formula providing 15 billion live cells per daily serving, including 13 species of beneficial cultures. This formula supports normal bowel function, promotes a healthy immune system, and is packaged using the BioProtect(r) system to ensure optimum freshness and potency. With over 4 million bottles sold, Garden of Life's Primal Defense has established itself as a leading probiotic in the market. The brand's focus on digestive health and the use of Homeostatic(r) Soil Organisms (HSOs) sets it apart in the industry.

Pure Encapsulations

Pure Encapsulations is renowned for its high-quality Saccharomyces boulardii supplements, each capsule containing 5 billion live cells to support gastrointestinal health and maintain gut flora balance. With over 30 years of research and development, Pure Encapsulations ensures product purity and potency through third-party testing and rigorous quality control, sourcing premium raw materials from trusted suppliers worldwide. Their products are free from common allergens and unnecessary additives, and the manufacturing facility is NSF-GMP registered and exceeds US Pharmacopeia standards. This brand's commitment to transparency and quality has made it a trusted name in the health supplement industry. Pure Encapsulations' Saccharomyces boulardii has been shown to reduce the duration of diarrhea and hospitalization by about one day, highlighting its efficacy in clinical conditions.

Klaire Labs

Klaire Labs, now part of SFI Health, is a renowned producer of Saccharomyces boulardii, offering high-potency formulations with up to 5 billion CFUs per serving. This non-pathogenic, transient yeast has been used since its discovery in 1920 to support gastrointestinal health, promote healthy bowel transit time, and enhance immune response. Klaire Labs' products are hypoallergenic, free from common allergens like lactose, gluten, and soy, making them suitable for various dietary needs. The formulations are designed to be compatible with other probiotics and have been clinically tested for safety and efficacy in multiple gastrointestinal conditions. Klaire Labs ensures maximum potency and safety through certified ingredients and careful storage recommendations.

Seeking Health

Seeking Health is a prominent brand in the saccharomyces boulardii market, known for its high-quality probiotic supplements. Their Saccharomyces Boulardii product contains 5 billion beneficial organisms per serving, supporting bowel regularity and immune health. This acid-resistant and temperature-tolerant yeast is suitable for vegans and vegetarians and meets or exceeds cGMP quality standards. The product is available in 60 veg capsules per container and does not require refrigeration. With its robust formulation, Seeking Health's Saccharomyces Boulardii is a popular choice for maintaining a healthy digestive system.

Bio-Kult

Bio-Kult is a leading brand in the production of Saccharomyces boulardii supplements, known for its advanced formulation that combines live yeast culture with vitamin D to support the immune system and intestinal flora. Their product, Bio-Kult S. Boulardii, contains 5 billion CFU per 2 capsules and provides 120% of the daily recommended value of vitamin D. It is gluten-free, lactose-free, and suitable for vegetarians, making it a versatile and safe option. The global Saccharomyces boulardii market, in which Bio-Kult is a key player, is projected to grow at a CAGR of 6.24% from 2021 to 2028, reaching USD 10,949.73 million by 2028. Bio-Kult's formulation is backed by clinical research and can be used daily, even when traveling or alongside antibiotics.

Designs for Health

Designs for Health is a reputable brand known for producing high-quality Saccharomyces boulardii supplements, such as FloraMyces™. This product contains 500 mg or 10 billion viable cells per serving and is widely recognized for its efficacy in treating gastrointestinal disorders, including acute gastroenteritis and antibiotic-associated diarrhea. Studies have shown that Saccharomyces boulardii can reduce the duration of diarrhea and hospitalization by about one day. It is also recommended by the European Society of Paediatric Infectious Diseases and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) for its therapeutic benefits. With its strong antioxidant capacity and stress tolerance, Designs for Health's FloraMyces™ is a trusted choice for supporting gastrointestinal health. For more information, visit their patient education page on FloraMyces™.