Top Probiotic Brands You Need to Know About

In the quest for optimal gut health, many individuals have turned to probiotics as a natural solution to support their digestive systems and overall well-being. With the growing popularity of probiotic supplements, several brands have emerged as leaders in the market, offering high-quality products backed by scientific research and customer satisfaction. These top brands stand out for their innovative formulations, commitment to purity, and proven efficacy in promoting healthy microbiomes. To explore the list of the best probiotic brands and discover which could be the right fit for your health needs, continue reading below.

Illustration of probiotics

Best brands of probiotics in 2025

Align

Align is a prominent brand in the probiotics market, known for its high-quality probiotic products that support digestive health and overall well-being. The brand is part of the broader probiotics market, which was valued at USD 5.54 billion in 2022 and is anticipated to grow at a CAGR of over 8.1% from 2023 to 2032. Align's products are often recommended by healthcare professionals, reflecting the trust in their efficacy. In the U.S., the probiotics market, including brands like Align, benefits from increasing consumer awareness of gut health and its impact on overall health. The brand's popularity is also driven by the growing preference for preventive healthcare and innovative delivery methods. For more information on Align's products, visit their official website.

Culturelle

Culturelle is renowned as one of the best producers of probiotics, leveraging the clinically proven effectiveness of the Lactobacillus rhamnosus GG (LGG®) strain, which has been studied in over 1,000 scientific studies and 30 years of research. This single-strain super probiotic is trusted for its ability to survive harsh stomach acids and support a strong barrier against non-beneficial bacteria. Culturelle products are designed to promote digestive health and overall well-being, with formulations that are vegetarian, non-GMO, and gluten-free. The brand ensures maximum potency and efficacy through innovative packaging that protects the probiotics from light, oxygen, and moisture. Culturelle is recommended by pediatricians and is suitable for the entire family. For more information, explore their digestive health solutions.

Renew Life

Renew Life is a leading brand in the probiotics market, known for its innovative and science-based gut wellness solutions. With over 25 years of experience, Renew Life has pioneered superior-quality digestive wellness supplements, including probiotics, fiber, digestive aids, and enzymes. Their products, such as the Ultimate Flora Probiotics, combine billions of active cultures with organic prebiotic fiber, enhancing gut health and overall well-being. Renew Life is part of The Clorox Company, a multinational manufacturer with a strong presence in the consumer and professional products market. The brand's commitment to quality and innovation has made it a trusted name in the health and wellness industry. For more information, visit Renew Life's official website.

Garden of Life

Garden of Life is a renowned brand in the probiotics market, known for its high-quality and diverse range of probiotic products. The company is part of the broader probiotics industry, which is expected to reach $78.91 billion by 2024 and grow at a CAGR of 7.53% from 2024 to 2029. Garden of Life's products, such as their RAW Probiotics line, offer targeted probiotic intake, contributing to the 14% market share held by probiotic supplements. The brand's commitment to using multiple strains and high CFU (Colony-Forming Units) counts aligns with consumer demand for effective probiotic solutions. As the probiotics market continues to expand, brands like Garden of Life are poised to benefit from the increasing global demand. For more information about their probiotics, visit the official Garden of Life website.

Bio-Kult

Bio-Kult, a leading brand in the probiotics market, is renowned for its high-quality probiotic supplements, particularly its multi-strain live bacteria product which contains 14 different strains, making it one of the most complex probiotic supplements available. Founded by Probiotics International Limited (Protexin), Bio-Kult has over 20 years of experience in manufacturing live bacteria products. The brand has seen significant growth, especially with its marketing strategy implementation in regions like Romania, resulting in a constant increase in orders quarter by quarter. Bio-Kult is recognized as Great Britain's #1 probiotic brand, according to Kantar FMCG purchase panel data as of 2023. The brand offers various products, including Bio-Kult Everyday, Bio-Kult Boosted, and Bio-Kult Infantis, with promotional offers such as up to 20% off and free gifts.

Klaire Labs

Klaire Labs is a reputable brand in the probiotics market, known for its high-quality and scientifically-backed probiotic supplements. Their products are carefully formulated with specific strains of bacteria selected for their ability to provide targeted health benefits, ensuring the probiotics survive the harsh conditions of the gastrointestinal tract. Klaire Labs' commitment to quality and potency is evident through rigorous testing and innovative packaging that protects against moisture, light, and other environmental factors. Their products are manufactured in state-of-the-art facilities adhering to strict quality control standards, making them a trusted choice in the market. As part of the growing probiotics industry, Klaire Labs contributes to the segment that is expected to grow at a CAGR of 14.8% from 2024 to 2030. For those curious about storage requirements, you can learn more about whether Klaire Labs probiotics need to be refrigerated.

Hyperbiotics

Hyperbiotics is renowned as one of the top producers of probiotics, offering high-potency formulas that support digestive and immune health. Their Prebiotic + Probiotic 60 Billion CFU product includes five targeted probiotic strains, such as Lactobacillus plantarum and Lactobacillus acidophilus, and is enhanced with 100mg of prebiotic fructooligosaccharides (FOS) to maximize benefits. The acid-resistant capsules ensure the probiotics survive harsh stomach acids, reaching the intestinal tract alive. This formulation is designed to reduce bloating and support overall gut health, with 80% of the immune system benefiting from the gut microbiome. The product is available for daily use, with a minimum of 15 billion CFU guaranteed at expiration.

Seed

Seed Health is a leading brand in the probiotics market, known for its clinically-studied products that impact both human and planetary health. Its flagship product, the DS-01(r) Daily Synbiotic, combines 24 different probiotic strains and prebiotics, making it significantly more effective than many other probiotics. Founded in 2015 by Ara Katz and Raja Dhir, Seed Health is projected to generate around $200 million in revenue in 2024, up from $140 million the previous year. The company's products are engineered to be environmentally friendly, eliminating the need for refrigeration and blister packs, and are packaged in compostable and recyclable materials. Seed Health's commitment to sustainability and scientific validation has made it a standout in the probiotics industry.

Dr. Ohhira’s

Dr. Ohhira's Probiotics is a renowned brand in the probiotic market, known for its all-natural, superior probiotic formula developed to support digestive comfort, nutrient absorption, and a healthy immune system. The probiotics are fermented for three years using mountain spring water, fruits, vegetables, and 12 distinctive strains of lactic acid bacteria, ensuring a rich culture medium that includes prebiotics, probiotics, and postbiotics. This brand is particularly notable for its non-GMO, hypoallergenic, and vegetarian products, free from dairy, gluten, and artificial ingredients. Dr. Ohhira's Probiotics have been recognized for over 30 years and do not require refrigeration, with a three-year shelf life. Natural and specialty stores, which hold a 45% market share of probiotic sales, often feature Dr. Ohhira's products.

Florastor

Florastor is a leading brand in the probiotics market, renowned for its #1 selling probiotic worldwide, which utilizes the unique strain *Saccharomyces boulardii* CNCM I-745(r) to flush out bad gut bacteria and boost good bacteria, supporting immune health and protecting against multiple GI issues. The global saccharomyces boulardii market, in which Florastor is a key player, is projected to grow at a CAGR of 6.6% from 2024 to 2031, with the global market size estimated at USD 7154.6 million in 2024. Florastor's products are gluten-free, vegetarian, and non-GMO, catering to a wide range of consumers. The brand's success is part of the broader probiotics market, which is expected to reach USD 115.07 billion by 2029, growing at a CAGR of 8.39%. Florastor's dual-action probiotic supplement is particularly popular for its ability to maintain a balanced and resilient gut.