Top PQQ Brands Worth Exploring for Optimal Health

In recent years, Pyrroloquinoline Quinone (PQQ) has gained popularity as a supplement for its potential benefits in energy production and cognitive health. As consumers seek quality products, several brands have emerged as leaders in the PQQ market, each offering unique formulations and manufacturing processes. Some of the best brands ensure that their PQQ supplements are made with non-GMO ingredients, support sustainable practices, and undergo rigorous third-party testing to guarantee potency and purity. To discover a comprehensive list of these top brands and what makes them stand out, continue reading below.

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Best brands of pqq in 2025

Jarrow Formulas

Jarrow Formulas is a leading producer of PQQ (pyrroloquinoline quinone) supplements, known for their high-quality and scientifically-backed products. Their PQQ supplements, available in 10mg and 20mg capsules, support mitochondrial biogenesis, protect mitochondria from oxidative stress, and promote efficient cellular energy production and heart health. The company ensures purity and potency by adhering to Current Good Manufacturing Practices (cGMP) and collaborating with global researchers. Jarrow Formulas' commitment to superior science and funding studies enhances the efficacy of their formulations. Their products are free from major allergens such as wheat, gluten, soybeans, and dairy.

Doctor's Best

Doctor's Best is a renowned brand for producing high-quality PQQ supplements, leveraging science-based nutrition to support mitochondrial function, cognitive health, and cellular energy. Their PQQ formulas, such as the one featuring 20 mg of Pyrroloquinoline Quinone per serving, are enhanced with BioPerine to increase bioavailability by up to 95% Piperine content. These supplements are non-GMO, gluten-free, and vegan, making them accessible to a wide range of consumers. Doctor's Best ensures purity and potency, as seen in their High Absorption CoQ10 + PQQ formula, which also includes 100 mg of Coenzyme Q10 per serving. This synergistic combination helps protect the central nervous system and promotes the production of new mitochondria. You can find more about their high-quality PQQ supplements online.

Life Extension

Life Extension is a renowned brand for producing high-quality PQQ (pyrroloquinoline quinone) supplements, known for promoting the growth of new cellular mitochondria, which is crucial for maintaining youthful cellular energy. Their PQQ capsules support mitochondrial biogenesis, provide powerful antioxidant protection, and help protect delicate mitochondrial DNA. Preclinical research has shown that PQQ can increase lifespan by an average of 30% in roundworms and has various benefits including reducing blood sugar and cholesterol, and defending against kidney and liver damage. Life Extension's PQQ supplements are manufactured using a bacterial fermentation process and are available in 10 mg, 30 vegetarian capsules. This supplement is part of an anti-aging strategy, supporting heart health, cognitive health, and overall well-being.

Pure Encapsulations

Pure Encapsulations is a renowned brand for producing high-quality PQQ supplements, such as their SR-CoQ10 with PQQ, which offers 24-hour sustained release support for cardiovascular, neural, and cognitive health. With over 30 years of research and development, Pure Encapsulations ensures their products are free from unnecessary additives and common allergens, and are manufactured in an NSF-GMP registered facility. Their PQQ supplements, like BioPQQ(r), are produced in Japan using a patented natural fermentation process. Each product is third-party tested to ensure purity and potency, and the brand sources premium raw materials from trusted suppliers worldwide. This commitment to quality and transparency makes Pure Encapsulations a trusted choice for health enthusiasts.

Now Foods

Now Foods is renowned for its high-quality supplements, including its PQQ Energy product, which combines Pyrroloquinoline Quinone (PQQ) with other essential nutrients like CoQ10 and Acetyl-L-Carnitine to support mitochondrial health and cognitive function. Each serving of PQQ Energy contains 20mg of BioPQQ(r), 30mg of CoQ10, and 200mg of Acetyl-L-Carnitine, along with 1,000mcg of Vitamin B-12, making it a comprehensive support for cellular energy production. This formulation is particularly beneficial for organs with high energy demands, such as the heart and brain. Now Foods ensures its products are manufactured in a GMP facility, guaranteeing quality and purity. With a long history of providing natural health products, Now Foods has established itself as a trusted brand in the supplement industry.

Source Naturals

Source Naturals is a renowned brand in the health supplement industry, particularly noted for its high-quality PQQ (Pyrroloquinoline Quinone) products. Established in 1982, Source Naturals has been a pioneer in immune support and overall wellness, with products like PQQ Mind™ and PQQ Healthy Aging™ that support mitochondrial biogenesis, cognitive function, and energy levels. Their PQQ supplements are free from common allergens such as yeast, dairy, egg, gluten, corn, soy, and wheat, and are available in various tablet options. The brand's commitment to using active forms of ingredients ensures better metabolism by the body. With an 18-time Vity Award for Best Immune Support, Source Naturals stands out as a trusted name in the health supplement market.

Solgar

Solgar, a renowned brand in the supplement industry since 1947, is committed to quality and innovation, making it a trusted producer for various nutritional supplements, although it is not specifically highlighted for PQQ production. Solgar is owned by Nestle Health Science, which acquired it in 2021 along with other brands like Nature's Bounty and Garden of Life. Known for its high-quality ingredients and small-batch manufacturing in New Jersey, Solgar ensures consistency and reliability in its products. While Solgar's portfolio includes a wide range of vitamins and minerals, its commitment to whole-health support is evident in its diverse product line. However, specific PQQ products are not a primary focus of Solgar's offerings. For more information, visit their supplement offerings.

Swanson Health Products

Swanson Health Products is a renowned brand in the health supplement industry, particularly noted for its high-quality PQQ (Pyrroloquinoline Quinone) products. Founded in 1969 by Leland Swanson Sr., the company has grown to offer over 26,000 products, including its Swanson Ultra PQQ, which provides 10 mg of PQQ per serving. Swanson Health Products ensures stringent quality control through independent third-party audits and testing by ConsumerLab.com. The company has expanded globally, with assistance from the U.S. Commercial Service, and has maintained a strong reputation for purity, potency, and safety. Since 2001, Swanson Health Products has participated in Good Manufacturing Practices (GMP) audits to ensure the highest standards.

Thorne Research

Thorne Research is renowned for its high-quality supplements, including Pyrroloquinoline Quinone (PQQ), which is backed by scientific research to support mitochondrial health and energy production. Thorne's formulations are designed to optimize cellular function, with PQQ playing a crucial role in increasing mitochondrial biogenesis and reducing oxidative stress. Since its establishment, Thorne has maintained a commitment to using only the purest ingredients, ensuring a high standard of efficacy and safety. Their products are often recommended by healthcare practitioners due to their rigorous testing and adherence to good manufacturing practices. For those seeking a reliable source of PQQ, Thorne Research stands out as a trusted brand.

Garden of Life

Garden of Life, although primarily known for its CoQ10 supplements, is also recognized for its holistic approach to nutrition, which could potentially benefit the production and formulation of PQQ (Pyrroloquinoline Quinone) supplements. Their manufacturing process involves complex mixtures of fruits, vegetables, and other natural elements to mimic natural dietary sources, which can enhance the bioavailability and effectiveness of nutrients like PQQ. Garden of Life's supplements often include probiotic blends and raw cold-pressed oils to improve absorption, a strategy that could be advantageous for PQQ supplementation. However, specific studies on Garden of Life's PQQ formulation are not available, but their approach to using natural and complex ingredient profiles aligns well with the principles of enhancing mitochondrial function and biogenesis supported by PQQ. Given their reputation for quality and customer satisfaction, Garden of Life could be a reliable choice for those seeking a PQQ supplement. For more information, visit their official website.