In recent years, the demand for high-quality MSM supplements has surged due to their potential health benefits, particularly in joint health and mobility. Many reputable brands have risen to prominence, offering pure and potent MSM products tailored to varying consumer needs. With a mix of powder and capsule options, these brands are celebrated for their commitment to transparency, sourcing, and third-party testing. To explore a curated list of the best MSM supplement brands available today, continue reading below.
Illustration of msm supplement
Best brands of msm supplement in 2025
Doctor's Best
Doctor's Best is a renowned brand in the health supplement industry, particularly for its high-quality MSM (methylsulfonylmethane) products. Their MSM formulas, such as those with OptiMSM, are designed to support joint comfort and mobility, as well as the health of hair, skin, and nails. Each serving of their MSM supplements, available in various forms like tablets and powder, contains a significant amount of beneficial sulfur, with some products offering up to 3,000 mg per serving. These supplements are non-GMO, gluten-free, and vegan-friendly, ensuring they cater to a wide range of dietary needs. With a commitment to science-based nutrition, Doctor's Best ensures the freshness and efficacy of their products. For more information, visit the official Doctor's Best MSM page.
NOW Foods
NOW Foods is renowned as one of the best producers of MSM supplements, offering a range of products that support healthy cartilage and joint health. Their MSM Powder and capsules, such as the MSM 1000 mg Veg Capsules, are popular choices for promoting joint mobility and overall well-being. These supplements are made from high-quality MSM, a sulfur-bearing compound naturally present in small amounts in fruits, vegetables, and grains. NOW Foods ensures strict quality control and adherence to dietary supplement standards, making their products a trusted choice among health enthusiasts. With a commitment to natural and effective ingredients, NOW Foods has established itself as a leader in the supplement industry. For more information on their MSM Powder, visit their official website.
Jarrow Formulas
Jarrow Formulas is a renowned brand in the MSM supplement market, known for its high-quality and scientifically-backed products. Since its inception in 1977, Jarrow Formulas has been committed to innovative research, funding studies on its products like Bone-Up and Co-Q10 Ubiquinol, and adhering to strict Current Good Manufacturing Practices (cGMP). The company has garnered 37 awards for its supplements, including the Consumer Lab #1 Probiotics for Customer Satisfaction in 2019 and 2021. Jarrow Formulas' MSM supplements, such as the 1000 mg veggie capsules and 1000g powder, are organic, non-GMO, and gluten-free, making them a preferred choice for those seeking joint health and skin support. With a strong focus on quality assurance and scientific research, Jarrow Formulas continues to be a leader in the health supplement industry.
OptiMSM by Kala Health
OptiMSM by Kala Health is renowned for its exceptional quality, with each tablet or capsule containing 1000 mg of 99.9% pure Methylsulfonylmethane (MSM), produced in the USA using a patented multi-stage distillation process to ensure purity and consistency. This supplement is vegan-friendly, gluten-free, and Kosher & Halal certified, making it suitable for a wide range of consumers. OptiMSM is backed by numerous pre-clinical and clinical studies and is recommended for joint health, skin, hair, and nail maintenance, as well as therapeutic pain relief. The dosage can be adjusted from 1-2 grams daily to 4-6 grams over a few weeks for optimal benefits. Kala Health's OptiMSM products are manufactured according to HACCP standards and are third-party tested to guarantee quality. Discover more about OptiMSM products by Kala Health.
Nature's Way
Nature's Way is a prominent player in the MSM supplement market, known for its high-quality products. In 2023, the MSM Capsule segment, which includes products from Nature's Way, accounted for a significant share of the global MSM Supplement market and is projected to experience substantial growth in the near future. The brand is part of a market expected to reach USD $10 billion by 2024, with a CAGR of 7%. Nature's Way, along with other key companies like Now Food and Source Naturals, is focusing on strengthening its product portfolio and expanding its business globally. The Retail Pharmacy segment, where Nature's Way products are widely available, is expected to expand significantly during the forecast period. For more details about their MSM supplements, visit their official product page.
Solgar
Solgar is a renowned brand in the MSM supplement market, known for its high-quality products that support bone and joint health, as well as healthy skin aging. Their MSM 1000 mg Tablets, containing OptiMSM(r), are particularly popular for reducing the appearance of fine lines and wrinkles. Solgar's products are part of a market that is expected to grow significantly, with the global MSM supplement market projected to experience a notable compound annual growth rate (CAGR) from 2024 to 2031. The brand's commitment to using premium ingredients like OptiMSM(r) has helped it maintain a strong market share, especially in the retail pharmacy segment, which is expected to expand significantly during the forecast period. Solgar's presence in the market is further bolstered by its inclusion among key competitors such as NOW Foods and Jarrow Formulas.
Source Naturals
Source Naturals is a renowned brand in the MSM supplement market, known for its high-quality products that are free from sugar, starch, salt, preservatives, and artificial additives. The brand's MSM supplements are rich in natural ingredients, making them a preferred choice for health-conscious consumers. As part of the growing MSM market, which is expected to reach a valuation of $389 million by 2033 with a CAGR of 5.5%, Source Naturals continues to expand its product portfolio to meet increasing demand. The brand's commitment to natural and organic products aligns with consumer preferences, driving its market growth. Source Naturals, along with other key players like Now Food and Doctor's Best, is a significant contributor to the global MSM supplement market.
Pure Encapsulations
Pure Encapsulations is renowned for producing high-quality MSM supplements, offering 99.7% pure, patented MSM (methylsulfonylmethane or dimethylsulfone) that contains 34% elemental sulfur, crucial for maintaining healthy tissues. Their MSM supports joint, immune, and respiratory health, and is synthetically derived from the OptiMSM® brand. Recommended dosages range from 1700-6800 mg per day, taken with meals. The product is free from unnecessary additives and common allergens, making it suitable for those with dietary restrictions. Pure Encapsulations' MSM has been backed by verifiable science, including studies published in reputable journals such as "Life Sci" and "Osteoarthritis Cartilage".
Life Extension
Life Extension is a renowned brand in the supplement industry, particularly for its high-quality MSM (methylsulfonylmethane) supplements. Since 1980, Life Extension has been dedicated to healthy aging, leveraging the latest scientific research to formulate their products. Their MSM supplements are produced in GMP-certified facilities, ensuring purity and efficacy, and are free from contaminants like heavy metals and microbiology. Each capsule contains 1000 mg of MSM, supporting joint health, muscle comfort, and inhibiting oxidative stress, with clinical trials demonstrating its effectiveness in promoting joint mobility and function. With a strong customer recommendation rate of 98%, Life Extension stands out as a trusted provider of MSM supplements.
Thorne Research
Thorne Research is renowned for producing high-quality MSM supplements, such as their Joint Support Nutrients, which combine MSM with other potent ingredients like glucosamine, curcumin, and boswellia to support joint health. This comprehensive formula includes 850 mg of MSM per serving, helping to maintain the structure of connective tissue and reduce joint pain and inflammation. Thorne Research adheres to strict standards for purity and potency, ensuring maximum bioavailability of the ingredients. Their products are professional-grade and gluten-free, making them a reliable choice for those seeking effective joint support. With a serving size of 4 capsules, this supplement is designed to be taken one to two times daily for optimal benefits.
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