Top MSM Brands for Optimal Wellness and Health Benefits

Choosing the right brand for MSM (methylsulfonylmethane) supplements can significantly impact your health journey, as quality and formulation differ widely across the market. With a surge in popularity, more brands are dedicating themselves to ensuring purity and efficacy, backed by rigorous testing and sustainable sourcing. Some of the top contenders have consistently garnered positive customer reviews and high ratings, suggesting they meet the expectations of transparency and potency. For a detailed exploration of the best MSM brands available today, take a look below.

Illustration of msm

Best brands of msm in 2025

Doctor's Best

Doctor's Best is a renowned brand for producing high-quality MSM (methylsulfonylmethane) supplements, utilizing OptiMSM(r), a 99.9% pure concentration of MSM that surpasses USP monograph standards through rigorous testing by independent laboratories. Their MSM formulas support joint comfort, mobility, and the health of hair, skin, and nails, and are available in various forms, including tablets and capsules, with servings ranging from 1,500 mg to 3,000 mg per dose. The products are non-GMO, gluten-free, and vegan, ensuring they cater to a wide range of dietary needs. Each batch is guaranteed for quality potency, and the brand emphasizes science-based nutrition. Doctor's Best MSM products are widely available and recommended for their beneficial sulfur content.

Now Foods

Now Foods is a leading producer of MSM supplements, known for their high-quality products that support joint health and connective tissue. Their MSM powder, for instance, is tested to contain a minimum of 99.7% purity, making it a reliable choice for those seeking to maintain healthy cartilage and skin. Available in various forms such as capsules and powder, Now Foods' MSM products are free from common allergens like yeast, wheat, gluten, and soy. The company's commitment to quality is evident in their GMP-certified manufacturing processes. Since its research began in 1979, MSM has been a staple in the health supplement industry, and Now Foods continues to innovate and expand its product line. For detailed product information, you can explore their MSM Healthy Skin Liposome Lotion.

Jarrow Formulas

Jarrow Formulas is a renowned brand in the supplement industry, particularly recognized for its high-quality MSM (Methylsulfonylmethane) products. Their MSM is an organic source of bioavailable sulfur, essential for producing glycosaminoglycans like chondroitin sulfate and hyaluronic acid, which are crucial for joint cartilage and skin health. Jarrow Formulas' commitment to superior science and quality ingredients has earned them significant consumer trust, as evidenced by their #1 ranking in customer satisfaction for probiotics in 2019, based on a survey of 10,931 responses from ConsumerLab.com subscribers. Their products are free from common allergens like wheat, gluten, and soybeans, making them suitable for vegetarians and vegans. The brand's dedication to purity and potency ensures that their MSM powder meets the highest standards of Current Good Manufacturing Practices (cGMP). For more details about their MSM powder, you can visit their official product page.

Nature's Way

Nature's Way is a renowned brand in the health supplement industry, particularly recognized for its high-quality MSM (Methylsulfonylmethane) products. Their MSM supplements, such as the 1,000 mg tablets, are formulated with OptiMSM®, the world's purest and most advanced form of MSM, ensuring optimal joint health and connective tissue maintenance. These products are gluten-free, vegan, and free from sugar, salt, yeast, wheat, corn, soy, dairy products, artificial colors, flavors, and preservatives. Nature's Way MSM is carefully tested to meet superior quality standards, making it a trusted choice for those seeking joint health support. With a long history of producing reliable supplements, Nature's Way continues to be a leader in the health and wellness market. For more information, you can explore their products on their dedicated product page.

Solgar

Solgar is renowned as one of the top producers of MSM (methylsulfonylmethane) supplements, offering high-quality products that support joint health, skin aging, and overall wellbeing. Their MSM 1000 mg tablets, made with naturally sourced ingredients, are recommended by 98% of consumers, as per a Global Praxis online shopper survey in 2017. These tablets contain OptiMSM(r), which is essential for producing glucosamine, a key component for bones and joints. Solgar's commitment to excellence, innovating since 1947, ensures their products meet the industry-recognized "Gold Standard." The tablets are vegan, vegetarian, kosher, and halal, and are free from sugar, salt, and starch.

Source Naturals

Source Naturals is a reputable brand known for producing high-quality MSM (methylsulfonylmethane) products, utilizing advanced technologies like liposome delivery for enhanced skin penetration. Their MSM Cream contains 13% MSM, along with antioxidants like vitamin E and ginkgo, to support healthy skin. The brand also offers MSM in powder and tablet forms, such as the OptiMSM powder, which is free from common allergens and artificial ingredients. Source Naturals' products are designed to replenish the body's sulfur supply, supporting joint health, skin clarity, and reducing inflammation. With a commitment to quality and purity, Source Naturals has established itself as a trusted name in the health supplement industry.

Pure Encapsulations

Pure Encapsulations is a renowned brand for producing high-quality MSM (methylsulfonylmethane) supplements, formulated with 99.7% pure, patented MSM and containing 34% elemental sulfur. With over 30 years of research and innovation, Pure Encapsulations ensures their products are free from unnecessary additives, common allergens, and GMOs. Their MSM supplements support connective tissue health, promote immune and respiratory function, and are essential for collagen, keratin, and protein metabolism. Available in both capsule and powder forms, these supplements are hypoallergenic and vegan-friendly. Pure Encapsulations' commitment to verifiable science and high-quality ingredients makes them a trusted choice.

Swanson

Swanson is renowned as one of the best producers of MSM (methylsulfonylmethane) supplements, offering high-quality products that support joint health, cartilage, tendons, and skin. Their MSM supplements, such as Swanson Ultra MSM, come in various strengths, including 1000 mg and 1500 mg formulations, ensuring there is an option for every need. These products are tested for purity, potency, and safety by both internal and third-party labs, adhering to Swanson Health's stringent quality standards. The TruFlex® MSM, a registered trademark of Swanson Health Products, is biologically active for easy assimilation. With a commitment to quality and wellness, Swanson has established itself as a trusted brand in the health supplement industry.

Natrol

Natrol is a prominent brand in the methylsulfonylmethane (MSM) supplement market, known for its high-quality products that support joint comfort and promote healthy joints and cartilage. MSM from Natrol helps provide the body with sulfur, a crucial mineral for building collagen and other connective tissues. The global MSM market, in which Natrol is a key player, is projected to grow at a CAGR of 5.5% from 2023 to 2033, reaching a valuation of US$ 389 million by 2033. Natrol's MSM supplements are part of a larger market trend where consumers increasingly seek natural and organic products, driving growth in regions like North America, which held a market size of US$ 85.08 million in 2022. By choosing Natrol, consumers can trust in a brand that is committed to using clean ingredients and non-GMO materials.

Thorne Research

Thorne Research is renowned as one of the top producers of MSM (methyl sulfonyl methane) supplements, known for their high-quality and pure ingredients. With over 30 years in the dietary supplement industry, Thorne Research has set a benchmark for purity and potency, earning approval from Australia's Therapeutic Goods Administration, a distinction no other U.S.-based dietary supplement producer has achieved. Their Joint Support Nutrients supplement combines MSM with glucosamine, boswellia, and curcumin to provide comprehensive joint health support. This formula includes 850 mg of MSM per serving, along with other key nutrients to enhance joint integrity and mobility. Thorne Research's commitment to quality and innovation has led to significant growth, with a 27.7% year-over-year increase in net sales to $63.0 million in 2022.