Top MSM Powder Brands for Optimal Health Benefits

When it comes to health supplements, MSM (Methylsulfonylmethane) powder has gained popularity for its potential benefits, including joint health and inflammation reduction. With numerous brands vying for consumers' attention, it can be challenging to determine which ones truly deliver quality and effectiveness. We've conducted thorough research and compiled a list of the top brands that stand out for their purity, potency, and customer satisfaction. Curious to find out which MSM powder brands made the cut? Read on to discover our recommendations.

Illustration of msm powder

Best brands of msm powder in 2025

NOW Foods

NOW Foods is a leading producer of MSM powder, known for its high-quality and pure methylsulfonylmethane products. Their MSM powder is free from common allergens such as yeast, wheat, gluten, soy, and nuts, and is produced in a GMP-certified facility. Each serving of NOW Foods MSM Powder contains 1.8 grams (1,800 mg) of MSM, with approximately 126 to 252 servings per container depending on the size. The product is recommended to be taken 1 to 2 times daily in juice or other liquid, with a caution to consult a physician if pregnant, nursing, or having a medical condition. NOW Foods has been a trusted brand in the health supplement industry since 1968.

Doctor's Best

Doctor's Best is a renowned brand for producing high-quality MSM powder, particularly their MSM Powder with OptiMSM, which is backed by numerous clinical studies for safety and efficacy. This product supports joint health, mobility, and the formation of healthy connective tissues, while also promoting the health of hair, skin, and nails due to its sulfur content. The formula is non-GMO, gluten-free, soy-free, and vegan, making it accessible to a wide range of consumers. Each serving size of 3 scoops (~3 grams) contains 3,000 mg of MSM, with approximately 83 servings per 8.8 oz (250 g) container. Available since 2007, this product has been a staple in the supplement market for over 15 years.

Nature's Way

Nature's Way is renowned as one of the top producers of MSM powder, known for its high-quality and pure products. In 2023, the MSM Capsule segment, which includes Nature's Way products, accounted for a significant share of the global MSM Supplement Market and is projected to experience substantial growth in the near future. Nature's Way's MSM supplements, such as OptiMSM, are recognized for their purity and lack of excipients. The brand's products are widely available in retail pharmacies and online, contributing to their expanding market presence. With a strong focus on quality and customer satisfaction, Nature's Way continues to strengthen its product portfolio and expand its global market share.

Jarrow Formulas

Jarrow Formulas is a renowned brand in the dietary supplement industry, particularly noted for its high-quality MSM (Methylsulfonylmethane) powder. Founded in 1977 in Los Angeles, Jarrow Formulas has over 40 years of experience in producing innovative and efficacious formulations based on sound scientific research. Their MSM powder is an organic source of bioavailable sulfur, essential for producing glycosaminoglycans like chondroitin sulfate, dermatan sulfate, and hyaluronic acid, which are crucial for joint cartilage and skin health. The product is free from common allergens such as wheat, gluten, soybeans, dairy, and nuts, making it suitable for a wide range of consumers. Jarrow Formulas ensures the purity and potency of their products by adhering to Current Good Manufacturing Practices (cGMP).

Kala Health

Kala Health is renowned as one of the best producers of MSM powder, particularly through their OptiMSM(r) brand, which is manufactured in the USA by Bergstrom Nutrition. OptiMSM(r) is distinguished by its 100% pure MSM content, achieved through a quadruple distillation process that ensures virtually no impurities. This high-purity MSM is easily absorbed by the body and is suitable for vegetarians and vegans. The product is available in various packaging options, including 250 grams, 500 grams, 1 kg, and 5 kg, each coming with a convenient measuring scoop. With a purity of over 99.9%, OptiMSM(r) stands out for its quality and consistency.

BulkSupplements

BulkSupplements is renowned as one of the best producers of MSM powder, offering a high-quality, gluten-free, and additive-free product. Their MSM powder is a top seller, supporting joint health, skin integrity, hair growth, and detoxification processes, with antioxidant properties to protect cells from free radicals. The product is available in various quantities, including a 1 kilogram pack, and has received positive reviews from customers who have used it for over 20 years to alleviate joint pain and inflammation. BulkSupplements ensures fast shipping, with 2-day delivery to 99.4% of the USA and international delivery times ranging from 4-10 days. The product is free of added sugar, soy, dairy, and gluten, making it a versatile and safe choice for various dietary needs.

H2O Air Water Americas

H2O Air Water Americas is recognized as a notable producer of MSM powder, although specific data on their market share or production volumes is not provided in the available sources. The global MSM supplement market, which includes MSM powder, is expected to experience significant growth, with the MSM Capsule segment accounting for a noticeable share in 2023 and projected to grow further. Key companies like Now Food and Source Naturals are focusing on strengthening their product portfolios. The retail pharmacy segment is anticipated to expand at a significant CAGR during the forecast period. However, detailed performance metrics for H2O Air Water Americas specifically are not disclosed. For further insights on the MSM supplement market, you can refer to the comprehensive market report.

Healthy Origins

Healthy Origins is renowned as one of the best producers of MSM powder, offering a high-quality supplement that is 99.9% pure and free of fillers, artificial ingredients, and allergens. Since its inception, the brand has maintained strict quality control, ensuring each batch meets or exceeds industry standards. Healthy Origins MSM powder is often recommended by health professionals for its potential benefits in joint health and inflammation reduction. The product is manufactured in a cGMP-certified facility, guaranteeing consistency and safety. With a commitment to transparency, Healthy Origins provides detailed labeling and third-party testing results.

Swanson

Swanson Vitamins is renowned for producing high-quality MSM powder, with products like NOW Foods MSM Powder that are free from common allergens such as yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish, and tree nuts. Each serving of NOW Foods MSM Powder contains 1.8 grams (1,800 mg) of MSM, with no other ingredients added. The product is manufactured in a GMP-certified facility, ensuring strict quality standards. The suggested usage is 1/2 teaspoon 1 to 2 times daily, and the product is available in various sizes, including 1-pound and 8-ounce containers. This attention to detail and commitment to purity make Swanson a trusted brand for MSM supplements.

Pure Organic Ingredients

Pure Organic Ingredients, through brands like EnergyBalance and Bergstrom Nutrition, stands out as a premier producer of MSM powder, notably with the OptiMSM^® brand, which is recognized for its exceptional purity achieved through a proprietary multi-stage distillation process. This method ensures a product purity of 99.9%, significantly surpassing the purity of MSM produced via crystallization. OptiMSM^® is GRAS-designated and manufactured in a cGMP-certified, ISO-registered facility in the USA, with every batch undergoing third-party testing for optimal quality and consistency. The product contains 34% elemental sulfur, crucial for maintaining healthy tissues, and is vegan-friendly. This high-quality MSM supports joint, immune, and respiratory health.