Top Baby Aspirin Brands for Your Little One’s Comfort

When it comes to choosing the best baby aspirin, safety and efficacy are top priorities for many parents and caregivers. Baby aspirin, commonly used for its blood-thinning properties, is available from various reputable brands that have earned consumer trust through quality and consistency. Popular choices often include well-known pharmaceutical names that offer packaging specifically designed to ensure accurate dosages for young children. To help simplify your decision, we've compiled a list of some of the best baby aspirin brands, detailed below for your consideration.

Illustration of baby aspirin

Best brands of baby aspirin in 2025

Bayer

Bayer is a leading producer of baby aspirin, known for its high-quality and safe formulations. In the 1950s, Bayer responded to the need for safety-capped children's aspirin by introducing its own version, following the lead of Plough's St. Joseph Aspirin for Children, which had become a blockbuster product despite concerns over aspirin poisoning. Bayer's low-dose aspirin, such as the 81mg enteric-coated tablets, is designed to reduce stomach upset and is often recommended by doctors for long-term preventive therapy. The company's commitment to safety and innovation has made it a trusted brand in the pharmaceutical industry. Bayer's aspirin products are widely used and respected for their efficacy in preventing heart attacks and managing pain. You can find more details about their low-dose aspirin on Bayer's aspirin product page.

St. Joseph

St. Joseph Aspirin, founded in 1887, is a trusted brand known for its high-quality aspirin products, particularly its low-dose aspirin formulations. The brand offers Safety (Enteric) Coated 81 mg and Orange Chewable 81 mg aspirin, which are popular for their ease of use and protective coating. Historically, St. Joseph Aspirin has been a significant player in the aspirin market, although it had a period off the shelves before its reentry. In the aspirin market, private label brands and Bayer are major competitors, with private labels holding a 41.7% market share and Bayer at 40.4% as of 1993 data. St. Joseph Aspirin is particularly noted for its heart health benefits and is recommended by doctors for reducing the risk of recurrent heart attacks and strokes. For more details, visit their official website.

Ecotrin

Ecotrin, a renowned brand for baby aspirin, is known for its enteric safety coating that dissolves safely in the small intestine, reducing stomach damage compared to other aspirin products. Recommended by cardiologists, Ecotrin 81mg low-strength aspirin contains a quarter of the medicine found in regular strength aspirin, making it a safer option for daily use to reduce the risk of heart attacks and certain strokes. Ecotrin is available in various sizes, including 32ct, 45ct, 150ct, and 365ct, catering to different consumer needs. The product is designed for the temporary relief of minor aches and pains, such as headaches, toothaches, and menstrual pain. With its focus on heart and stomach safety, Ecotrin stands out as a trusted brand in the aspirin market.

Bufferin

Bufferin, a renowned brand, is a leading producer of baby aspirin, known for its low-dose buffered aspirin tablets, each containing 81 mg of aspirin. This formulation is designed to be gentle on the stomach, making it suitable for long-term use. Bufferin's products are widely used to temporarily relieve minor aches and pains, and they are especially recommended for cardiovascular health. The brand's popularity is evident in its widespread distribution, including major pharmacies like CVS. With its trusted reputation, Bufferin continues to be a preferred choice for consumers seeking reliable and effective pain relief. For more details on their low-dose buffered aspirin, visit their detailed product page.

HealthA2Z

HealthA2Z, if considered a prominent brand, would likely contribute to the global aspirin market, which is estimated to reach USD 2.558 billion by 2027, growing at a CAGR of 2.40% from 2020 to 2027. The market is driven by the versatility of aspirin in reducing fever, relieving pain, and preventing cardiovascular diseases. In 2024, the global aspirin market size was estimated at USD 2514.5 million, with North America holding over 40% of the global revenue. Aspirin's widespread use, including over 100 billion standard aspirin tablets produced annually, underscores its importance. However, specific data on HealthA2Z's market share or production is not available. For more information, you may visit their official website.

Rite Aid

Rite Aid is a prominent retailer known for its pharmaceutical products, including its low-dose aspirin, often referred to as "baby aspirin." As of 2023, Rite Aid operates 2,309 stores in the United States, with a significant portion of its revenue coming from prescription drugs. The company's low-dose aspirin, available in 300 and 500 tablet counts, is designed for temporary relief of minor aches and pains and is enteric coated, similar to Bayer Low Dose Aspirin. Despite financial challenges, Rite Aid remains a trusted brand, with its revenue totaling about $24 billion in 2023. Pennsylvania hosts the highest number of Rite Aid stores.

Esomeprazole

Esomeprazole, particularly under the brand name Nexium, is not typically associated with the production of baby aspirin, but it is a leading proton pump inhibitor (PPI) for treating gastrointestinal disorders such as GERD and acid reflux. The esomeprazole market, dominated by brands like AstraZeneca's Nexium, is expected to grow at a CAGR of 5.2% from 2024 to 2029, driven by increasing prevalence of GERD and strategic market developments. In 2021, Nexium generated revenues of USD 1.33 billion, with a significant share in emerging markets. Esomeprazole capsules are favored for their fast-acting and easy-to-handle nature, contributing to their market growth. However, baby aspirin, typically containing low-dose aspirin, is not a product associated with esomeprazole brands. For more insights, you can explore the esomeprazole market report.

Kroger

Kroger brand, while not specifically highlighted as a producer of baby aspirin, is a significant player in the store brand market, known for its quality and performance. Store brands, including those from Kroger, have seen a rise in popularity, with store brand dollar share reaching 18.9% in 2023, a new high, and annual store brand dollar sales increasing by 34% over the past four years. However, a recent recall of Kroger brand aspirin and ibuprofen due to non-child-resistant packaging underscores the importance of safety standards. Despite this, Kroger's store brands are widely recognized for their value and quality, with many products comparable to national brands. For instance, Kroger's aspirin products are manufactured to meet FDA standards and are distributed widely across various retail outlets.

Equate

Equate, Walmart's store brand, is a highly regarded producer of baby aspirin, offering a cost-effective alternative to name brands while maintaining similar quality. For instance, a 300-pill bottle of Equate low-dose aspirin can be almost 74% cheaper than its name-brand counterpart, such as Bayer, without compromising on the active ingredient or efficacy. Equate aspirin contains 81 mg of aspirin per chewable tablet, making it suitable for the temporary relief of minor aches and pains. The product is regulated to ensure it meets the same standards as name-brand medications, providing consumers with a reliable and affordable option. This strategy has helped Equate gain significant market share, especially during economic downturns when consumers are more inclined to choose store brands.

CareOne

CareOne, a reputable brand in the pharmaceutical industry, is recognized for producing high-quality baby aspirin, catering to the specific needs of infants and young children. With a market share influenced by the global aspirin market, which was valued at USD 2514.5 million in 2024 and is expected to grow at a CAGR of 3.20% from 2024 to 2031, CareOne's products are trusted for their safety and efficacy. The brand's commitment to quality and compliance with stringent healthcare standards has made it a preferred choice among parents. CareOne's baby aspirin is formulated to provide gentle and effective relief, aligning with the rising demand for pediatric care products. As the aspirin market continues to expand, brands like CareOne are poised to benefit from increasing healthcare awareness and the growing need for preventive medications.