Top Picks: Premium Squalane Oil Brands to Elevate Your Skincare Routine

Squalane oil has quickly become a favorite in skincare routines due to its lightweight, non-comedogenic, and highly moisturizing properties. As more people embrace this versatile oil, several brands have emerged as leaders in the market, offering high-quality products that cater to various skin types. From renowned industry giants to niche skincare specialists, each brand brings its unique formulation and dedication to purity. Curious about which brands are leading the charge in squalane oil innovation? Discover our curated list of the best options below.

Illustration of squalane oil

Best brands of squalane oil in 2025

The Ordinary

The Ordinary is renowned for its 100% Plant-Derived Squalane, a product that stands out for its high quality and sustainability. This squalane is ECOCERT approved and USDA Certified as a Bio-based Product, ensuring it meets stringent environmental and quality standards. It is a lightweight, non-comedogenic oil that provides exceptional hydration and emollience, suitable for all skin types and also beneficial for hair care by offering heat protection and reducing breakage potential. For a comprehensive review, visit this The Ordinary 100% Plant-Derived Squalane review.

Biossance

Biossance stands out as a leading producer of squalane oil, offering a sustainable, vegan, and highly effective alternative to traditional shark-derived squalane. Their sugarcane-derived squalane requires only 1 square kilometer of land to produce the world's yearly supply, saving approximately 2 million sharks annually. This innovative approach has garnered support from nine out of the top ten beauty companies, with Biossance holding over 50% of the global squalane market. Clinical studies have shown that 95% of users felt instant hydration, and 93% reported more nourished skin after two weeks of use. Biossance's commitment to sustainability and efficacy has made their squalane oil a cornerstone in the beauty industry. For more information, visit their website on Biossance's 100% Squalane Oil.

Indie Lee

Indie Lee is renowned for its high-quality squalane facial oil, which is a single-ingredient, 100% olive-derived formula that boosts moisture retention and helps diminish the appearance of fine lines. This COSMOS Natural certified oil is suitable for all skin types, including oily, dry, and sensitive skin, and is formulated without essential oils, parabens, and other harmful ingredients. It is easily absorbed into the skin, leaving no greasy residue, and can be used on the face, body, or hair. The product meets the Credo Clean Standard and is cruelty-free, gluten-free, and fragrance-free. With its affordable price point and excellent customer reviews, Indie Lee's Squalane Facial Oil is a standout in the skincare industry.

Peter Thomas Roth

Peter Thomas Roth is renowned for its high-quality squalane oil products, particularly the Oilless Oil 100% Squalane Treatment, which is derived from sustainable sugarcane and free from preservatives. This product, introduced to users as a skin-softening moisturizer, helps improve the look of fine lines, wrinkles, and skin elasticity, and it rapidly absorbs without leaving a greasy feel. It is suitable for all skin types, including sensitive and dry skin, and can also be used on cuticles, hair, and elbows for extra moisture. The product has garnered positive reviews for its effectiveness in hydrating the skin and preventing water loss. It is available at various retailers, including Amazon and Nordstrom, with prices ranging from $24 to $38.

Naturium

Naturioum stands out as a premier producer of squalane oil, offering 100% plant-derived squalane sourced from sustainably harvested sugarcane. This bio-based squalane is produced through biofermentation using non-pathogenic yeast, ensuring high purity and stability with minimal impurities. Unlike historical sources from shark liver oil, Naturium's method is environmentally friendly and safe. The squalane from Naturium helps replenish the skin's natural moisture barrier, which naturally declines after the age of 30, and it is rich in antioxidant and anti-inflammatory properties. This makes it an excellent choice for maintaining healthy, hydrated skin.

Good Molecules

Good Molecules is a highly regarded brand for its 100% plant-derived squalane oil, which is cruelty-free, vegan, and fragrance-free, making it suitable for all skin types. Launched by Beautylish in 2022, Good Molecules offers a budget-friendly alternative to premium skincare brands, with its squalane oil providing intense hydration and replenishing fatty acids and antioxidants. The oil is non-comedogenic and fast-absorbing, ideal for daily use. Despite being slightly more expensive than The Ordinary's option, Good Molecules' squalane oil is praised for its effectiveness and eco-friendly packaging. It is available in a 13 ml / 0.44 oz size. You can find more information about their squalane oil on their official product page.

Timeless Skin Care

Timeless Skin Care is renowned for its 100% Pure Squalane Oil, derived from olives, which provides exceptional moisturizing and protective benefits for all skin types, including oily, dry, combination, and sensitive skin. This lightweight, non-comedogenic oil helps minimize moisture loss, regulates oil production, and instantly relieves tight and dry skin. In a 4-week study involving 25 participants, 100% agreed that their skin felt instantly hydrated and nourished. Squalane Oil from Timeless Skin Care is also anti-bacterial and ideal for acne-prone skin, making it a versatile and effective skincare staple. It is cruelty-free, vegan, and free from parabens, sulfates, fragrance, and dyes.

Youth to the People

Youth to the People is renowned for its high-quality squalane oil products, leveraging the ingredient's exceptional moisturizing and skin-protective properties. Squalane, derived from olive oil, is a key component in their formulations, offering stability and compatibility with all skin types. The brand's Superberry Hydrate + Glow Dream Mask, for example, incorporates squalane to provide deep hydration and antioxidant protection. With a focus on sustainability, Youth to the People prefers plant-based sources of squalane, aligning with consumer preferences and environmental concerns. This approach has contributed to the brand's growth and popularity, particularly among those seeking effective and eco-friendly skincare solutions.

Ole Henriksen

Ole Henriksen is renowned for its high-quality skincare products, particularly its formulations that incorporate squalane oil, a potent moisturizer. The HydraBarrier Nourishing Face Oil, for example, contains squalane along with other nourishing ingredients like Scandinavian berry oils and ceramides, which help in hydrating the skin and restoring its natural bounce. This face oil has been clinically proven to strengthen the moisture barrier by 19% and reduce fine lines and wrinkles by 34% in just one day. The brand's commitment to using naturally derived ingredients and its focus on delivering visible results have made it a favorite among skincare enthusiasts. With its luxurious and effective products, Ole Henriksen continues to set standards in the skincare industry.

Sephora Collection

Sephora Collection is renowned for its high-quality squalane oil products, leveraging 100% plant-derived squalane sourced from sugar cane, which is ECOCERT approved and USDA Certified Bio-based. This formulation enhances surface-level hydration, is non-comedogenic, and suitable for all skin types. The market for squalane oil is projected to grow at a CAGR of around 7% until 2028, driven by increasing consumer preference for natural and sustainable ingredients. Sephora's product offerings align with this trend, catering to the rising demand for clean and organic beauty products. The global squalane market, valued at USD 141 million in 2022, is expected to reach USD 202 million by 2028.