Top Hyaluronic Acid Injection Brands to Elevate Your Skincare Game

Hyaluronic acid injections have become increasingly popular as a go-to solution for achieving youthful, rejuvenated skin. With numerous brands available on the market, choosing the ideal one can be a nuanced task, especially when considering factors such as purity, longevity, and efficacy. Top brands have distinguished themselves by providing exceptional quality and proven outcomes, making them favorites among dermatologists and patients alike. Interested in discovering the leading names for hyaluronic acid injections and what sets each apart? Explore the detailed analysis below.

Illustration of hyaluronic acid injections

Best brands of hyaluronic acid injections in 2025

Juvéderm

Juvederm, a leading brand in the hyaluronic acid dermal filler market, is renowned for its long-lasting and natural-looking results. It is the #1 chosen dermal filler collection in the US, with over 90% of filler patients opting for hyaluronic acid-based fillers. Juvederm products, such as Juvederm Ultra, Ultra Plus, Volbella, Vollure, and Volux, are designed to address various signs of aging, including fine lines, wrinkles, and facial volume loss. The brand's unique Hylacross technology ensures smoother and more durable results. In 2022, Allergan (AbbVie), the company behind Juvederm, held a significant market share along with other major players like Galderma and Merz Pharma.

Restylane

Restylane, a leading brand in the hyaluronic acid injections market, is renowned for its high-quality and durable fillers. In 2023, hyaluronic acid fillers, including those from Restylane, captured 25.90% of the dermal filler market share due to their safety, biocompatibility, and durability. Restylane fillers, such as Restylane Lyft and Restylane Silk, utilize proprietary technologies like NASHA and XpresHAn/Optimal Balance Technology, which enhance their longevity, with some lasting between 9-12 months. The brand's products are widely used for various applications, including wrinkle removal, lip augmentation, and restoring facial volume. Restylane's advanced formulations and extended durability have made it a popular choice among practitioners and patients alike.

Belotero

Belotero, a renowned brand from Merz Aesthetics, stands out as a leading producer of hyaluronic acid injections, known for its high cohesivity and water-binding capacity. The Belotero Balance (+) filler has demonstrated significant efficacy, showing a greater reduction in nasolabial folds compared to bovine collagen at weeks 8, 12, and 24, with results lasting 6 months or longer for a majority of patients. In clinical trials, Belotero Balance (+) was found to be the most cohesive among FDA-approved HA fillers, with 89.6% of subjects opting for retreatment during the open-label extension phase. The hyaluronic acid segment, which includes Belotero products, dominated the dermal filler market in 2023, capturing 25.90% of the market share due to its safety, biocompatibility, and durability. The global dermal filler market, led by hyaluronic acid-based fillers like Belotero, is projected to grow at a CAGR of 8.2% to reach USD 10.26 billion by 2032.

Teosyal

Teosyal is a leading brand in the dermal filler market, particularly renowned for its hyaluronic acid injections, which dominated the market with a 25.90% share in 2023 due to their safety, biocompatibility, and durability. Teosyal's RHA Dynamic Fillers, such as Teosyal RHA 1, 2, 3, and 4, are designed to address various facial concerns, including fine lines, medium-depth wrinkles, and deeper nasolabial folds, with results lasting longer due to their resilient properties. Clinical studies have shown that Teosyal Deep Lines(r) has an average effective clinical duration of 10.5 months with no reported adverse reactions. The brand's products are widely used and valued, with 90% of patients finding dermal filler procedures valuable according to RealSelf statistics. Teosyal continues to innovate, with recent clinical trials and product launches further solidifying its position in the aesthetic treatments market. For more information on their range of Teosyal RHA Dynamic Fillers, please visit their website.

Revanesse

Revanesse, a brand by Prollenium Medical Technologies Inc., stands out as a leading producer of hyaluronic acid injections, known for its FDA-approved dermal fillers that provide natural-looking and long-lasting results. With a success rate of 78.4% in wrinkle improvement and a 44.4% score of "much improved or very much improved" on the Patient Global Aesthetic Improvement scale, Revanesse products are highly regarded. These injectables, such as Revanesse Versa+ and Revanesse Lips+, are designed to smooth, plump, and contour facial features, offering minimal recovery time and reduced discomfort. User reviews on RealSelf highlight the effectiveness of Revanesse treatments, with an average rating of 63%. The brand's advanced cross-linking technology ensures durable and smooth consistency, making it a compelling choice for those seeking minimally invasive aesthetic treatments.

Stylage

Stylage, developed by Laboratoires Vivacy, is a leading brand in the hyaluronic acid market, known for its innovative formulations that combine cross-linked hyaluronic acid with natural antioxidants like mannitol. This unique blend enhances filler longevity, with effects lasting 6 to 18 months, and reduces post-injection inflammation. Stylage fillers are versatile, suitable for various applications including lip correction, volume restoration, and skin rejuvenation, and have been validated by clinical studies such as the 18-month Beauty Volume study. The inclusion of antioxidants like mannitol slows down the degradation of hyaluronic acid, ensuring more prolonged effects. With a high concentration of hyaluronic acid, ranging from 16 mg/g to 26 mg/g, Stylage offers natural-looking enhancements and high patient satisfaction.

Profhilo

Profhilo is a leading brand in the field of hyaluronic acid injections, renowned for its revolutionary skin booster treatment that has been transforming the anti-aging landscape since its inception in 2015. Utilizing NAHYCO technology, Profhilo contains a high concentration of hyaluronic acid (64mg/2ml), comprising both high and low molecular weight HA, which effectively stimulates collagen, elastin, and adipocytes to remodel sagging skin tissue. This treatment involves just five injection points per side of the face, ensuring even hydration and bio-stimulation. Profhilo is highly biocompatible, produced through bio-fermentation, and has shown significant efficacy in clinical studies, with subjects experiencing clear improvements in skin roughness and laxity. Recommended treatments include two sessions a month apart, with follow-up treatments every six months for optimal results.

Perfectha

Perfectha is a renowned brand in the aesthetic medicine sector, known for its advanced line of hyaluronic acid (HA) gel fillers that effectively address wrinkles, hydrate the skin, and add volume. Developed by French scientists, Perfectha fillers offer excellent results in volume restoration, wrinkle correction, and facial contouring, with a high cross-linking rate of 90% that ensures longer-lasting effects. These fillers, produced by Laboratoire ObvieLine, are made from non-animal hyaluronic acid and are approved by regulatory bodies such as the FDA and MHRA. The efficacy of Perfectha fillers is evident, with improvements maintained in 76% and 57% of patients for nasolabial folds, and 72% and 45% for lips after three and six months, respectively.

Neauvia

Neauvia is a leading brand in the hyaluronic acid market, renowned for its advanced formulations and innovative PEGDE crosslinking technology, which ensures high durability and biocompatibility. Their fillers, such as NEAUVIA Intense, have shown significant efficacy in correcting moderate-to-severe nasolabial folds, with 96.6% of patients experiencing an improvement immediately after treatment. Neauvia fillers provide deep hydration, restore facial volume, and reduce wrinkles, offering results that last six to nine months. The brand's products are designed for various treatment areas, including the face, lips, neck, and intimate areas. With a high safety profile and patient satisfaction, Neauvia stands out as a favored option in the dermal filler market. For more insights and reviews, visit Neauvia reviews.

Yvoire

Yvoire is a renowned brand in the hyaluronic acid market, known for its high-quality dermal fillers. Studies have shown that Yvoire's products, such as YVOIRE(r) classic s and YVOIRE(r) volume s, exhibit complete clinical biodegradation in 93.5% and 98.5% of recipients, respectively, within 12 months of injection. These fillers are effective in correcting nasolabial folds and maintaining volumetric effects, with biphasic fillers like Yvoire Contour retaining over 50% of the injected volume after 2 years. The safety profile of Yvoire's products is also impressive, with most treatment-related adverse events being mild and local injection-site reactions. This makes Yvoire a trusted choice in the aesthetic and dermatological fields. For more detailed clinical insights, please refer to the study published in the Journal of Cosmetic Dermatology.