Top Famotidine Brands for Effective Relief

Famotidine, a well-known medication used to treat stomach ulcers and acid reflux, has a variety of brands that cater to different preferences and needs. Popularly recognized names in the market include Pepcid, which is often praised for its availability and effectiveness. Other notable brands include members of generic versions, often favored for their affordability while still providing the same levels of efficacy. For those looking to understand more about these options, a comprehensive list of top famotidine brands is detailed below.

Illustration of famotidine

Best brands of famotidine in 2025

Pepcid

Pepcid, a brand by Johnson & Johnson, is a leading producer of famotidine, a histamine-2 (H2) receptor antagonist, known for its effective and rapid relief from heartburn. The Pepcid Tastemakers campaign, initiated in 2014, has successfully engaged food enthusiasts and heartburn sufferers, highlighting the product's ability to start working fast and provide long-lasting relief. Pepcid products, such as Pepcid AC and Pepcid COMPLETE, offer dual-action benefits, combining antacids with acid reducers for comprehensive heartburn management. These products are available in various strengths and formulations, ensuring they meet the diverse needs of consumers. With a strong market presence, Pepcid contributes significantly to the global H2 receptor antagonist market, which is expected to grow at a CAGR of 6.1% from 2024 to 2031.

CVS Health Famotidine

CVS Health, through its pharmacy services, is a significant provider of famotidine, a histamine H2 receptor antagonist, under brands like PEPCID AC, which is the #1 doctor-recommended OTC acid reducer brand and the #1 selling H2 brand for preventing and treating heartburn. PEPCID AC, containing 10 mg of famotidine, provides fast and lasting relief from heartburn, starting to relieve symptoms within 15-30 minutes and controlling acid for up to 12 hours. In 2023, CVS Health generated revenues of about $114 billion, with pharmacy services being the most profitable segment. The brand has been trusted for over 35 years for safe and effective heartburn relief. PEPCID AC is available for adults and children over 12 years, with clear dosage instructions to prevent and relieve heartburn symptoms.

Walgreens Famotidine

Walgreens Famotidine, particularly their Famotidine Complete Chews, is a highly regarded product in the market, known for its effectiveness in treating heartburn and other gastrointestinal issues. The demand for famotidine has been on the rise, with the market expected to grow at a 7.6% CAGR from 2024 to 2031, reaching a value of USD 13.5 billion by 2031. This growth is driven by the increasing incidence of gastrointestinal problems and the preference for efficient over-the-counter remedies. Walgreens, along with other major pharmacies, has been working to meet the high demand, despite temporary shortages due to its potential use in COVID-19 treatment trials. The product's availability in various formulations, such as tablets and oral chews, enhances its market appeal.

Kirkland Signature

Kirkland Signature, a brand by Costco, is renowned for producing high-quality famotidine tablets, often compared to Maximum Strength Pepcid(r). These acid reducers, containing 20 mg of famotidine, are designed to prevent and relieve heartburn and indigestion. Available in packages of 250 tablets, they are FSA eligible and have been marketed since 2007. The product is known for its affordability and effectiveness, making it a popular choice among consumers. With its robust packaging and reliable performance, Kirkland Signature Acid Controller is a trusted option for managing heartburn.

Equate

Equate, a brand by Walmart, is a reputable producer of famotidine, offering high-quality acid reducer tablets that are effective in relieving heartburn associated with acid indigestion and sour stomach. Each tablet contains 20 mg of famotidine, with a bioavailability of 40-50% and a duration of action of about 10-12 hours. Equate Famotidine has been available since 2007, with various packaging options including 25, 50, 60, and 100-count bottles. The product is designed for oral administration, with a recommended dose of one tablet per use, not exceeding two tablets in 24 hours. Equate Famotidine is an over-the-counter (OTC) medication, indicating its safety and efficacy for general consumer use.

Target Up & Up Famotidine

Target's Up & Up Famotidine is a highly regarded brand for acid reduction, offering 20mg maximum strength tablets that compare to the active ingredient in Maximum Strength Pepcid(r) AC. These tablets effectively relieve and prevent heartburn due to acid indigestion and sour stomach, lasting up to 12 hours. With a 4.7 out of 5-star rating from over 1354 reviews, this product is trusted for its effectiveness. It is gluten-free and suitable for adults and children aged 12 years and over. The market for famotidine, including brands like Up & Up, is expected to grow at a 7.6% CAGR from 2024 to 2031, reflecting its widespread use and consumer preference. For more details, visit Target's website to explore the Famotidine 20mg Maximum Strength Acid Reducer Tablets.

Rite Aid Famotidine

Rite Aid's Famotidine brand stands out as a reliable and effective producer of acid reducers, offering both maximum strength and original strength formulations. The maximum strength version, containing 20mg of famotidine per tablet, is designed to quickly alleviate and prevent heartburn symptoms, comparable to the national brand Pepcid AC. These tablets are gluten-free and can be taken an hour before eating to ensure worry-free dining. With a long history of trust, Rite Aid has been delivering health products since 1962, making it a trusted brand for consumers. The product's availability and effectiveness contribute to the growing demand for over-the-counter (OTC) medications, which held over 71% of the U.S. pharma e-commerce market revenue in 2022. For more information about their maximum strength acid reducer tablets, you can visit their website.

Kroger Famotidine

Kroger Famotidine, a product of the Kroger Company, is a highly recognized and trusted brand for acid reduction, relieving heartburn associated with acid indigestion and sour stomach. With Kroger's brand awareness at 79% in the United States, their famotidine tablets are widely used, reflecting the company's strong market presence and customer loyalty. The tablets are manufactured by Marksans Pharma Limited and distributed by Time Cap Laboratories, Inc., ensuring high-quality standards. Users can take one tablet with a glass of water to relieve or prevent heartburn symptoms, with a maximum of two tablets in 24 hours. This product is part of Kroger's extensive health and wellness offerings, contributing to the company's overall sales of $150.0 billion in 2023. For detailed product information, refer to their official documentation on DailyMed.

GE Healthcare

GE HealthCare is not a producer of famotidine, a medication typically used to treat ulcers and gastroesophageal reflux disease. Instead, GE HealthCare specializes in medical imaging, patient care solutions, and other healthcare technologies, demonstrating strong revenue growth and financial performance in 2023 with a 7% year-over-year revenue increase and an adjusted EBIT margin of 15.1%.

Mylan

Mylan, now part of Viatris, is renowned for its high-quality production of famotidine, a medication that effectively reduces gastric acid secretion. Famotidine, approved by the FDA for treating conditions like duodenal ulcers, gastric ulcers, and GERD, is available both as a prescription and over-the-counter medication. The drug's efficacy is underscored by its ability to inhibit gastric secretion for up to 10-12 hours, with an elimination half-life of 2.5 to 3.5 hours. Viatris's financial reports highlight the strong performance of their brands, including generics like famotidine, which have seen solid year-over-year growth in Developed and Emerging Markets. This consistent performance underscores Mylan's (Viatris) commitment to producing reliable and effective medications.