Top Early Pregnancy Test Brands: Clearblue, First Response, and EPT

Embarking on the journey of parenthood is an exciting time, and for many, knowing early can make all the difference. An accurate early pregnancy detection test provides that crucial information with clarity and confidence. In this article, we've compiled a list of the best brands renowned for their reliability and sensitivity, catering to those eager to confirm pregnancy at the earliest stage. Discover your options below and find the perfect early detection brand for your needs.

Illustration of early pregnancy detection

Best brands of early pregnancy detection in 2025

First Response

First Response is a leading brand in early pregnancy detection, renowned for its high accuracy and sensitivity. The First Response Early Result Pregnancy Test can detect pregnancy up to 6 days before a missed period, with a detection rate of 62% at 6 days early and increasing to over 99% by the day of the missed period. In laboratory testing, this test detected pregnancy hormone levels in 68% of cycles 5 days before the expected menstrual period and 100% of cycles 3 days before. It is also notable for its ability to detect scant amounts of the human chorionic gonadotropin (hCG) hormone, making it a reliable choice for early pregnancy testing. This test has been praised for its accuracy, with studies showing it detects 97% of pregnancies on the day of missed menstrual bleeding.

Clearblue

Clearblue is a leading brand in early pregnancy detection, renowned for its high accuracy and innovative features. Their Digital Ultra Early Pregnancy Test can detect pregnancy up to six days before a missed period, with a sensitivity of 10mIU/ml and an accuracy of over 99% from the day of the expected period. In lab testing, this test detected pregnancy in 78% of women six days before their missed period and in over 99% of women from three days before. For more details on the benefits of Clearblue Digital Pregnancy Tests, visit their official website.

EPT

The EPT (Error Proof Test) brand is renowned for its reliability and accuracy in early pregnancy detection, with tests that can detect pregnancy as early as five days before a missed period. Used correctly, EPT tests are up to 99% accurate for positive results and 80% accurate for negative results, making them a trusted choice since their introduction. The EPT digital tests are particularly notable, detecting 67% of pregnancies even before the missed period, and providing clear "+"/"Pregnant" or "-"/"Not Pregnant" readings. This advanced hormone detection technology ensures quick and precise results, typically within three minutes. For early testing, EPT tests are highly recommended due to their ease of use and high accuracy. Discover more about EPT pregnancy tests.

Accu-Clear

The Accu-Clear brand is renowned for its reliable and accurate early pregnancy detection tests, offering results as early as 5 days before the missed period with a detection rate of 53% during this period. These tests are over 99% accurate at detecting typical pregnancy hormone levels from the day of the expected period. The Accu-Clear 2-Minute Pregnancy Test provides clear plus (+) and minus (-) results in just two minutes, making it a user-friendly and swift solution. This test is designed to detect the presence of hCG in urine, ensuring high accuracy and peace of mind for users. With its sensitive detection technology, Accu-Clear stands out as a trusted name in pregnancy testing.

Pregmate

Pregmate is a highly regarded brand for early pregnancy detection, offering accurate and reliable pregnancy tests that can be used as early as 5 days before a missed period, with results over 99.8% accurate. These tests detect the pregnancy hormone hCG at a sensitivity level of 25 miu/ml, making them effective for early pregnancy testing. The tests are also affordable, priced as low as 19¢ per test, and are known for their clear and easy-to-read results. Pregmate's products are designed to maximize the chances of accurate detection, with a recommended testing time on the day the next period is supposed to begin for a 99% accurate result. This makes Pregmate a trusted choice for couples trying to conceive.

ClinicalGuard

ClinicalGuard is renowned as one of the best producers for early pregnancy detection, offering highly accurate and affordable pregnancy test strips. These tests boast a 4.4-star rating from Amazon reviewers, praised for their accuracy and quick results. ClinicalGuard Pregnancy Test Strips can detect hCG levels with a high degree of sensitivity, making them a reliable choice for those trying to conceive. With a pack of 50 strips available for under $15, they are an economical option for frequent testing. The tests are easy to use and provide reliable results, with few reports of faulty tests.

Easy@Home

The Easy@Home Pregnancy Test Midstream is one of the best options for early pregnancy detection, boasting an accuracy of over 99.8% when used properly, and complying with the FDA recommended cut-off level of 25 mIU/ml hCG. This test can detect pregnancy as early as before a missed period, with results appearing within 5 minutes. It is designed for comfort and ease of use, with a user-friendly design and dedicated customer support. False positives are rare but can occur due to certain health conditions or medications, while false negatives may happen if hCG levels are not yet high enough. For accurate results, it is advised to test again after 2-3 days if the initial test line is faint.

Wondfo

Wondfo is renowned as one of the best producers for early pregnancy detection, offering highly sensitive pregnancy tests that can detect human chorionic gonadotropin (hCG) as early as 7 days after conception, with a detection limit of 10 mIU/mL, which is more accurate than many other commercial tests that typically have a limit of 25 mIU/mL. Their tests achieve a high pregnancy detection rate, with up to 98% accuracy just two days before the expected menstrual period. Clinical studies have shown that Wondfo's tests have an agreement rate of 99.5% with other predicate devices. The tests are also user-friendly, with a Flesch-Kincaid reading grade level of 7, indicating ease of use and understanding. Wondfo's products are certified with CE, CLIA WAIVED, and NMPA qualifications, ensuring reliability and compliance with international standards.

Natalist

Natalist is a leading brand in early pregnancy detection, offering tests that are clinically proven to be over 99% accurate when used on the day of the expected period. These tests can detect human Chorionic Gonadotropin (hCG) up to 5 days before the expected period, with accuracy rates of 77% at five days, 97% at four days, and over 99% at three days before the period. Natalist tests are FDA Cleared and have been evaluated in clinical studies involving over 1,000 urine samples. They are also 100% plastic neutral, using 81% less plastic than midstream tests. The tests are easy to use and provide results within 5 minutes. For more information, visit their early pregnancy test strips page.

Rite-Aid

The Rite Aid Early Result Pregnancy Test is a highly reliable and user-friendly option for early pregnancy detection, boasting over 99% accuracy from the day of the expected period. This test is simple to use, requiring only one step where the absorbent tip is held in the urine stream for 10 seconds, with results available in just 5 minutes. It is comparable to the well-regarded First Response brand and is eligible for FSA and HSA reimbursement. Manufactured in China, this product is part of Rite Aid's pharmacy brand, known for its quality and affordability. In the market, Rite Aid competes with major brands, though First Response held a 27.1% market share in 2019. For more details about their product, visit the Rite Aid Early Result Pregnancy Test page.