Top Urea Cream Brands: A Smoother Skin Solution

As the search for effective skincare solutions intensifies, urea cream has emerged as a popular choice for those dealing with dry or rough skin conditions. Known for its ability to effectively hydrate and exfoliate, urea cream provides relief to many who suffer from conditions like eczema and psoriasis. Several brands have carved out their reputation in the market with their top-quality creams that have been praised by both dermatologists and users alike. Curious to discover which brands top the list for urea cream products? Read on below.

Illustration of urea cream

Best brands of urea cream in 2025

CeraVe

CeraVe is renowned as one of the best producers of urea creams, with a brand awareness of 76% among face care users in the United States and a usage share of 29%. Their products, such as the Diabetics' Dry Skin Relief Moisturizing Cream and Intensive Moisturizing Lotion, feature urea and other essential ingredients like ceramides and hyaluronic acid to provide long-lasting hydration, with the Intensive Moisturizing Lotion offering up to 72-hour hydration and a 42% increase in skin's moisture barrier function.

Eucerin

Eucerin is renowned as one of the best producers of urea cream, with a brand awareness of 80% among face care users in Germany and a usage share of 16% in the same market. The Eucerin UreaRepair range, which includes products like the UreaRepair PLUS 30% Urea Cream, is clinically and dermatologically proven to provide intensive moisturization and improve skin conditions such as Keratosis Pilaris and Psoriasis. This cream contains a unique combination of highly-concentrated urea, ceramides, and Natural Moisturizing Factors (NMFs) to hydrate and repair the skin's barrier. Around 12% of face care users in Germany express loyalty to the brand, indicating a strong customer base. The brand's strong performance is also reflected in its sales growth, particularly in regions like North America and Latin America, where Eucerin achieved significant organic sales growth in 2022.

UreaRepair Plus

Eucerin's UreaRepair Plus brand is renowned for its highly effective urea creams, particularly the 30% Urea Cream, which provides intense hydration for up to 48 hours, instantly relieves itchy and irritated skin, and promotes wound healing. This cream, suitable for extremely dry and rough skin areas like elbows, knees, hands, and feet, also contains ceramides to strengthen the skin barrier and prevent moisture loss. Clinical and dermatological tests have shown that the skin becomes visibly smoother and suppler within just one week of use. The product is fragrance-free, easily absorbed, and dermatologically tested, making it a safe and effective choice. It is also recommended for conditions such as Keratosis Pilaris and psoriasis.

PurSources

PurSources is renowned for its high-quality urea creams, particularly the PurSources Urea 40% Cream, which is formulated to effectively remove thick, callused areas and repair cracked heels by hydrating and softening dry skin. This 40% urea concentration makes it highly effective for treating dry skin conditions, such as eczema and psoriasis. The cream also includes a free pumice stone to enhance its callus-removing capabilities. With its strong moisturizing properties, it helps in rehydrating and soothing rough, dead, and dry skin. This product is a popular choice for its ability to revitalize the skin and promote a healthy appearance.

AmLactin

AmLactin is the #1 Dermatologist Recommended Moisturizer Brand with Lactic Acid, offering a range of products with concentrations of 5-15% lactic acid. Their formulas are designed for various skin care needs, including everyday exfoliants, advanced body care, and targeted treatments. Products like the Ultra Smoothing Cream and Intensive Healing Lotion feature 15% lactic acid, while the Daily Nourish Lotion comes in 5% and 12% concentrations. AmLactin has been recognized for its effectiveness, winning Allure Best of Beauty awards. As of 2023, it remains a top choice among dermatologists. For more information on their full product line, visit the AmLactin website.

Flexitol

Flexitol is renowned as one of the best producers of urea cream, particularly with its 10% Urea Cream, which is designed for the relief of rough, dry, and anhidrotic skin conditions. This cream is applied one to three times daily and is suitable for adults and children over one year. It contains a high concentration of urea, along with other ingredients like wool fat, light liquid paraffin, and shea butter, to provide effective moisturization and hydration. The product is available in various package sizes, including 150g and 500g, with NHS indicative prices of £5.25 and £12.36 respectively, as of December 2023. Flexitol's urea cream is also recommended for conditions such as keratosis pilaris and diabetic foot care.

Neoteric Cosmetics

Neoteric Cosmetics is renowned for its high-quality urea creams, particularly the Neoteric Diabetic Skin Care Advanced Healing Cream, which features a formulation designed to speed healing, improve circulation, and protect the skin. This cream, available since its patented treatment was developed, includes ingredients like Dimethicone as a skin protectant and other components such as Aloe Barbadensis Juice and Tocopheryl Acetate (Vitamin E) to enhance its therapeutic benefits. The product is intended for external use only and is advised against use on deep or puncture wounds, animal bites, or serious burns. With its comprehensive ingredient list, including water, peroxidized corn oil, and mineral oil, Neoteric Diabetic Skin Care Advanced Healing Cream is a trusted choice for skin care. The cream's effectiveness and safety have been well-documented, making Neoteric Cosmetics a reliable brand in the skincare industry.

Isdin

Isdin is renowned as one of the best producers of urea creams, particularly with their Ureadin range, which is designed to intensely hydrate and repair dry, rough, and dehydrated skin. The Ureadin intense hydration cream, for instance, contains 5% urea, omega-6, and ceramides to restore the skin's hydrolipidic layer and provide SPF 20 protection. In clinical trials, ISDIN's 10% urea lotion has shown significant improvement in skin dryness and pruritus in hemodialysis patients, with an 82% reduction in skin roughness after four weeks. The Ureadin Ultra 20 Anti-Roughness Cream features 20% urea for deep hydration and gentle exfoliation, making it ideal for very dry skin. These products highlight Isdin's commitment to developing effective moisturizing solutions.

TheraTree

TheraTree is renowned as one of the best producers of urea cream, leveraging its emollient, moisturizing, and keratolytic properties to enhance skin barrier function. Their urea creams, available in concentrations such as 10% to 40%, are highly effective in treating conditions like psoriasis, xerosis, and eczema. With a strong focus on dermatological applications, TheraTree's products are often combined with other active ingredients like bifonazole, hydrocortisone, and salicylic acid to provide comprehensive skin care solutions. The company's commitment to quality and efficacy has made their urea creams a preferred choice among dermatologists and patients alike. As the global urea market continues to grow, with projections reaching USD 99.3 billion by 2033, TheraTree remains a significant player in the dermatological segment.

Revitaderm

Revitaderm, a brand by Blaine Labs, is renowned for its high-quality urea creams, particularly the Revitaderm 40, which contains 40% urea and is effective in treating hyperkeratotic lesions and exfoliative keratolysis. This thick white gel-cream also includes aloe vera gel, tea tree oil, and chamomile, making it a soothing and effective treatment. Introduced around 2015, it has been praised for its ability to reduce peeling and promote healing. The product is available in 4 oz and 8 oz jars and is made in the U.S. Despite some products being discontinued, Revitaderm's formulations remain highly recommended for skin care. For further information about Revitaderm 40 and its usage, you can read more on the Never Say Die Beauty blog.