Top NAC Supplement Brands You Need to Know

The popularity of N-Acetyl Cysteine (NAC) supplements has risen significantly due to their potential health benefits, particularly regarding antioxidant support and liver health. As more consumers turn their attention to natural supplements for overall wellness, choosing the right brand becomes crucial to ensuring both quality and efficacy. Some brands have set themselves apart by ensuring high-quality sourcing, rigorous testing, and transparency with their product formulations. For a comprehensive look at some of the best NAC supplement brands available on the market, explore our detailed list and insights below.

Illustration of nac supplement

Best brands of nac supplement in 2025

Thorne Research

Thorne Research is a leading brand in the production of N-Acetyl-L-Cysteine (NAC) supplements, known for its high-quality and effective products. The global NAC supplements market, which includes Thorne Research, was estimated at USD 616.7 million in 2023 and is expected to grow at a CAGR of 8.2% from 2024 to 2030. Thorne Research NAC supplements support whole-body health by maintaining optimal glutathione levels, fighting oxidative stress, and promoting healthy lung, respiratory, and liver function. The market dominance of NAC supplements in North America, where Thorne Research operates, accounts for over 42.1% of the global revenue share. Thorne Research's commitment to quality and efficacy aligns with the stringent safety and efficacy requirements of the regulatory framework in North America.

Jarrow Formulas

Jarrow Formulas is a renowned brand in the health supplement industry, particularly noted for its high-quality N-Acetyl-L-Cysteine (NAC) supplements. Founded in 1977, Jarrow Formulas has built a reputation over nearly 50 years by focusing on innovative scientific research and funding studies on their products. Their NAC supplements, such as the NAC Sustain, are formulated to provide superior antioxidant support, promote glutathione production, and aid in liver detoxification. The company's commitment to quality is evident in their adherence to Current Good Manufacturing Practices (cGMP) and their accumulation of 37 awards for their innovative supplements. Jarrow Formulas' products are crafted to support optimal health, making them a trusted choice for consumers.

NOW Foods

NOW Foods is a renowned brand in the supplement industry, particularly for its N-Acetyl Cysteine (NAC) products, which are valued for their high quality and effectiveness in replenishing glutathione and supporting immune health. As a family-owned company since 1968, NOW Foods ensures its NAC supplements are non-GMO, kosher, and halal, with products like the 600 mg NAC capsules being frequently purchased for their antioxidant properties and detoxification benefits. The global NAC supplements market, in which NOW Foods is a key player, is expected to grow at a CAGR of 8.2% from 2024 to 2030, with North America holding over 42.1% of the market share. NOW Foods' commitment to GMP quality assurance and stringent safety standards enhances consumer confidence. Their NAC supplements are also vegan and vegetarian friendly, making them a popular choice for a wide range of consumers.

Life Extension

Life Extension is a highly regarded brand for N-Acetyl-L-Cysteine (NAC) supplements, known for its high-quality and effective products. Their NAC supplement contains 600mg of the nutrient per capsule, which is easily absorbed and supports immune, bronchial, respiratory, and liver health. Life Extension's NAC also helps replenish the body's supply of glutathione, a powerful antioxidant. The brand offers a generous money-back guarantee of up to one year and provides certificates of analysis to ensure product quality and purity. With a strong presence in the market, Life Extension captured a significant share of the NAC supplements market, particularly in North America, which held over 42.1% of the market share in 2023. Find more details about their N-Acetyl-L-Cysteine supplement by Life Extension.

Pure Encapsulations

Pure Encapsulations is renowned as one of the best producers of NAC (N-Acetyl-L-Cysteine) supplements, offering high-quality, hypoallergenic, and vegan-friendly products. Their NAC supplements are formulated to promote healthy lung tissue and respiratory function, support cellular antioxidant defense, and enhance glutathione levels, with studies showing significant improvements in upper respiratory tract and immune system health over six months in 262 participants. The supplements are free from unnecessary additives and common allergens, ensuring purity and effectiveness. Additionally, a combination of NAC and glycine has been shown to increase red blood cell glutathione levels by up to 53% in some studies. Pure Encapsulations' products are backed by verifiable science and are recommended for individuals aged 18 and above.

Solgar

Solgar, a renowned brand under Nestle Health Science, stands out as a leading producer of N-Acetyl Cysteine (NAC) supplements, particularly through its Solgar Cellular Nutrition line. This line features a patented blend of Glycine and NAC, known as GlyNAC, which is clinically proven to reduce oxidative stress and support cellular health, as evidenced by a 2023 RCT. The global NAC supplements market, in which Solgar is a key player, is expected to grow at a CAGR of 8.2% from 2024 to 2030, reaching USD 1.07 billion by 2030. Solgar's products are designed to work in sync with the body's natural cellular processes, enhancing immune function and overall well-being. With a strong presence in North America, which holds over 42.1% of the NAC market share, Solgar continues to innovate and provide high-quality supplements.

Doctor's Best

Doctor's Best is a renowned brand in the N-Acetyl-L-Cysteine (NAC) supplement market, known for its high-quality products that boost glutathione production, support liver health, and enhance detoxification processes. The brand's NAC Detox Regulators, which include NAC, selenium, and molybdenum, are highly valued for their antioxidant properties and role in supporting immune health and respiratory function. In 2023, the global NAC supplements market, where Doctor's Best is a key player, accounted for a revenue share of 62.3% in dietary consumption, with North America capturing over 42.1% of the market share due to its robust healthcare infrastructure. Doctor's Best NAC supplements are gluten-free, non-GMO, and vegetarian, making them a popular choice among health-conscious consumers. The brand's products are also recognized for their effectiveness in managing anxiety and improving overall well-being.

Source Naturals

Source Naturals is a reputable brand in the N-Acetyl-L-Cysteine (NAC) supplement market, known for its high-quality products. Their NAC supplements, such as the 1,000 mg 120 Tabs, are formulated to support immune health, detoxification, and respiratory function, leveraging NAC's role as a precursor to glutathione. The market for NAC supplements has seen significant growth, with a 61% increase in sales in 2021 compared to 2020, and the tablets and capsules segment, which Source Naturals is part of, accounted for 59.9% of the market share in 2023. The global NAC supplements market is expected to grow at a CAGR of 8.2% from 2024 to 2030. Source Naturals' products are hypoallergenic, containing no yeast, dairy, egg, gluten, corn, soy, or wheat, making them a preferred choice for consumers with dietary restrictions.

Nutricost

Nutricost is a highly regarded brand in the N-Acetyl-L-Cysteine (NAC) supplement market, known for its high-quality, vegetarian-friendly, Non-GMO, Gluten-Free, and Soy Free NAC capsules. Each serving of Nutricost NAC contains 600 mg of potent NAC, making it a popular choice for supporting immune health, detoxification, and respiratory function. The brand's products are favored for their bioavailability and efficacy, contributing to the significant market share of NAC supplements, with the global market expected to grow at a CAGR of 8.2% from 2024 to 2030. Nutricost's commitment to quality and consumer preferences aligns with the increasing demand for dietary supplements, particularly in regions like North America, which holds over 42.1% of the NAC market share. The brand's product is recommended for healthy individuals 18 years and older, with a consultation advised for those with medical conditions or taking medications. For further details, visit the Nutricost NAC product page.

Nature's Way

Nature's Way is recognized as a top producer of NAC supplements, known for its high-quality and effective products. The brand ensures rigorous third-party testing and compliance with cGMP standards, similar to other leading brands like Wholesome Story and Life Extension. NAC supplements from Nature's Way are valued for their antioxidant properties and role in replenishing glutathione levels, supporting immune health, detoxification, and respiratory function. With the global NAC supplements market expected to grow at a CAGR of 8.2% from 2024 to 2030, brands like Nature's Way are poised to meet increasing demand driven by health awareness and the rising prevalence of chronic diseases. Nature's Way’s commitment to purity and efficacy aligns with consumer preferences for natural and effective health supplements. For more information, visit their NAC supplements page.