Top Folic Acid Brands for Conception Success

When embarking on the journey of trying to conceive, ensuring an adequate intake of folic acid is paramount for both aspiring mothers and their partners. Folic acid, a vital B vitamin, plays a crucial role in fetal development, reducing the risk of neural tube defects. As the market is filled with numerous brands offering folic acid supplements, it can be overwhelming to choose the right one. In this article, we will explore some of the best brands that provide high-quality folic acid supplements for couples aiming to start a family. Read on to discover which brands might suit your needs best.

Illustration of folic acid for trying to conceive

Best brands of folic acid for trying to conceive in 2025

Thorne Research

Thorne Research is a highly regarded brand for folic acid supplements, particularly for individuals trying to conceive, due to its high-quality and scientifically-backed products. Their 5-MTHF supplement is formulated to help those with genetic difficulties in converting folic acid into its active form, with up to three in five Americans benefiting from this direct supplementation. Recommended by health professionals, Thorne Research 5-MTHF supports healthy pregnancy, brain function, and heart health, and is especially crucial during the first trimester. The supplement contains 1mg of L-5-Methyltetrahydrofolate per capsule, with a suggested dose of one to three capsules daily. Thorne Research collaborates with esteemed institutions like the Mayo Clinic and has strict quality standards, ensuring reliable and effective health solutions.

Nature Made

Nature Made is a highly regarded brand for folic acid supplements, particularly for women trying to conceive, given its high-quality ingredients and strict manufacturing processes. Their Folic Acid 400 mcg Tablets are USP Verified and provide 665 mcg of folate, which is crucial for reducing the risk of neural tube defects, with only 24% of U.S. women of childbearing age meeting the recommended intake through diet alone. Nature Made's prenatal vitamins, including those with folic acid, are clinically proven for absorption and are formulated to support both the mother's and the baby's health. The brand is the #1 pharmacist-recommended letter vitamin brand, ensuring trust and reliability. These supplements are also gluten-free and lack artificial flavors, colors, and preservatives.

Garden of Life

Garden of Life is a renowned brand for prenatal supplements, particularly for those trying to conceive, due to its high-quality and nutrient-rich products. Their Organics Prenatal Once Daily Multi and Vitamin Code Raw Prenatal vitamins provide 600mcg and 800mcg of folate, respectively, which is crucial for healthy neural tube development. These supplements are made from certified organic fruits, vegetables, and herbs, ensuring easy digestion and maximum bioavailability. Additionally, they include stomach-friendly iron and probiotics for overall health and immune support. Garden of Life's commitment to using whole food fermented nutrients and avoiding synthetic binders, fillers, and artificial ingredients makes their products a trusted choice.

MegaFood

MegaFood is a reputable brand for prenatal supplements, particularly for those trying to conceive, due to its high-quality and carefully formulated products. The MegaFood Baby & Me 2 Prenatal Multi, for instance, contains methylated folate, which is crucial for preventing neural tube defects, and offers 600 mcg of folate per serving, meeting 100% of the daily value for pregnant women. This supplement also includes 300 mg of choline, exceeding the amount in leading prenatal vitamins by 2.5 times, to support fetal brain development. MegaFood's products are gluten-free, vegetarian, Non-GMO, and tested for 150 pesticides and heavy metals, ensuring safety and purity. Founded in 1973, MegaFood is a B Corp Certified company, committed to sustainability and high standards of social and environmental performance.

Solgar

Solgar is a renowned brand for producing high-quality folic acid supplements, particularly beneficial for those trying to conceive. Founded in 1947, Solgar has a long-standing commitment to using non-GMO ingredients and avoiding artificial additives, ensuring maximum bioavailability. Their folic acid supplements, such as the Solgar Folate 666mcg DFE (Folic Acid 400mcg), support healthy fetal development, heart health, and cellular function. With a strong reputation, 98% of consumers recommend Solgar products, as evidenced by a 2017 global survey. Solgar's products are crafted in small batches to ensure freshness and are produced using filtered water.

NOW Foods

NOW Foods is a reputable brand known for producing high-quality supplements, including folic acid, which is crucial for women trying to conceive to prevent neural tube defects. According to the CDC, taking 400 mcg of folic acid daily can reduce the risk of NTDs by up to 100% in women without a previous NTD-affected pregnancy. NOW Foods offers various forms of folate, including methylfolate, which is the biologically active form used in fundamental body functions like cell division and DNA synthesis. Their products ensure excellent bioavailability, which is essential for effective NTD prevention. Starting folic acid supplementation 1-3 months before pregnancy and continuing through the first trimester is highly recommended. Learn more about their methylfolate supplements.

Jarrow Formulas

Jarrow Formulas is a renowned brand for producing high-quality dietary supplements, particularly their methyl folate products, which are ideal for individuals trying to conceive. Their formulations, such as the Methyl B-12 & Methyl Folate, combine biologically active forms of vitamin B12, B9, and B6, supporting cellular energy metabolism and neurotransmitter synthesis. The methyl folate in these products is in the form of (6S)-5-MTHF, which is highly biologically active and preferable due to the body's limited ability to transform synthetic folic acid into this active form. Each serving provides 400-800 mcg of folate, equivalent to 170-680% of the Daily Value, and is free from common allergens like wheat, gluten, and dairy. Founded over 50 years ago, Jarrow Formulas is committed to superior science and quality ingredients, ensuring purity and potency in every product.

One A Day

One A Day is a reputable brand that offers high-quality folic acid supplements, particularly beneficial for women trying to conceive. Their prenatal vitamins typically contain 400 micrograms of folic acid, which is the recommended daily dose to prevent up to 70% of neural tube defects. Starting folic acid supplementation at least one month before conception and continuing through the first 12 weeks of pregnancy is crucial. One A Day's supplements are designed to support overall health and fetal development, making them a trusted choice. By taking One A Day prenatal vitamins, women can significantly reduce the risk of serious birth defects.

SmartyPants

SmartyPants is a renowned brand for prenatal vitamins, particularly notable for its use of methylated folate, a more bioavailable form of folate, which is crucial for early fetal development. Their prenatal multivitamins include over 15 premium nutrients, such as omega-3 EPA and DHA from sustainable fisheries, vitamin D3, and vitamin B12 as methylcobalamin. These gummies are non-GMO, gluten-free, and free of artificial colors or sweeteners, making them a trusted choice for women trying to conceive. SmartyPants vitamins are third-party lab tested for purity and potency, ensuring the highest quality. Based on sales data from 2022-2023, SmartyPants prenatal multivitamins contain more nutrients than leading competitors.

Nature's Way

Nature's Way is a reputable brand known for producing high-quality folic acid supplements, particularly beneficial for women trying to conceive. The brand's folic acid supplements are formulated to ensure 85% absorption, compared to the 50% absorption from natural food sources. According to the CDC, taking 400 mcg of folic acid daily, as recommended by Nature's Way, can reduce the risk of neural tube defects by up to 70%. This recommendation has been in place since the FDA mandated folic acid fortification in foods in 1998. Nature's Way's supplements are designed to support fetal health and development, making them an essential choice for women of childbearing age.