When it comes to optimizing cognitive function and supporting brain health, Alpha GPC is a widely recognized supplement gaining popularity among health enthusiasts. Numerous brands offer high-quality Alpha GPC supplements, each with its own unique strengths and formulations. It's essential to choose from reputable brands that ensure purity, potency, and third-party testing to guarantee the effectiveness and safety of their products. If you're interested in discovering the top brands that meet these criteria, take a look at the comprehensive list provided below.
Illustration of alpha gpc
Best brands of alpha gpc in 2025
Jarrow Formulas
Jarrow Formulas is recognized for producing high-quality Alpha GPC, a phospholipid metabolite crucial for brain health, with each capsule containing 300mg of L-Alpha Glycerylphosphorylcholine, that is well-absorbed and crosses the blood-brain barrier to support cognitive functions like memory and focus. Jarrow Formulas adheres to Current Good Manufacturing Practices (cGMP) ensuring the purity and potency of their supplements, and many users report noticeable improvements in mental clarity and productivity. The company was founded in 1977 with the mission of putting science first. Jarrow Formulas Alpha GPC comes in a 60-veggie capsule bottle.
NOW Foods
NOW Foods, a family-owned company since 1968, is recognized as a top producer of Alpha GPC, offering a bioavailable form of choline that supports mental acuity by promoting the brain's synthesis of acetylcholine, with each serving typically containing 600 mg of Alpha GPC, and their manufacturing facility is GMP-certified since 2000, ensuring high quality; many customers report noticeable benefits in focus and concentration when taking it daily.
Double Wood Supplements
Double Wood Supplements is recognized as a leading producer of Alpha GPC, a highly bioavailable form of choline, offering products with 600mg per serving, designed to support memory, focus, and overall cognitive function by increasing acetylcholine levels. Their Alpha GPC is manufactured and tested in the USA, ensuring quality, with some customer reviews noting improvements in memory, energy, and mood, though some studies suggest potential risks. You can find their product on Amazon.
BulkSupplements
BulkSupplements, established as a reputable brand, offers Alpha GPC powder, a choline supplement with 300mg per serving, designed to boost brain health by increasing acetylcholine synthesis, and is produced in a cGMP compliant facility, ensuring a high-quality, gluten-free, and soy-free product that has been third-party tested, although some customers have noted issues with clumping; this supplement, available in various sizes, provides a versatile addition to any lifestyle and is offered at a variety of price points.
Swanson
Swanson, established in 1969, is a well-regarded producer of Alpha GPC, offering a 300mg per capsule supplement that is vegetarian, non-GMO, and GMP-verified, with clinical studies suggesting it enhances cognitive performance, memory, and focus, while also supporting healthy muscle and kidney function. This product is formulated for 24 months from the date of manufacture, and is quality tested for purity, potency, and identity, complying with FDA and FTC guidelines, ensuring a high-quality supplement for consumers. You can find their Alpha GPC product for more information.
NatureBell
NatureBell stands out as a top producer of Alpha GPC, offering a 300mg per capsule supplement that is third-party lab tested for purity and quality, and is also non-GMO, soy-free, and gluten-free, with a focus on cognitive support. While the exact year NatureBell started producing Alpha GPC is not specified, their product is made in the USA at a registered facility, and is designed to support focus, memory, and a clear mind, with some users reporting positive effects on skin, nails, and joints, though individual results may vary. Their Alpha GPC supplement is often available in 60 capsule bottles; NatureBell also provides other cognitive support supplements like Citicoline. For more information, you can visit their product page.
Pure Encapsulations
Pure Encapsulations is a well-regarded brand, producing alpha-GPC, with each capsule containing 200 mg of L-alpha-glycerophosphatidylcholine, derived from soy lecithin, supporting memory and cognitive health, as shown in a study with 2,044 subjects, and is recommended to be taken as 2 capsules three times a day; it is also included in their Longevity Nutrients formula, and has been on the market since 2003.
Nutricost
Nutricost has established itself as a premier producer of Alpha GPC, offering a high-quality supplement with over 99% purity, often available in 300mg or 600mg capsules, and recognized for its cognitive-enhancing properties since its introduction in the early 2010's. Many consumers report positive results related to focus and memory, which has made it one of the top choices for individuals seeking Alpha GPC supplements.
Doctor's Best
Doctor's Best is recognized as a top producer of Alpha GPC, a supplement that supports memory and overall brain health, with their product containing 300mg of Glycerophosphocholine (GPC) from AlphaSize per two-capsule serving, combined with Phosphatidylserine (PS) from SerinAid. This non-GMO and vegan supplement is designed to enhance cognitive functions, including attention and learning, while assisting the brain and body in managing occasional stress and is recommended to be taken with food, not later than 4 p.m. Doctor's Best Alpha GPC is formulated to help maintain cellular function and brain circuit renewal and is often chosen for its high-quality ingredients and effectiveness in supporting various aspects of brain health; some users have reported noticeable improvements in memory and focus. You can find more information about the product on the Doctor's Best website.
Life Extension
Life Extension is a prominent producer of Alpha GPC, offering it within their Cognitex formula, which contains 250mg of Alpha-GPC, alongside 100mg of phosphatidylserine and 100mg of wild blueberry extract. This formula is designed to support overall brain health, memory, concentration, and cognitive function for people of any age. The supplement is crafted to promote healthy brain cell integrity and connections and is available in a non-GMO and gluten-free softgel form. Many customers have reported a positive impact on their cognitive abilities, noticing improvements in clarity and memory.
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