Top Nitric Oxide Supplement Brands for Peak Performance

Nitric oxide supplements have gained popularity for their potential benefits in enhancing athletic performance and promoting cardiovascular health. With an increasing demand, various brands have emerged, each offering unique formulations aimed at optimizing nitric oxide levels in the body. Some top contenders in the market include well-known names that focus on ingredient transparency, scientific backing, and consumer feedback. To discover the best brands leading in nitric oxide supplementation, explore the comprehensive list below.

Illustration of nitric oxide

Best brands of nitric oxide in 2025

HumanN

HumanN is a leading brand in the production of nitric oxide boosters, with products like SuperBeets and Neo40 that have been clinically studied and proven to enhance nitric oxide levels. These products utilize the nitrate-nitrite-NO pathway, with SuperBeets converting about 5% of ingested nitrate to nitrite, which is then reduced to nitric oxide, contributing to less than 10% of the body's total NO production but playing a crucial complementary role. Neo40, in particular, uses a patented formula with 15-20 mg of supplemental sodium nitrite to improve cardiovascular risk factors and reduce blood pressure, as demonstrated in studies showing a 10.9% decrease in carotid intima-media thickness (CIMT) over six months.

Snap Supplements

Snap Supplements stands out as a leading producer of nitric oxide boosters, formulated with essential amino acids like L-Citrulline and L-Arginine, which are powerful precursors to nitric oxide production. Their supplements are designed to support heart health, enhance lung function, and naturally boost energy levels without stimulants or added sugars. Backed by scientific studies, these supplements ensure adequate nitric oxide levels to relieve stress and support healthy blood flow. With a 90-day money-back guarantee, Snap Supplements commits to providing high-quality, natural ingredients that have been scientifically proven to produce real results. Their products are free from common allergens, sugar, and caffeine, making them a reliable choice for those seeking consistent energy and improved circulatory health.

Berkeley Life

Berkeley Life is a leading brand in nitric oxide supplementation, renowned for its clinically proven products that boost nitric oxide levels, particularly beneficial for cardiovascular health and overall vitality. Their supplements, such as the Nitric Oxide Foundation, are formulated with potent dietary nitrates equivalent to those found in leafy greens and beets, and have been shown to lower systolic and diastolic blood pressure and improve endothelial function. The brand's products are gluten-free, dairy-free, and vegan, manufactured in FDA-inspected facilities in the U.S.A. Berkeley Life's commitment to research is evident in their collaboration with over 1,500 healthcare practitioners and the inclusion of non-invasive salivary test strips to monitor nitric oxide levels. Their products have garnered over 1,000 verified 5-star ratings, underscoring their effectiveness.

Zhou Nutrition

Zhou Nutrition is renowned for its premium nitric oxide boosters, particularly the N.O. Pro formula, which has been available since April 2018. This supplement is scientifically formulated with a unique blend of L-Arginine HCl, Arginine alpha-ketoglutarate (AAKG), Citrulline Malate, and Beet Root to enhance muscle strength, energy, endurance, and recovery. Each serving of four capsules contains 1200 mg of L-Arginine HCl and AAKG, 610 mg of Citrulline Malate, and 160 mg of Beet Root. The product is vegan, gluten-free, and made with non-GMO ingredients, ensuring a clean and effective formula. With 30 servings per container, Zhou Nutrition's N.O. Pro is a trusted choice among athletes and fitness enthusiasts.

Force Factor

Force Factor is a leading brand in the production of nitric oxide boosters, offering a range of supplements designed to enhance athletic performance and overall health. Their products, such as Total Beets and VolcaNO Extreme, utilize natural ingredients like beetroot and L-citrulline to boost nitric oxide production, improving blood flow and endurance. VolcaNO Extreme, in particular, combines L-citrulline with Nitrosigine® and CON-CRET® creatine to provide a premium pump and enhanced mental focus, with effects lasting up to 6 hours. These formulations are scientifically engineered to deliver extreme energy, strength, and recovery benefits, making them a favorite among serious weightlifters. By incorporating clinically tested ingredients, Force Factor ensures optimal absorption and efficacy.

Cellucor

Cellucor is renowned as one of the top producers of nitric oxide supplements, particularly with their NO3 Chrome product, which has been enhancing athletic performance for nearly a decade. Founded in 2009, Cellucor has consistently delivered high-quality, stimulant-free supplements that promote increased nitric oxide production, blood flow, and powerful pumps. The NO3 Chrome features clinically studied ingredients like Nitrosigine and Arginine Nitrate, and each serving costs $1.10, or as low as $0.77 with the subscribe and save option. This supplement is recommended by athletes such as Demi Bagby and Scott Mathison, and it is engineered to be used at any time of the day, including evening training. With a 30-day supply in each tub of 90 capsules, Cellucor NO3 Chrome is a reliable choice for those seeking to improve muscular performance and hypertrophy.

Horbäach

Horbaach is a renowned brand for nitric oxide supplements, offering a range of products that cater to athletes and casual gym-goers alike. Their Nitric Oxide Max 3000mg supplement features 2,000 mg of L-Citrulline and 1,000 mg of L-Arginine per serving, making it a potent dual-action formula for enhancing workout performance. Additionally, their Nitric Oxide Max Beet Root capsules provide 3,000 mg per serving of a Nitric Oxide Precursor Blend, including beet root, grape seed, and black pepper extract, along with vitamins C and B. These supplements are designed to boost nitric oxide levels, improving blood flow and exercise performance. Horbaach's products are gluten-free, non-GMO, and made without artificial flavor or sweetener, ensuring high-quality support for daily routines. For more details, check out their Nitric Oxide Booster.

GNC

GNC is renowned as one of the top producers of nitric oxide supplements, offering high-quality formulas that enhance blood flow and muscle growth. Their supplements, often containing L-arginine and L-citrulline, are designed to boost fitness performance and heart health, although research on their efficacy is mixed. GNC's products are popular among athletes and fitness enthusiasts, with some studies suggesting improvements in endurance and aerobic performance. However, it is crucial to consult medical advice before using these supplements, especially for individuals with certain health conditions. GNC's commitment to quality and customer satisfaction has made their nitric oxide supplements a trusted choice in the market.

Evlution

EVLution Nutrition is renowned for producing top-tier nitric oxide boosters, such as PumpMode, which utilizes advanced ingredients like NO3T Betaine Nitrate to enhance blood flow and muscle hydration by up to 10 times the concentration of conventional glycerol products. This results in intensified muscle pumps, improved vascularity, and enhanced endurance. The formula includes powerful antioxidants like Vitamin C and D to sustain nitric oxide levels and support overall muscle health. PumpMode is designed to be stimulant-free, making it ideal for various training regimens. By increasing nitric oxide production, EVLution Nutrition's products help deliver more nutrients and oxygen to the muscles, thereby boosting performance and recovery.

Jarrow Formulas

Jarrow Formulas is renowned for its high-quality supplements, particularly in the realm of nitric oxide production. The brand's Arginine-Citrulline Sustain(tm) product combines sustained-release arginine and citrulline to support vascular health and promote blood flow. In 2019, Jarrow Formulas was chosen as the #1 Probiotics Brand for customer satisfaction by ConsumerLab.com, reflecting its commitment to superior science and customer trust. With over 30 years of experience in probiotics and a focus on clinically documented strains, Jarrow Formulas ensures purity, potency, and effectiveness in its products. This expertise extends to its nitric oxide supplements, making it a reliable choice for those seeking to boost nitric oxide production.