Top Nicotinamide Brands: Discover the Best in Skin & Health!

Nicotinamide, a form of Vitamin B3, has gained popularity for its potential health and beauty benefits, prompting numerous brands to enter the market with their unique formulations. Some of the leading names include Tru Niagen, Life Extension, and Thorne Research, each offering distinct advantages like purity, dosage, and availability. Additionally, brands like Solgar and NOW Foods have also established a strong reputation for their quality supplements, appealing to consumers seeking effective and reliable options. To explore a more comprehensive list and details about these best brands, continue reading below.

Illustration of nicotinamide

Best brands of nicotinamide in 2025

Life Extension

Life Extension is a leading brand in producing high-quality nicotinamide riboside supplements, such as their NAD+ Cell Regenerator™, which has been shown to increase NAD+ levels by 51% in a 2019 randomized controlled trial. This supplement, featuring NIAGEN®, supports cellular energy production and metabolism, contributing to healthy aging and enhanced energy levels. Nicotinamide riboside has also demonstrated potential in extending lifespan, with studies showing a 5% increase in the lifespan of old mice, equivalent to about four additional years of human life based on current life expectancy. The combination of nicotinamide riboside with other bioavailable nutrients like resveratrol, quercetin, and fisetin further enhances its benefits. Life Extension's products are highly praised for their effectiveness in promoting cellular health and overall well-being.

Thorne Research

Thorne Research is a leading brand in producing high-quality nicotinamide riboside supplements, having achieved self-affirmed GRAS (Generally Recognized as Safe) status for its proprietary nicotinamide riboside malate (NRM) product in 2022. This status is a result of extensive quality and safety testing, as well as review by an independent expert panel, ensuring the product's quality, safety, and purity are equal to or superior to other forms of nicotinamide riboside. Thorne's NRM is also NSF Certified for Sport(r), guaranteeing the highest level of safety and testing. The product, such as NiaCel 400, supports cellular health, promotes NAD+ production, and enhances athletic performance. With over four million customers and collaborations with Mayo Clinic, Thorne HealthTech is trusted for its innovative and science-driven health solutions.

Elysium Basis

Elysium Health's Basis is a leading supplement in the field of aging research, clinically proven to increase NAD+ levels by an average of 40% in a double-blind, randomized, placebo-controlled clinical trial published in Nature Partner Journals: Aging and Mechanisms of Disease in 2017. Basis combines Elysium's proprietary nicotinamide riboside (NR-E) with the antioxidant pterostilbene, demonstrating significant benefits in cellular energy, mitochondrial function, and protection against oxidative stress. The supplement has also shown positive results in reducing markers of liver inflammation in individuals with non-alcoholic fatty liver disease (NAFLD), as reported in a study published in Hepatology in 2022. Basis is third-party tested for purity and quality and is NSF Certified for Sport. This rigorous commitment to research and quality sets Basis apart as a superior NAD+ supplement. For more information, visit their official website.

Tru Niagen

Tru Niagen, produced by ChromaDex, is a leading brand in nicotinamide riboside (NR) supplementation, clinically proven to increase NAD+ levels by up to 150% and support mitochondrial health and cellular energy production. With over 40 registered clinical trials and more than 100 preclinical studies, Niagen® has been validated for its safety and efficacy by regulatory bodies worldwide, including the FDA, European Commission, and Health Canada. The supplement has been shown to safely elevate NAD+ levels in various studies, including a 2019 clinical trial where 300mg of Niagen® increased NAD+ levels by 40-50% in healthy overweight adults. Tru Niagen stands out for its patented and broadly studied NR, making it a gold-standard in NAD+ research and supplementation. The company's dedication to ongoing research ensures continuous improvement in their products.

NOW Foods

NOW Foods is a reputable brand known for producing high-quality nicotinamide supplements, which are essential for various health benefits, including metabolism and skin health. Their niacinamide products, such as the 500 mg veg capsules, support the body's metabolism of proteins, fats, and carbohydrates, and aid in normal growth and development. With a strong presence in the market, NOW Foods ensures that their products are quality-tested to empower individuals to lead healthier lives. The brand's commitment to natural and effective supplements has made it a trusted choice for many consumers. For instance, their niacinamide capsules are available in 100-count servings, making them a convenient and affordable option.

Doctor's Best

Doctor's Best is a renowned brand in the supplement industry, particularly noted for its high-quality nicotinamide mononucleotide (NMN) products. In 2020, their NMN supplement achieved significant success in China, selling over 5,000 bottles and generating US$1 million in sales within the first 10 days of its launch. Each capsule contains 400mg of NMN, supporting NAD+ production and energy metabolism. The product is made in the US, ensuring compliance with stringent manufacturing standards, and is available in delayed-release vegetarian capsules. Doctor's Best NMN has garnered attention for its potential in addressing the aging process and supporting overall vitality.

Jarrow Formulas

Jarrow Formulas is a renowned brand in the nutritional supplement industry, particularly noted for its high-quality nicotinamide products. Their Nicotinamide Mononucleotide (NMN) supplement, available in 125mg tablets, is designed to support cellular energy production and mitochondrial function by serving as a precursor to NAD+, a metabolite of vitamin B3 that declines with aging and high caloric intake. Jarrow Formulas ensures the purity and potency of their products by adhering to Current Good Manufacturing Practices (cGMP) and collaborating with global researchers and institutions. Their formulations are backed by strong scientific research, as evidenced by their clinical studies, such as the one demonstrating the superior bioavailability of their QH-absorb(r) formula in 2009. This commitment to science and quality makes Jarrow Formulas a trusted name in the health and wellness sector.

Pure Encapsulations

Pure Encapsulations is a renowned brand in the supplement industry, particularly for its high-quality niacinamide products. With over 30 years of research and innovation, they formulate supplements using pure, vegan-friendly ingredients, free from common allergens and unnecessary additives. Their niacinamide supplements support energy metabolism, glucose balance, and joint health, and are backed by verifiable science from multiple clinical studies. Each product is manufactured in an NSF-GMP registered facility, ensuring strict quality control and potency. Pure Encapsulations sources premium raw materials from trusted suppliers worldwide, adhering to rigorous testing and quality criteria.

Solgar

Solgar, a renowned brand under Nestle Health Science, stands out as a leading producer of nicotinamide riboside (NR) supplements, particularly through their Cellular Nutrition collection. Their Cellular Energy capsules feature ChromaDex's patented NIAGEN(r) NR, clinically shown to increase NAD+ levels by over 50% in as little as two weeks, backed by 30+ human clinical studies and 300 published scientific studies. This collaboration marks a significant milestone, combining Solgar's scientific rigor with ChromaDex's industry-leading NAD+ research. The supplement contains 300mg of NIAGEN NR, supporting cell energy, repair, and vitality. This partnership was announced in April 2024, reinforcing Solgar's commitment to healthy aging.

Garden of Life

Garden of Life is renowned for its high-quality supplements, including those containing nicotinamide, ensuring strict adherence to USDA Organic and Non-GMO Project Verified standards. The brand's commitment to transparency and third-party testing, such as certifications from NSF and Informed-Choice, guarantees the purity and efficacy of their products. Garden of Life sources ingredients globally, including from the USA, Canada, and Germany, and manufactures all products in the United States. Their supplements, like the Dr. Formulated Once Daily Men's Probiotics, have garnered over 10,000 reviews on Amazon with a 78% 5-star rating, reflecting customer satisfaction. The brand's dedication to quality and safety makes it a trusted choice for health enthusiasts.