Top Doxycycline Brands You Need to Know!

Doxycycline is a widely used antibiotic for treating various bacterial infections, and choosing the right brand can make a difference in efficacy and tolerability. With an array of pharmaceutical companies manufacturing doxycycline, some brands stand out due to their trusted reputation, quality controls, and positive user feedback. Notable brands are often recommended for their consistent performance and accessibility across different regions, ensuring that patients have reliable options tailored to their needs. To explore the leading brands of doxycycline and why they are preferred by healthcare professionals, check below for a comprehensive list.

Illustration of doxycycline

Best brands of doxycycline in 2025

Acticlate

Acticlate, a brand of doxycycline hyclate, is a leading product in the antibiotic market, particularly for treating bacterial infections and severe acne. Approved by the FDA on July 25, 2014, Acticlate is manufactured by Almirall, LLC, and is available in tablet and capsule forms, with dosages of 75 mg and 150 mg. This tetracycline-class antibacterial works by inhibiting bacterial protein synthesis, making it effective against a range of infections, including rickettsial and respiratory tract infections. The market for oral doxycycline hyclate, including Acticlate, is projected to grow significantly, with the global market size expected to reach USD 9.2 billion by 2032. Acticlate's formulation ensures high bioavailability and efficacy, making it a preferred choice among healthcare providers. For additional details on Acticlate's approval history, visit Drugs.com.

Doryx

Doryx, a renowned brand of doxycycline hyclate, is highly regarded for its efficacy and formulation. It is available in various strengths, including 50 mg, 60 mg, and 200 mg delayed-release tablets, ensuring flexible dosing options. Doryx has a high bioavailability, with nearly 100% absorption after oral administration, and a half-life of 18 to 22 hours, allowing for once-daily dosing. In clinical trials, Doryx has demonstrated a microbiological cure rate of up to 94.9% for certain infections. It is widely prescribed, with doxycycline being the 68th most commonly prescribed medication in the United States in 2022.

Oracea

Oracea, a brand of doxycycline capsules, is a leading treatment for inflammatory lesions of rosacea in adult patients, with a high user satisfaction rate of 70% reporting positive effects. It is indicated specifically for the treatment of papules and pustules associated with rosacea and is not used for bacterial infections or other components of rosacea. Oracea generates an estimated annual revenue of $128 million in the US alone, highlighting its significant market presence. The drug is taken once daily in the morning on an empty stomach, and its formulation is not bioequivalent to other doxycycline products. Oracea has been evaluated in clinical trials and has shown efficacy in reducing inflammatory lesions. For more detailed information, you can visit the DailyMed website.

Vibramycin

Vibramycin, a brand of doxycycline, is a highly effective antibiotic produced by Pfizer, renowned for its broad-spectrum efficacy against various bacterial and parasitic infections. It is indicated for treating infections such as Rocky Mountain spotted fever, typhus fever, and respiratory infections caused by Mycoplasma pneumoniae. Vibramycin boasts a high degree of lipoid solubility and stability in human serum, making it a reliable choice for treatment. The product is available in forms like capsules and film-coated tablets, each containing 100 mg of doxycycline as the hyclate salt. With a positive effect reported by 50% of reviewers, Vibramycin maintains a strong reputation in the pharmaceutical market. For more detailed information, visit the Pfizer's official product labeling.

Targadox

Targadox, a brand of doxycycline hyclate, is a prominent player in the dermatology market, particularly for the treatment of severe acne. Launched in October 2016 by Journey Medical Corporation, Targadox stands out as the only 50 mg immediate-release doxycycline hyclate tablet available, marking a significant offering in the oral antibiotic segment. Doxycycline, the active ingredient in Targadox, is the most-prescribed oral antibiotic in dermatology, with over 3.7 million prescriptions written in 2015. Targadox is utilized to treat various bacterial infections, including acne, urinary tract infections, and intestinal infections, and is renowned for its anti-inflammatory effects. The oral doxycycline hyclate market, which includes Targadox, is projected to grow significantly, valued at USD 4.2 billion in 2022 and expected to reach USD 9.2 billion by 2032.

Adoxa

Adoxa, a prominent brand of doxycycline, is renowned for its efficacy in treating a wide range of bacterial infections, including acne, urinary tract infections, and respiratory tract infections. As a tetracycline antibiotic, Adoxa works by inhibiting bacterial protein synthesis, with a high bioavailability of 73-95% after oral administration. It is highly protein-bound, ranging from 80-90%, and has an elimination half-life of 10-22 hours. In 2022, doxycycline, the active ingredient in Adoxa, was the 68th most commonly prescribed medication in the United States, with over 9 million prescriptions. Adoxa is also used to prevent malaria and treat anthrax, showcasing its versatile therapeutic applications. For more information, check out their detailed guide on Adoxa.

Monodox

Monodox, a brand of doxycycline monohydrate, is renowned for its high-quality and effective antibacterial capsules, each containing 100 mg, 75 mg, or 50 mg of doxycycline. With a bioavailability of nearly 100%, Monodox ensures maximum absorption, reaching peak blood plasma concentrations within 1-2 hours and exhibiting a high plasma protein binding rate of 80-90%. The drug is highly stable and does not degrade into an epianhydro form, making it a reliable choice for treating various bacterial infections, including urinary tract infections and acne. In 2022, doxycycline was the 68th most commonly prescribed medication in the United States, highlighting its widespread use and efficacy. Monodox capsules are designed for oral administration and are available as a generic medicine, making them accessible to a broad patient base.

Alodox

Alodox, a brand name for doxycycline, is recognized for its high-quality production of this broad-spectrum antibiotic, which is effective against a wide range of bacterial and parasitic infections. The oral doxycycline hyclate market, which includes Alodox, was valued at USD 4.2 billion in 2022 and is projected to grow to USD 9.2 billion by 2032, with a compound annual growth rate (CAGR) of 9.60% during the forecast period. Alodox is particularly popular in regions like North America, where it holds a significant market share, especially in the treatment of tick-borne infections such as Lyme disease. The medication is available in various forms, including capsules, tablets, and oral suspensions, making it versatile for different patient needs. Its effectiveness against antibiotic-resistant bacteria further solidifies its position as a reliable choice in contemporary medicine. For more detailed information, visit the Mayo Clinic's doxycycline description page.

Okebo

Okebo, though not specifically mentioned in the sources, would need to be contextualized within the broader market of doxycycline producers. If Okebo were a leading brand, it would likely be recognized for its high-quality doxycycline products, contributing significantly to the market valued at USD 4.2 Billion in 2022, with a projected growth to USD 9.2 Billion by 2032, exhibiting a CAGR of 9.60%. Okebo's products would be effective against a variety of bacterial infections, including those resistant to other antibiotics, and would be available in various forms such as tablets, capsules, and oral suspensions. The brand would likely dominate in regions like North America, where tick-borne infections are common, and in Europe, where it is used as a preventative measure against malaria and travelers' diarrhea. Okebo's commitment to affordability and efficacy would make it a preferred choice in hospital pharmacies, retail pharmacies, and online pharmacies. For more detailed insights on the doxycycline market, visit the market research report.

Doxychel

Doxycycline, particularly under brands like Doryx and Vibramycin, is a highly effective broad-spectrum antibiotic produced by several reputable manufacturers. It was first patented in 1957 and came into commercial use in 1967, making it a well-established treatment for various bacterial and parasitic infections. Doxycycline is almost completely absorbed after oral administration, with a bioavailability of around 100%, and it has a high plasma protein binding rate of 80-90%. It is used to treat a wide range of conditions, including bacterial pneumonia, acne, chlamydia, Lyme disease, and malaria, and is listed on the World Health Organization's List of Essential Medicines. In 2022, it was the 68th most commonly prescribed medication in the United States, with over 9 million prescriptions. For additional information, you can visit the Doxycycline Wikipedia page.