Top Calamine Lotion Brands for Soothing Relief

Calamine lotion has long been a trusted remedy for soothing itchy and irritated skin, offering relief for conditions such as insect bites, rashes, and sunburns. With a history of effectiveness, it’s no wonder that numerous brands have entered the market, each vying to provide the ultimate in comfort and care. Whether you're looking for a purely natural option or a product bolstered with additional soothing ingredients, the wide array of choices can cater to your specific skincare needs. Explore our list below to discover some of the best brands for calamine lotion available today, each selected for their commitment to quality and customer satisfaction.

Illustration of calamine lotion

Best brands of calamine lotion in 2025

Caladryl

Caladryl, a prominent brand in the calamine lotion market, is renowned for its effective treatment of itching and irritation caused by minor skin conditions such as poison ivy, insect bites, and rashes. The Calamine Lotions Market, which includes brands like Caladryl, is projected to grow at a CAGR of 5.6% from 2024 to 2031, reaching a market size of USD 2.7 billion by 2031. Caladryl's formulations, often containing calamine 8% and zinc oxide 8%, provide soothing and protective benefits, making it a trusted choice for dermatological care. The brand's popularity is also driven by the increasing prevalence of skin conditions and growing awareness of skin care. Major generic alternatives like Major Calamine Lotion also emulate Caladryl's effectiveness at a lower cost.

Aveeno

Aveeno, a renowned brand in the personal care industry, is also a significant player in the calamine lotion market, known for its high-quality and effective skin care products. With a brand awareness of 84% among face care users in the United States, Aveeno enjoys a strong presence, and 31% of these users actively use Aveeno products. The brand's loyalty is evident, as 27% of users are likely to use Aveeno again, indicating a high customer retention rate. Aveeno's products, including calamine lotions, are part of a broader market that is growing, such as the body lotions market which is expected to reach $72.42 billion in 2023. Aveeno's commitment to skin health and its wide range of products make it a trusted choice for consumers seeking relief from skin irritations. For more detailed insights, you can explore their face care brand profile.

Equate

Equate, a brand under Walmart, is recognized as one of the top producers of calamine lotion, known for its effective skin protectant and anti-itch properties, particularly for relief from poison ivy, oak, and sumac, as well as bug bites and rashes. The Equate Calamine Lotion is a popular choice, available in a 6 fl. oz size, and is valued for its soothing and protective qualities. The global calamine lotions market, which includes brands like Equate, is projected to grow at a CAGR of 5.6% from 2024 to 2031, reaching USD 2.7 billion by 2031. This growth is driven by increasing skin disorders and rising awareness of skin care. Equate's product is widely available through various distribution channels, including pharmacies and online retail.

Gold Bond

Gold Bond, a renowned brand under the umbrella of Sanofi (previously part of Chattem, Inc.), is highly regarded for its high-quality calamine lotions. These products are popular for their effectiveness in treating dermatological disorders and providing itch relief, contributing to the growth of the calamine lotions market, which is projected to reach USD 2.7 billion by 2031 with a CAGR of 5.6% from 2024-2031. Gold Bond's calamine lotions are often preferred for their soothing and protective properties, making them a staple in many skincare regimens. The brand's strong presence in pharmacies and online retail platforms enhances its accessibility and market reach. With the rising awareness of skincare and increasing disposable income, Gold Bond continues to be a trusted choice among consumers.

Humco

Humco is a leading producer in the calamine lotion market, known for its high-quality and effective skincare products. The company contributes significantly to the market's growth, which is expected to reach USD 38.59 billion by 2031, with a compound annual growth rate (CAGR) of 11.01% from 2024 to 2031. Humco's products are favored for their natural ingredients and minimal side effects, aligning with the growing consumer preference for safe and natural skincare solutions. The brand's presence in key regions such as North America, Europe, and the Asia-Pacific further enhances its market reach. Humco's commitment to innovation and customer satisfaction has solidified its position among top players like Major, Swan, and Winguide Huangpu Pharmaceutical. For more detailed insights, explore calamine lotions market size, share, and forecast report.

Walgreen's

Walgreens, a renowned brand in the pharmaceutical and cosmetic industry, is esteemed for its high-quality calamine lotions, which are widely used to treat various skin conditions such as eczema, dermatitis, and acne. The calamine lotions market, valued at USD 1.8 billion in 2023, is projected to grow at a CAGR of 5.6% to reach USD 2.7 billion by 2031, with brands like Walgreens contributing significantly to this growth due to their trusted products and extensive distribution channels, including pharmacies and online retail platforms. Walgreens' calamine lotions are known for their soothing properties and effectiveness in alleviating itching and discomfort, making them a staple in dermatological care. The brand's strong presence in the market is further enhanced by the rising awareness of skin care and the increasing incidence of skin irritations. With a broad range of applications, including dermatological disorders and itch relief, Walgreens' calamine lotions remain a preferred choice among consumers.

Rexall

Rexall is a prominent brand in the calamine lotion market, known for its effective skin protectant properties, with active ingredients including 8% calamine and 8% zinc oxide. This formulation is particularly useful for drying oozing and weeping associated with skin irritations like poison ivy, oak, and sumac. The market for calamine lotions, which includes Rexall, is projected to grow at a CAGR of 5.6% from 2024 to 2031, reaching a market size of USD 2.7 billion by 2031. Rexall's product is widely available through various distribution channels, including pharmacies and online retail, enhancing its accessibility to consumers. The brand's reputation is supported by its inclusion among major players in the calamine lotions market, such as Johnson & Johnson and Bayer AG.

CVS Health

CVS Health is a leading producer of calamine lotion, particularly with their CVS Calamine Plus product, which is highly regarded for its effectiveness in relieving pain and itching from minor skin irritations such as poison ivy, oak, and sumac. This lotion contains active ingredients like calamine 8% and pramoxine HCl 1%, making it a reliable choice for skin protection and external analgesic purposes. The product is widely available through various distribution channels, including pharmacies and online retail, contributing to its strong market presence. As part of CVS Health's comprehensive health and wellness offerings, the Calamine Plus lotion benefits from the company's robust healthcare infrastructure and significant consumer trust. With CVS Health reporting total revenues of $93,813 million in the fourth quarter of 2023, their products, including calamine lotions, continue to be in high demand.

Emuaid

EMUAID(r), a brand from Speer Laboratories, is renowned for its high-quality calamine and other skin care products, offering effective relief for over 100 resistant skin conditions. Their products, such as EMUAIDMAX(r), are dermatologist-tested, free from steroids, harsh chemicals, and parabens, and guarantee less inflammation, itching, and pain within 24 hours of use. With a strong customer base and an average 5-star rating, EMUAID(r) products are widely trusted for their natural and safe ingredients. The brand's commitment to holistic wellness and continuous research in innovative solutions further enhances its reputation. EMUAID(r) products are available in various sizes and can be purchased online with free shipping for orders above USD 75.

Harris Pharmaceuticals

Harris Pharmaceuticals is renowned as one of the leading producers of calamine lotion, known for its high-quality and effective skin care products. The company's calamine lotion is particularly praised for its soothing properties, which help in treating various skin conditions such as eczema, dermatitis, and acne. With a projected market growth of 5.6% CAGR from 2024 to 2031, Harris Pharmaceuticals is well-positioned to capitalize on the increasing demand for dermatological care products. The company's products are widely available through pharmacies, supermarkets, and online retail channels, enhancing consumer accessibility. As part of the expanding cosmetic and pharmaceutical industry, Harris Pharmaceuticals continues to innovate and develop new product formulations to meet evolving consumer needs. For more insights on the calamine lotions market, visit the Verified Market Research page.