Top Amoxicillin-Clavulanic Acid Brands You Need to Know

When it comes to treating bacterial infections, amoxicillin combined with clavulanic acid is a widely trusted antibiotic due to its effectiveness in overcoming resistance. Selecting the right brand can make a significant difference in aspects such as tolerability, formulation, and cost. Some brands have consistently stood out for their superior quality and manufacturing standards. In the following sections, we will explore some of the most reputable brands that offer amoxicillin and clavulanic acid, ensuring you have the information needed to make an informed choice.

Illustration of amoxicillin, clavulanic acid

Best brands of amoxicillin, clavulanic acid in 2025

Augmentin

Augmentin, a well-known brand, combines amoxicillin, a penicillin-type antibiotic, with clavulanic acid, a beta-lactamase inhibitor, enhancing its effectiveness against a broad spectrum of bacteria, including those resistant to amoxicillin alone, with amoxicillin to clavulanic acid ratios varying from 16:1 to 2:1, and it is available in multiple forms, such as tablets and oral suspensions, with common dosages including 500mg/125mg and 250mg/62.5mg per tablet or 5ml respectively. Augmentin is used to treat various infections, such as respiratory, urinary tract, skin and soft tissue, and dental infections and is available under various names like Augmentan, Clavamox and Clavulin. You can find more details about their product on GSKPro's official website.

Clavamox

Clavamox, a trusted veterinary antibiotic for over 30 years, combines amoxicillin, a penicillin-type antibiotic, with clavulanic acid, a beta-lactamase inhibitor, to effectively combat a range of bacterial infections in dogs and cats, including skin, soft tissue, and periodontal issues, and is also used off-label for urinary tract infections. This formulation enhances amoxicillin's efficacy by preventing its breakdown by bacterial enzymes, and it is available in chewable tablets and liquid suspensions. Clavamox is often prescribed by veterinarians and, while generally safe, overdoses may cause vomiting or diarrhea. It's crucial to consult a vet for proper use and dosage. For more detailed information, visit the Zoetis Petcare website.

Amoclan

Amoclan, a brand by Hikma Pharmaceuticals, is a widely recognized producer of amoxicillin and clavulanic acid, a combination antibiotic used to treat various bacterial infections, with the clavulanic acid component acting as a beta-lactamase inhibitor, enhancing the effectiveness of amoxicillin; this combination is frequently used, with global sales of clavulanic acid projected to reach $777.66 million by 2034, demonstrating its significance in fighting antibiotic resistance. Amoclan is available in multiple dosage forms, including tablets and suspensions, and is prescribed for infections like otitis media, pneumonia, and urinary tract infections, making it a versatile option for both adults and children. While Amoclan is a common brand, it's crucial to be aware of potential side effects, such as diarrhea and allergic reactions, and to consult a healthcare provider before use.

Co-amoxiclav

Co-amoxiclav, a widely recognized brand, is a prominent producer of amoxicillin and clavulanic acid, combining these two active ingredients to combat bacterial infections; the typical ratio of amoxicillin to clavulanic acid in tablets is 500mg to 125mg, and it is also available in various forms like oral suspensions with ratios such as 400mg to 57mg per 5ml. Amoxicillin, a penicillin-type antibiotic, is made more effective with clavulanic acid, which inhibits bacterial resistance, and a notable amount, approximately 60-70% of amoxicillin and 40-65% of clavulanic acid, is excreted through urine within 6 hours after administration. Co-amoxiclav is used to treat a wide array of infections including respiratory tract, urinary tract, skin, and dental infections. You can find more information about Co-amoxiclav.

Clavulin

Clavulin, a well-known brand, is a reliable producer of amoxicillin and clavulanic acid combinations, with formulations like 200 mg of amoxicillin and 28.5 mg of clavulanic acid per 5mL in some suspensions, and is used to treat various bacterial infections such as those of the skin and the urinary tract, and is available in both oral and intravenous forms; this combination medication, which includes a beta-lactamase inhibitor, is often prescribed in accordance with local antibiotic guidelines to ensure appropriate use, with treatment duration not exceeding 14 days without review. For more detailed product information, you can visit their website.

Curam

Curam, a leading brand in antibiotic production, is highly regarded for its amoxicillin and clavulanic acid combination, with studies showing a 90% effectiveness rate in treating common bacterial infections since 2001; its formulations, available in various strengths, are widely prescribed by doctors worldwide and known for their quality and consistent results. The brand has maintained a top position for its production of these essential medications, continually undergoing quality checks to ensure patient safety and efficacy. With a 20-year track record, Curam has become a trusted name in healthcare, providing reliable treatment options. Its ongoing commitment to innovation and quality positions it as a key player in the pharmaceutical industry.

Synermox

Synermox, produced by Douglas Pharmaceuticals, is a brand of amoxicillin and clavulanic acid, a combination antibiotic used to treat various bacterial infections, including those of the ears, lungs, sinuses, and skin; the product is expected to be listed in New Zealand on February 1, 2025. This combination therapy works by using clavulanic acid to prevent bacteria from deactivating amoxicillin, enhancing its effectiveness against beta-lactamase producing organisms. Synermox is available in various formulations, including film-coated tablets and powder for oral suspension, with the amoxicillin to clavulanic acid ratio typically varying depending on the manufacturer, commonly in ratios such as 8:1 or 7:1. More information about the product can be found on the website for Pharmac, the New Zealand government's pharmaceutical funding agency.

Amoxiclav

Amoxiclav, a brand known for its amoxicillin and clavulanic acid combination, was first patented in 1977 and launched in the UK in 1981, effectively combining amoxicillin, an antibiotic, with clavulanic acid, a beta-lactamase inhibitor, which prevents the breakdown of amoxicillin by certain bacteria; typically, a 500mg/125mg tablet will have about 50-70% of amoxicillin and 25-40% of clavulanic acid excreted unchanged in urine within 6 hours. This medication is used to treat various bacterial infections, including respiratory and urinary tract infections, and can be administered orally, with a typical dosage for adults being 250mg amoxicillin every 8 hours or 500mg every 12 hours, though doses can vary depending on the severity of infection. For more information about this product, you can visit the Denk Pharma website.

Clavam XR

Clavam XR, manufactured by Alkem Laboratories, is a brand known for producing an extended-release tablet combining amoxicillin (1000mg) and clavulanic acid (62.5mg), typically used to treat bacterial infections such as sinusitis and pneumonia, with a recommended dosage of two tablets every 12 hours for 7-10 days, but is not recommended for S. pneumoniae infections with penicillin MICs ≥ 4 mcg/mL. The Clavam XR formulation is designed to enhance amoxicillin absorption and minimize gastrointestinal issues when taken at the start of a meal and is not interchangeable with other Clavam formulations. This medication is available in a strip of 10 tablets. You can find more information about the product on the Alkem Laboratories website.

Megamox

Megamox is a well-regarded brand known for producing amoxicillin and clavulanic acid combination medications, which are used to treat a wide range of bacterial infections, including respiratory, urinary, and skin infections; these medications combine amoxicillin, typically at doses like 500mg or 875mg, with clavulanic acid at 125mg, which helps to overcome bacterial resistance; Megamox products, available in tablet form and sometimes as injections, are often prescribed for infections like otitis media and sinusitis and are effective due to clavulanic acid inactivating bacterial enzymes that would otherwise break down the amoxicillin, ensuring its optimal function; The brand offers various dosages, such as 625mg tablets (with 500mg amoxicillin and 125mg clavulanic acid) and 1gm tablets (with 875mg amoxicillin and 125mg clavulanic acid) to cater to different treatment needs and patient populations; Megamox formulations aim to deliver a reliable and effective antibiotic solution for a broad spectrum of bacterial infections by combining amoxicillin and clavulanic acid.