Top Whey Isolate Brands for Premium Protein Boost

Whey isolate, a popular protein supplement known for its high protein content and low levels of fats and carbohydrates, has garnered attention among fitness enthusiasts and health-conscious individuals alike. With so many brands in the market, choosing the right one can be overwhelming, as factors such as taste, mixability, and quality can significantly impact consumer preferences. Renowned brands have set themselves apart by not only ensuring top-notch quality but also offering a variety of flavors and formulations to cater to diverse needs. Below, you'll find a carefully curated list of some of the best whey isolate brands available today.

Illustration of whey isolate

Best brands of whey isolate in 2025

Optimum Nutrition

Optimum Nutrition, established in 1986, is a leading sports nutrition brand known for its Gold Standard 100% Whey Isolate, a product that uses a high-quality whey protein isolate as its primary ingredient, providing 24-25 grams of protein and 5.5 grams of naturally occurring BCAAs per serving, and is considered the world's best-selling whey protein powder. This isolate undergoes sophisticated filtration to remove excess fat and sugar, resulting in a product with at least 80% protein, less than 1 gram of sugar and 1 gram of carbs, and is designed for fast absorption.

Dymatize Nutrition

Dymatize Nutrition, established in 1994, is a leading global brand, providing high-quality supplements, including their popular ISO100 whey protein isolate, which boasts 25 grams of protein per serving with a high protein percentage, is fast-absorbing, and is often hydrolyzed for quick digestion; this product is known for its low carb and sugar content with only 1g of sugar per serving, and it is available in various flavors. You can find their products on their official website: Dymatize Nutrition official website.

Myprotein

Myprotein, established in 2004, is a leading European brand that produces high-quality whey isolate, known for its impressive 90% protein content per serving with minimal fat and carbs, offering 20-23g of protein per 25g scoop, and it has been recognized by Labdoor as a top-rated protein supplement for quality and value; this isolate is also rich in essential amino acids, including BCAAs, which help in muscle growth and recovery and is available in various flavors.

BSN

BSN (Bio-Engineered Supplements and Nutrition), established in 2001, is a global leader in sports nutrition, renowned for producing high-quality whey isolate, like their Syntha-6 Isolate which offers a blend of fast and slow digesting proteins with 25 grams of protein per serving, while minimizing fat and carbs. Although not a pure 100% isolate, the product is a 50/50 blend of whey protein isolate and milk protein isolate and is praised for its great taste and mixability, making it a top choice for post-workout recovery. You can find more information about BSN products at their official website.

MuscleTech

MuscleTech, established in 1995, is a leading brand known for its high-quality whey isolate, particularly the Nitro-Tech series, which is formulated to build 70% more lean muscle compared to regular whey protein. Each serving typically provides 30g of protein, 3g of creatine, and 6.8g of BCAAs, while their IsoWhey product offers 25g of protein with 0g of added sugar and 110 calories per serving. The brand's commitment to research and development is evident in their scientifically engineered formulas.

Isopure

Isopure, established in 1984, is a well-regarded brand under Glanbia Performance Nutrition, known for producing high-quality whey protein isolate, often containing 25 grams of protein per serving. Their products are made with 100% whey protein isolate, with many options being low carb, and they are popular among those seeking gluten and lactose-free options. Isopure's protein powders are known for their purity, with some options containing zero carbs, sugar, and fat, and they are designed for easy mixing into various foods and beverages.

Ascent Protein

Ascent Protein, established in 2016, has quickly become a leading brand in the sports nutrition industry, renowned for its high-quality whey protein isolate. Their products boast an impressive 25 grams of protein per serving with zero artificial ingredients, making it a favorite among athletes and fitness enthusiasts. Ascent's commitment to purity and performance is evident in their rigorous testing and sourcing of raw materials. The brand's dedication ensures that consumers receive a product with a high protein content, typically around 90% pure protein. You can explore their range of products at Ascent Protein's official website.

Jay Robb

Jay Robb, established in 1988, is a leading producer of premium whey protein isolate, utilizing cold-processed cross-flow microfiltration from grass-fed cows not treated with rBGH, delivering 25 grams of protein per 30 gram serving with less than 1 gram of sugar, and no fat. This brand is known for its clean ingredients, avoiding artificial sweeteners, and providing a high-quality protein option for health-conscious individuals, and is considered the number 1 premium brand of protein in America. Jay Robb whey isolate comes in different flavors such as vanilla and chocolate, and is available in various sizes, including 24 oz and 80 oz containers.

Pro JYM

Pro JYM, established in 2013, is a leading producer of whey isolate, utilizing a blend of 40% fast-digesting whey protein isolate, 50% slow-digesting casein, and 10% medium-digesting egg protein in each serving to provide a sustained release of amino acids. Each scoop delivers 24 grams of whole proteins, supporting lean muscle growth and recovery. This protein powder avoids the use of cheap amino acids, ensuring a high-quality blend for optimal muscle protein synthesis, and is available in various flavors with minimal carbs and fat.

Transparent Labs

Transparent Labs has established itself as a premier producer of whey isolate, boasting a protein content of 90% or more in their products, with the company being founded in 2017. Their commitment to clean ingredients and rigorous third-party testing ensures a high-quality protein option for athletes and fitness enthusiasts. Additionally, they offer various flavors and sizes, catering to different preferences and needs; therefore, Transparent Labs is recognized as a leader in the supplement industry.