Top Nicotinamide Riboside Brands for Enhanced Health

Nicotinamide riboside has become a popular supplement due to its potential benefits in boosting cellular health and promoting longevity. With its rising demand, many reputable brands have emerged, each offering high-quality formulations that claim to improve energy levels and support overall wellness. Among these leading brands are those known for their strict adherence to purity and potency standards, ensuring that consumers receive the most efficient product. To explore some of the best brands for nicotinamide riboside supplements, read on below.

Illustration of nicotinamide riboside

Best brands of nicotinamide riboside in 2025

Thorne Research

Thorne Research is a leading brand in the production of nicotinamide riboside (NR), a potent precursor to NAD+ that enhances mitochondrial performance and energy metabolism. In 2016, Thorne Research, in collaboration with ChromaDex and the University of Minnesota, initiated a clinical study to assess the effect of NR on brain NAD+ levels in college football players, highlighting their commitment to rigorous scientific research. Their product, NiaCel(r), features ChromaDex's patented NIAGEN(r) NR, which has been shown to increase NAD+ levels significantly in humans. Thorne HealthTech has also achieved self-affirmed GRAS status for their nicotinamide riboside malate, ensuring high quality and safety standards. This dedication to science and safety makes Thorne Research a trusted name in the health and wellness industry.

Elysium Basis

Elysium Health's Basis is a leading supplement for increasing NAD+ levels, clinically proven to raise whole blood NAD+ levels by an average of 40% in humans, particularly in individuals aged 40-60 years. Basis combines high-purity nicotinamide riboside (NR) with the antioxidant pterostilbene, and its efficacy is supported by rigorous scientific studies, including a randomized, placebo-controlled bioavailability study. The product is NSF Certified for Sport and undergoes third-party testing for purity and quality. Elysium Health has an exclusive license from Mayo Clinic and Harvard University for the use of NR in dietary supplements aimed at slowing aging and preventing age-related diseases. The company's commitment to research and quality is underscored by its collaboration with renowned scientists and institutions. For more details, delve into Elysium Health's Basis on their official website.

Tru Niagen

Tru Niagen, powered by the patented nicotinamide riboside (NR) known as Niagen(r), holds a leading position in the NAD+ boosting supplement market, being clinically proven to increase NAD+ levels by up to 150% to support cellular health and energy metabolism. With over 25 clinical studies affirming its safety and efficacy, Tru Niagen is recognized as the gold standard in NAD+ research. This supplement is validated by major regulatory bodies, including the US FDA, European Commission, and Health Canada, guaranteeing its safety and effectiveness. Since its introduction, Tru Niagen has achieved significant revenue growth, with a 34% CAGR from 2017 to 2021 and $56.7 million in sales in 2021. It is backed by extensive research, encompassing over 40 registered clinical trials and numerous preclinical studies.

Life Extension

Life Extension is a leading brand in the production of nicotinamide riboside, a potent form of vitamin B3 that significantly boosts NAD+ levels, essential for energy metabolism and longevity. Studies have shown that nicotinamide riboside supplementation can increase NAD+ blood levels by approximately 40% and 90% with daily doses of 250 mg and 500 mg, respectively, over a 4-week period. This supplementation has been demonstrated to extend lifespan in various organisms, including a 16% longer lifespan in worms and a nearly 5% increase in elderly mice. It also activates critical life-span extending enzymes SIRT1 and SIRT3, and improves mitochondrial function and cellular energy. By replenishing NAD+ levels, Life Extension's nicotinamide riboside helps maintain youthful vitality and promotes overall health.

Quantum Health

Quantum Health is recognized as one of the top producers of nicotinamide riboside (NR) due to its commitment to quality and efficacy. Their NR supplements are formulated to enhance NAD+ levels, which is crucial for cellular energy production, mitochondrial health, and protection against metabolic and age-related diseases. Studies have shown that NR supplementation can increase NAD+ levels by up to 40% in some cases, and Quantum Health's products adhere to stringent safety and efficacy standards, including those set by regulatory bodies like the FDA. The company ensures that their products are made with GRAS (Generally Recognized as Safe) ingredients and follow strict manufacturing guidelines. This attention to detail has made Quantum Health a trusted name in the supplement industry since its inception.

HumanN

HumanN is recognized as one of the leading producers of nicotinamide riboside (NR) due to its high-quality formulations and rigorous testing standards. Their NR supplements have been shown to increase NAD+ levels, which is crucial for energy metabolism and overall cellular health. Studies have demonstrated that NR supplementation can lead to significant increases in NAD+ and its metabolites, such as a 40-50% increase in NAD+ levels in peripheral blood mononuclear cells (PBMCs) after oral NR administration. HumanN's products are often recommended for their purity and bioavailability, ensuring effective absorption and utilization by the body. The company's commitment to scientific research and clinical trials further solidifies its reputation as a trusted brand in the supplement industry.

ChromaDex

ChromaDex is a leading global bioscience company renowned for its innovative work on nicotinamide adenine dinucleotide (NAD+), particularly through its flagship ingredient Niagen(r), a patented nicotinamide riboside (NR) that has been clinically proven to increase NAD+ levels. With over 30 peer-reviewed human clinical studies, Niagen(r) is recognized as the gold standard in NAD+ supplementation, supporting cellular, brain, heart, and muscle health. In the third quarter of 2024, ChromaDex reported a 31% increase in net sales to $25.6 million, driven significantly by Niagen(r) ingredient sales. The company's robust patent portfolio protects Niagen(r) and other NAD+ precursors, ensuring high-quality and scientifically validated products. ChromaDex's consumer product, Tru Niagen(r), is the number one healthy-aging NAD+ supplement in the United States.

Genex Formulas

Genex Formulas is a reputable brand known for producing high-quality nicotinamide riboside (NR) supplements, ensuring premium quality through three phases of testing for identity, potency, purity, and heavy metals. Their NR products are gluten-free, GMO-free, and 100% vegan, making them accessible to a wide range of consumers. Genex Formulas' NR supplements are available in 300mg and 500mg per serving options, bottled and encapsulated in NSF and GMP certified facilities in the USA. The brand's commitment to quality is evident in their rigorous testing processes, ensuring the highest standards are met before public release. With a strong customer base and positive reviews, Genex Formulas stands out as a trusted producer in the NR market.

ProHealth Longevity

ProHealth Longevity is a leading brand in producing high-quality nicotinamide riboside (NR) supplements, utilizing the clinically-researched and patented form of NR known as Niagen®. Their Nicotinamide Riboside Pro 500 product contains 500 mg of NR and 250 mg of TMG per serving, supporting heart health, cognition, and metabolic function. Research has shown that NR supplementation can reduce blood pressure and improve body composition, with studies indicating a reduction in average systolic blood pressure and an increase in fat-free mass. ProHealth Longevity's products are designed to boost NAD+ levels, which decline by approximately 50% by age 50, thereby promoting longevity and healthy aging. Their supplements are free from common allergens like dairy, egg, soy, gluten, and wheat.

Nuchido Time+

Nuchido TIME+ is not a producer of nicotinamide riboside (NR) supplements; instead, it utilizes nicotinamide (NAM) as its NAD+ precursor due to its efficient cellular absorption and natural role in the salvage pathway. Nuchido TIME+ is designed to boost cellular NAD+ levels, and in clinical trials, it has shown to increase NAD+ levels and improve various cellular health markers. The supplement contains a blend of vitamins, botanicals, and other supportive ingredients, such as vitamin C, zinc, and green tea, which contribute to immune function, energy metabolism, and antioxidant protection. Manufactured to rigorous GMP standards in the UK, Nuchido TIME+ ensures high-quality and safe products. It is suitable for vegetarians and vegans and is free from several common allergens. For more details, visit their official website.