Top N-Acetylcysteine Brands for Optimal Wellness

N-acetylcysteine (NAC) is a popular supplement renowned for its antioxidant properties and benefits in supporting liver health and respiratory function. As interest in this supplement grows, choosing a high-quality brand becomes essential for ensuring efficacy and safety. Several brands stand out in the market for their commitment to purity, science-backed formulations, and consumer trust. To help you make an informed decision, we've compiled a list of the best NAC brands available today. Read on to discover which companies offer the most reliable and effective N-acetylcysteine supplements.

Illustration of n acetylcysteine

Best brands of n acetylcysteine in 2025

Jarrow Formulas

Jarrow Formulas is a well-regarded producer of N-Acetyl Cysteine (NAC), with many customers praising its effectiveness and quality, often citing noticeable health benefits such as improved lung function and detoxification. It offers both 500mg and 600mg dosages in vegetarian capsules, with the 600mg version utilizing a sustained-release formula for prolonged effects. A 2022 report highlighted Jarrow's NAC as a potent antioxidant and glutathione precursor, supporting liver health and immune function.

NOW Foods

NOW Foods, established in 1968, is a reputable brand providing high-quality N-Acetyl Cysteine (NAC) supplements, typically at a dosage of 600mg per capsule, that act as a stabilizer for protein structures and are necessary for glutathione production; their NAC products often include 25mcg of Selenium for enhanced enzyme production, and are produced in GMP facilities, ensuring that they are non-GMO, and free from common allergens such as gluten, soy, and nuts, with both 100 and 250 capsule options available.

Thorne Research

Thorne Research is a well-regarded brand, established in 1984, that produces high-quality N-acetylcysteine (NAC) supplements, with each capsule containing 500mg of NAC, a potent antioxidant that supports liver and kidney detoxification, promotes respiratory health by helping to clear mucus, and enhances immune function by boosting glutathione production; Thorne's NAC product is trusted by over 100 professional sports teams and is known for its rigorous testing and high-quality ingredients, with many customers reporting improved overall health.

Life Extension

Life Extension is recognized as a high-quality producer of N-Acetyl Cysteine (NAC), with each capsule containing 600mg of this potent nutrient, supporting immune health, liver function, and acting as a strong antioxidant. Multiple studies suggest NAC positively affects energy production and overall well-being; though some users have reported an unpleasant smell, Life Extension's NAC is laboratory tested for purity and is available in easy-to-swallow capsules, often praised for its quality and effectiveness.

Pure Encapsulations

Pure Encapsulations is a reputable brand known for producing high-quality N-acetylcysteine (NAC) supplements, offering both 600mg and 900mg capsules with free-form NAC, derived from a dietary amino acid, that acts as a powerful antioxidant supporting lung health, increasing glutathione levels, and aiding in detoxification, with some studies suggesting that NAC supplementation for six months supported upper respiratory tract and immune system health. Their NAC is also considered a safe supplement, with a low risk of side effects, and is often recommended in dosages between 600-1800mg daily.

Solgar

Solgar, a brand recognized for its commitment to quality, has been producing N-Acetyl Cysteine (NAC) supplements, typically at a dosage of 600mg per capsule, with their product being a popular choice for those seeking antioxidant and liver detoxification support; Solgar's NAC is a free-form amino acid, promoting optimal absorption, and is offered in vegan, kosher, and gluten-free formulations, and is known for excluding artificial flavors, sweeteners, and preservatives; the brand has been committed to health and well-being for 75 years and their NAC product has been sold for more than 30 years in the United States with no safety concerns, further cementing its reputation. Solgar's NAC supplements are widely available through various retailers, with the brand having released a product that contains NAC and Glycine, with research in 2023 showing its ability to reduce oxidative stress.

Doctor's Best

Doctor's Best is a well-regarded brand for N-Acetyl Cysteine (NAC), with their NAC Detox Regulators product, which often includes selenium and molybdenum, to support glutathione production, a key antioxidant in the body. This product has been used by customers for up to 7 years, with many reporting improved detoxification and energy levels. Doctor's Best NAC is known to help boost glutathione production in the brain, liver, and other organs, aiding in the neutralization of toxins and promoting healthy protein function. The combination of NAC with selenium and molybdenum enhances the body's natural detoxification processes and helps maintain healthy glutathione levels.

Swanson

Swanson brand is a well-regarded producer of N-acetylcysteine (NAC) supplements, offering products like their 600mg capsules, which are frequently praised for their antioxidant properties and ability to support liver health by boosting glutathione levels, with many users reporting positive experiences regarding mood and ease of use, although some have mentioned mild side effects. Swanson has been delivering science-backed health products for nearly 50 years, and their NAC supplements are made in GMP-certified facilities, ensuring quality. The company offers a 30-day money-back guarantee if not satisfied. NAC, a precursor to L-cysteine, supports the body in neutralizing free radicals, thus helping with immune, neuronal, and cardiovascular health. Additionally, Swanson's NAC supplements, including 1000mg options, are known for promoting healthy respiratory function and overall detoxification pathways. Their NAC product also provides the building blocks for glutathione production, the body's master antioxidant, which is important for fighting oxidative stress and promoting healthy aging.

Designs for Health

Designs for Health is a reputable brand offering high-quality N-Acetyl Cysteine (NAC) supplements, with their products often providing 900mg of NAC per capsule, designed to support glutathione production, a powerful antioxidant in the body. Available in both capsule and powder form, the pure NAC powder is easy to dissolve. This brand's NAC is known to support liver function, detoxification, lung health, and muscle recovery; their products are typically non-GMO, gluten-free, and vegetarian-friendly.

Klaire Labs

Klaire Labs, a brand trusted by healthcare practitioners since 1969, offers a high-quality N-Acetyl-L-Cysteine (NAC) supplement, with each vegetarian capsule containing 500mg of this amino acid precursor to glutathione, which supports cellular antioxidant protection and detoxification, and is also free of common allergens like soy and corn. This product, often used as a preferred substrate for intracellular glutathione synthesis, can be taken 1-2 capsules daily, and while Klaire Labs has been part of the SFI Health family since 2013, their commitment to quality remains consistent as they transition their brand to SFI Health.