Top Citrulline Powerhouses: Leading Brands You Need to Know

Citrulline, often praised for its potential benefits in enhancing athletic performance and boosting nitric oxide production, has captured the attention of fitness enthusiasts and health-conscious individuals alike. With a plethora of brands flooding the market, finding a reliable product that meets your needs can be overwhelming. To help streamline your decision-making process, we have compiled a list of the top-rated citrulline brands known for their quality, purity, and efficacy. Discover which brands made the cut and why they've become favorites among consumers and fitness professionals below.

Illustration of citrulline

Best brands of citrulline in 2025

Bulk Powders

Bulk Powders, such as those from Bulk Supplements and LifeLab, are highly regarded for their high-quality L-Citrulline products, often boasting purity levels of up to 99.87%. These powders are frequently used by athletes and bodybuilders to enhance physical performance, improve blood flow, and support overall health. L-Citrulline from these brands is gluten-free, allergen-free, and has no added sugar, making it a preferred choice for those with dietary restrictions. The recommended dosage is typically 2-3 grams per serving, taken up to three times daily, and it is best consumed in the morning before training. These products are also certified suitable for vegetarians and vegans.

Optimum Nutrition

Optimum Nutrition is renowned as one of the best producers of citrulline supplements, particularly through their Platinum Pre-Workout(tm) and Platinum Pump Pre-workout formulas. These products feature high doses of L-citrulline, with the Platinum Pre-Workout(tm) containing 6g of L-citrulline, an amount supported by studies to enhance performance. The Platinum Pump Pre-workout offers 8g of L-citrulline, making it a caffeine-free alternative that still supports intense workouts. Optimum Nutrition's formulations are scientifically backed and designed to optimize athletic performance, energy production, and muscle endurance. Their products are tailored for various fitness needs, whether for competitive athletes or casual gym-goers.

NOW Foods

NOW Foods is a prominent player in the global L-citrulline market, known for its high-quality citrulline supplements that cater to the growing demand in sports nutrition and health supplements. The company's products, such as citrulline supplements, are popular among fitness enthusiasts and athletes due to their purity and effectiveness in enhancing athletic performance and muscle recovery. In 2023, the global L-citrulline market, which includes NOW Foods, saw a significant surge, particularly in North America, with the U.S. consumption rate rising by approximately 8-10% compared to 2022. NOW Foods, along with other key players like Kyowa Hakko Bio Co. and NutraBio Labs, has contributed to the market's growth, expected to continue at a CAGR of 5.98% from 2024 to 2030. The company's strong brand reputation and extensive product portfolio have solidified its position in the market.

Cellucor

Cellucor is a prominent brand in the L-citrulline market, known for its high-quality formulations that cater to the growing demand for sports nutrition and health supplements. Their products, such as the C4 Ultimate Pre Workout Powder, feature a blend of L-Citrulline and L-Arginine to enhance muscle pumps and performance. The global L-citrulline market, driven in part by brands like Cellucor, is expected to grow at a CAGR of 5.98% from 2024 to 2030, reaching nearly USD 1.66 billion by 2030. In North America, where Cellucor has a strong presence, the market captured a revenue share of over 32.87% in 2023, driven by rising consumer awareness and preference for nutritional supplements. Cellucor's products are backed by 20 years of sports nutrition expertise, ensuring innovative and effective supplements.

Jarrow Formulas

Jarrow Formulas is renowned for its high-quality dietary supplements, particularly its Arginine-Citrulline Sustain™ product, which combines sustained-release arginine and citrulline in equal amounts to support vascular health and nitric oxide production. Founded on a commitment to scientific research and quality, Jarrow Formulas has maintained superior science as its guiding principle for over 50 years. The company ensures purity and potency by adhering to Current Good Manufacturing Practices (cGMP) and collaborating with global researchers. The L-Citrulline Crystals Market, in which Jarrow Formulas is a key player, is forecasted to grow at a CAGR of 6.8% from 2024 to 2030, reaching a market size of $1306.7 million by 2030. Jarrow Formulas' products are free from common allergens like wheat, gluten, soybeans, and dairy, making them a reliable choice for health-conscious consumers.

Kaged Muscle

Kaged Muscle is renowned for producing high-quality, plant-based L-citrulline supplements, leveraging a unique fermentation process to ensure purity and effectiveness. Their citrulline products are free from artificial colors and flavors, and are certified by Informed-Sport, making them safe for athletes. The brand's Pre-Kaged Elite pre-workout features an industry-leading 10 grams of L-citrulline, which has been shown to enhance athletic endurance by up to 50% and reduce soreness by 50% according to research. Kaged Muscle supplements are formulated with ultra-premium ingredients and are third-party tested, ensuring cleanliness and efficacy. This commitment to quality has established Kaged as a formidable player in the sports nutrition industry since its inception.

Nutricost

Nutricost is renowned as one of the top producers of L-Citrulline supplements, known for its high-quality and third-party lab-tested products. The brand offers a 60-day money-back guarantee, reflecting its confidence in the efficacy of its supplements. Nutricost's L-Citrulline products, such as the L-Citrulline Malate 2:1 flavored powder, are popular among fitness enthusiasts for their potential to enhance endurance and muscle recovery. With a strong focus on customer satisfaction and quality assurance, Nutricost has established a significant market presence, particularly in the sports nutrition and dietary supplement sectors. The growing demand for natural and performance-enhancing supplements has driven the market growth, with the global L-Citrulline market expected to grow at a CAGR of 5.2% from 2024 to 2032.

Transparent Labs

Transparent Labs stands out as a premier producer of citrulline supplements, particularly with their PreSeries PUMP product, which features a clinically effective dose of 8,000 mg of L-citrulline per serving. This formulation is designed to enhance nitric oxide production, improve vascular function, and promote muscle fullness and recovery. The brand is committed to using 100% authentic ingredients and full-disclosure product labels, ensuring transparency and trust with their customers. With a focus on science-backed ingredients and no artificial sweeteners, colors, or fillers, Transparent Labs aligns with the growing demand for natural and vegan product offerings. The global L-citrulline market, which is expected to grow at a CAGR of 5.98% from 2024 to 2030, reflects the increasing consumer preference for such high-quality supplements.

Primeval Labs

Primeval Labs is renowned as one of the best producers of citrulline supplements, particularly through their pre-workout products like Ape Sh*t Untamed and Ape Sh*t Pumps. These supplements contain a significant dose of 4.5g to 6g of L-Citrulline per serving, which has been shown to increase ATP production by up to 34% and enhance exercise performance in various studies. The brand's formulations are designed to boost nitric oxide production, improve blood flow, and enhance muscle pumps, making them a favorite among athletes. With a focus on high-quality ingredients and effective dosing, Primeval Labs has established itself as a trusted name in the supplement industry since its inception. Their products are also known for their delicious flavors and minimal side effects, such as minor GI upset.

Doctor's Best

Doctor's Best is a renowned brand for producing high-quality L-Citrulline powder, known for its purity and effectiveness. Their L-Citrulline powder, made from Kyowa Quality ingredients, supports nitric oxide metabolism, enhances vascular health, and alleviates muscle soreness. Each serving of 3 grams contains 100% L-Citrulline, with no added or artificial flavors, colors, or preservatives, making it suitable for vegan, vegetarian, and those with dietary restrictions. The product is non-GMO, gluten-free, and soy-free, ensuring it meets stringent quality standards. With approximately 66 servings per 7 oz (200g) container, it is a reliable choice for those seeking to improve circulation and muscle health.