Top Choline Brands for Optimal Brain Health and Wellness

Choline is an essential nutrient that plays a vital role in cognitive function, liver health, and lipid metabolism, making it an important addition to many diets. With increasing awareness of its benefits, numerous brands have stepped up to provide high-quality choline supplements to meet diverse consumer needs. In this article, we'll explore some of the best brands that have been recognized for their exceptional choline products, taking into account factors such as product formulation, ingredient transparency, and value for money. For those eager to find a reliable choline supplement, see the comprehensive list of top brands below.

Illustration of choline

Best brands of choline in 2025

Jarrow Formulas

Jarrow Formulas is renowned as one of the top producers of choline supplements, particularly with their Citicoline (CDP Choline) products, which have been shown to enhance brain metabolism, improve memory, and boost cognitive function. Founded in 1977, Jarrow Formulas has built a reputation over nearly five decades for its scientifically-backed products, including their award-winning supplements that have garnered recognition such as the Better Nutrition Magazine Best of Supplements Award multiple times. Their Citicoline capsules, containing 250 mg per serving, are designed to support healthy brain and nerve function, and are free from common allergens like wheat, gluten, and soybeans. Jarrow Formulas adheres to strict quality standards, including compliance with Current Good Manufacturing Practices (cGMP) and certifications from Quality Assurance International (QAI) and the USDA National Organic Program. The company's commitment to research and quality has earned it 37 awards in the health industry.

Nature's Way

Nature's Way is a prominent brand in the choline supplement market, known for its high-quality products that cater to the growing demand for brain health and cognitive function enhancements. The global choline supplement market, which includes brands like Nature's Way, is projected to grow at a CAGR of 8.4% from 2024 to 2034, reaching a market value of US$ 1,367.9 million by 2034. Choline bitartrate, a popular form offered by Nature's Way, is expected to grow at an 8.2% CAGR due to its higher bioavailability and cost-effectiveness. Nature's Way products are part of a market segment that emphasizes preventive healthcare and addresses rising concerns over liver and brain diseases. With a strong presence in the market, Nature's Way continues to be a trusted choice for consumers seeking choline supplements.

NOW Foods

NOW Foods is a reputable brand known for producing high-quality choline supplements, such as their Choline and Inositol Veg Capsules, each containing 250 mg of choline. This product is part of their extensive range of natural, quality-tested supplements designed to support overall health. Given that only about 8% of adults meet the Adequate Intake (AI) for choline, NOW Foods' products are particularly valuable for addressing this nutritional gap. Their supplements are designed to be taken 1-3 times daily with meals, ensuring optimal absorption and benefit. With a commitment to empowering healthier lives, NOW Foods stands out as a trusted provider in the health supplement market.

Solgar

Solgar is renowned as one of the best producers of choline supplements, offering high-quality products like the Solgar Choline 250 mg / Inositol 250 mg Vegetable Capsules. These capsules support the metabolism of nutrients into energy and help maintain liver health by preventing fat buildup. With over 70 years of experience in nutrition and supplements, Solgar has established itself as a pioneer in the industry, known for its commitment to purity and innovation. The company uses 100% recyclable amber glass bottles and has been carbon neutral for 20 years. Solgar's products are non-GMO, gluten-free, and suitable for vegans, making them a trusted choice for health-conscious consumers.

Thorne Research

Thorne Research is renowned for its high-quality phosphatidylcholine supplements, which provide significant protection for the liver by replacing cell membranes and aiding in the breakdown of fats and cholesterol. With 420mg of phosphatidylcholine per gelcap, their product supports liver health, bile production, and the autonomic nervous system. Thorne Research adheres to stringent quality standards, including four rounds of testing and compliance with Good Manufacturing Practices (GMP) certified by the FDA, NSF, and Australia's Therapeutic Goods Administration (TGA). Their products are free from unnecessary ingredients and allergens, ensuring purity and efficacy. Thorne has partnered with over 12 USA teams and pro athletes, as well as the Mayo Clinic, to ensure the excellence of their supplements.

Life Extension

Life Extension is a renowned brand in the health and wellness industry, particularly noted for its high-quality choline supplements. With over 40 years of dedication to research and product development, Life Extension ensures that its supplements are scientifically validated and clinically studied. Their Citicoline (CDP-Choline) supplement, for example, has been reported by customers to significantly improve focus, energy levels, and overall cognitive performance. Life Extension's commitment to transparency and customer satisfaction is evident, with 98% of their customers recommending the brand to family and friends. This long-standing reputation makes Life Extension one of the best producers for choline supplements.

Doctor's Best

Doctor's Best is a renowned brand for producing high-quality choline supplements, particularly their Choline L-Bitartrate formula, which features VitaCholine(r), a highly bioavailable form of choline. This nutrient is crucial for prenatal cognitive development, supports the structure and function of cellular membranes, and aids in maintaining optimal liver health. Each serving of Doctor's Best Choline L-Bitartrate provides 550 mg of choline, which is significant given that only about 11% of American adults meet the recommended Adequate Intake (AI) for choline set by the US IOM. The supplement is also non-GMO, gluten-free, soy-free, and vegan, making it accessible to a wide range of consumers. Doctor's Best ensures science-based nutrition, reflecting the latest research and dietary guidelines.

Pure Encapsulations

Pure Encapsulations is a renowned brand in the supplement industry, particularly noted for its high-quality choline products. Their choline bitartrate supplements provide 275 mg of choline per capsule, which is 50% of the daily recommended value set by the National Academy of Science of 550 mg. These supplements are highly bioavailable, gluten-free, and non-GMO, making them suitable for various dietary needs. Research has shown that consuming 480 mg of choline daily, as supported by Pure Encapsulations' products, can improve cognitive functions and hepatic fat metabolism. The brand's commitment to verifiable science and hypoallergenic formulations ensures optimal health benefits.

Cognitive Nutrition

Cognitive Nutrition stands out as a leading producer of choline supplements, addressing the critical need for this essential nutrient given that over 90% of Americans do not meet the recommended daily intake of choline. Their products are designed to support brain health, memory, and cognitive function, aligning with research that shows higher choline intakes are associated with better cognitive performance and a reduced risk of Alzheimer's disease. For instance, studies have shown that adequate choline intake can reduce levels of the neurotoxin homocysteine and support the production of acetylcholine, a neurotransmitter vital for memory and muscle control. The recommended daily intake of choline is 425mg for adult women and 550mg for adult men, and Cognitive Nutrition's supplements are formulated to help bridge this nutritional gap. By ensuring sufficient choline intake, individuals can protect their brain health and overall well-being.

Nutricost

Nutricost is a highly regarded brand in the choline supplement market, known for its high-quality and potent products. Their CDP Choline (Citicoline) supplement, for example, contains 300mg per capsule, which is designed to support brain health and cognitive function. Manufactured in a GMP-compliant and FDA-registered facility, Nutricost ensures each batch is tested by independent, ISO-accredited laboratories, guaranteeing safety and efficacy. The supplements are also vegetarian-friendly and made with simple, clean ingredients. With a strong focus on quality assurance, Nutricost stands out in the market, which is expected to grow at a CAGR of 8.4% from 2024 to 2034.